SNF12_YEAST - dbPTM
SNF12_YEAST - PTM Information in dbPTM
Basic Information of Protein
UniProt ID SNF12_YEAST
UniProt AC P53628
Protein Name Transcription regulatory protein SNF12
Gene Name SNF12
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length 566
Subcellular Localization Nucleus.
Protein Description Involved in transcriptional activation. Component of the SWI/SNF complex, an ATP-dependent chromatin remodeling complex, which is required for the positive and negative regulation of gene expression of a large number of genes. It changes chromatin structure by altering DNA-histone contacts within a nucleosome, leading eventually to a change in nucleosome position, thus facilitating or repressing binding of gene-specific transcription factors..
Protein Sequence MSKVMKPSNGKGSRKSSKAATPDTKNFFHAKKKDPVNQDKANNASQITPTVPHSHPSDMVIPDHLAELIPELYSFQQLVDSEKRLDHFIHLRNLHMKRMVAQWERSKLSQEFLYPHLNFPNVKFLRIFISNVSENQPWQMDTNNEADLMALENATWTMRIEGRLLDNVQANDPAREKFSSFIESIVVDFKNKENDNVPSTKFNAAPEENATEGPSDKKLNLNLPLQFSLPNGDNSTTTNTDQNNATMGEETAKKDMSSTTPKLESVKWQYDPNNPVDFDGLDIKRVGSENVECTISILRKSSPEEPFMSYSPQLTAIIGLKSGTSHDAIFSIYKYIHLNELLTNDESAFENLMGNRNNHNSNTSTSKMLDAASSQVSIVKLDTQLITLLPSSLKESSPDTMKLTDLLSLINSTHLLPLQPIEIDYTVRVDKASTYGELVLDIEVPDVNALKFNNTQRESQIGAAELNENARELEQIKPKIALQDKEITSVLSNLHESNKRYRFFKKISEDPVKALNECIASTSNALKVLSGDEGYNEDMVRRANFYKENEAMLRENIEVILSNGRM
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
8PhosphorylationMSKVMKPSNGKGSRK
CCCCCCCCCCCCCCC		53.3430377154
13PhosphorylationKPSNGKGSRKSSKAA
CCCCCCCCCCCCCCC		39.7730377154
21PhosphorylationRKSSKAATPDTKNFF
CCCCCCCCCCCCCCC		26.9327214570
142PhosphorylationNQPWQMDTNNEADLM
CCCCCCCCCCHHHHH		34.3027017623
155PhosphorylationLMALENATWTMRIEG
HHHHHCCEEEEEEEC		32.8127017623
157PhosphorylationALENATWTMRIEGRL
HHHCCEEEEEEECEE		7.6927017623
201AcetylationNDNVPSTKFNAAPEE
CCCCCCCCCCCCCCC		40.7422865919
217AcetylationATEGPSDKKLNLNLP
CCCCCCCCCCCCCCC		64.5924489116
257PhosphorylationETAKKDMSSTTPKLE
HHHHHHHCCCCCCHH		34.3722369663
258PhosphorylationTAKKDMSSTTPKLES
HHHHHHCCCCCCHHH		29.6622369663
259PhosphorylationAKKDMSSTTPKLESV
HHHHHCCCCCCHHHC		39.5522369663
260PhosphorylationKKDMSSTTPKLESVK
HHHHCCCCCCHHHCC		22.0020377248
288PhosphorylationLDIKRVGSENVECTI
CEEEEECCCCEEEEE		24.1228889911
296PhosphorylationENVECTISILRKSSP
CCEEEEEEEEECCCC		9.4528889911
331PhosphorylationTSHDAIFSIYKYIHL
CCHHHHHHHHHHHHH		20.9230377154
373PhosphorylationSKMLDAASSQVSIVK
HHHHHHHHCCEEEEE		24.0325882841
459PhosphorylationFNNTQRESQIGAAEL
CCCCHHHHHHCHHHH		29.3227017623
485AcetylationPKIALQDKEITSVLS
CCHHHCCHHHHHHHH		37.7524489116
497PhosphorylationVLSNLHESNKRYRFF
HHHHHHHHCHHHHHH		36.5823749301
499UbiquitinationSNLHESNKRYRFFKK
HHHHHHCHHHHHHHH		61.1523749301
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of SNF12_YEAST !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of SNF12_YEAST !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of SNF12_YEAST !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
MIG1_YEASTMIG1genetic
11281938
NRG1_YEASTNRG1genetic
11281938
SRS2_YEASTSRS2genetic
21459050
ATC3_YEASTDRS2genetic
27708008
ICE2_YEASTICE2genetic
27708008
RPN6_YEASTRPN6genetic
27708008
SNU23_YEASTSNU23genetic
27708008
RPN5_YEASTRPN5genetic
27708008
TAF12_YEASTTAF12genetic
27708008
TRS23_YEASTTRS23genetic
27708008
PRP3_YEASTPRP3genetic
27708008
ACT_YEASTACT1genetic
27708008
RPN12_YEASTRPN12genetic
27708008
CDC20_YEASTCDC20genetic
27708008
COPB2_YEASTSEC27genetic
27708008
SWC4_YEASTSWC4genetic
27708008
CDC23_YEASTCDC23genetic
27708008
UTP9_YEASTUTP9genetic
27708008
SMC3_YEASTSMC3genetic
27708008
YJ9I_YEASTYJR141Wgenetic
27708008
PRS7_YEASTRPT1genetic
27708008
NSE1_YEASTNSE1genetic
27708008
BOS1_YEASTBOS1genetic
27708008
CDC45_YEASTCDC45genetic
27708008
NEP1_YEASTEMG1genetic
27708008
UTP13_YEASTUTP13genetic
27708008
SEN1_YEASTSEN1genetic
27708008
UTP15_YEASTUTP15genetic
27708008
VTI1_YEASTVTI1genetic
27708008
PRS10_YEASTRPT4genetic
27708008
EI2BG_YEASTGCD1genetic
27708008
GPN2_YEASTGPN2genetic
27708008
RRS1_YEASTRRS1genetic
27708008
TBF1_YEASTTBF1genetic
27708008
SWC3_YEASTSWC3genetic
27708008
SLA1_YEASTSLA1genetic
27708008
HIR1_YEASTHIR1genetic
27708008
YBI1_YEASTYBL081Wgenetic
27708008
SEC66_YEASTSEC66genetic
27708008
AIM4_YEASTAIM4genetic
27708008
SWC5_YEASTSWC5genetic
27708008
MRC1_YEASTMRC1genetic
27708008
SNT1_YEASTSNT1genetic
27708008
THRC_YEASTTHR4genetic
27708008
RLA1_YEASTRPP1Agenetic
27708008
CYK3_YEASTCYK3genetic
27708008
TGL2_YEASTTGL2genetic
27708008
MRX8_YEASTYDR336Wgenetic
27708008
VPS74_YEASTVPS74genetic
27708008
ERD1_YEASTERD1genetic
27708008
BUD27_YEASTBUD27genetic
27708008
FAB1_YEASTFAB1genetic
27708008
COG7_YEASTCOG7genetic
27708008
CWC26_YEASTBUD13genetic
27708008
HOS2_YEASTHOS2genetic
27708008
UPF3_YEASTUPF3genetic
27708008
PFD3_YEASTPAC10genetic
27708008
DBF2_YEASTDBF2genetic
27708008
TBP7_YEASTYTA7genetic
27708008
REXO1_YEASTRNH70genetic
27708008
GOSR1_YEASTGOS1genetic
27708008
PTPA1_YEASTRRD1genetic
27708008
IMPX_YEASTIMP2genetic
27708008
IST3_YEASTIST3genetic
27708008
SYS1_YEASTSYS1genetic
27708008
RPE_YEASTRPE1genetic
27708008
PBS2_YEASTPBS2genetic
27708008
DPOD3_YEASTPOL32genetic
27708008
CBF1_YEASTCBF1genetic
27708008
HOC1_YEASTHOC1genetic
27708008
EAF6_YEASTEAF6genetic
27708008
ELM1_YEASTELM1genetic
27708008
MDM35_YEASTMDM35genetic
27708008
MUD2_YEASTMUD2genetic
27708008
XPOT_YEASTLOS1genetic
27708008
ENT4_YEASTENT4genetic
27708008
SSK1_YEASTSSK1genetic
27708008
RIC1_YEASTRIC1genetic
27708008
ARP6_YEASTARP6genetic
27708008
YPT6_YEASTYPT6genetic
27708008
VID22_YEASTVID22genetic
27708008
VIP1_YEASTVIP1genetic
27708008
SCS7_YEASTSCS7genetic
27708008
ADH6_YEASTADH6genetic
27708008
2A5D_YEASTRTS1genetic
27708008
PMA2_YEASTPMA2genetic
27708008
ARL3_YEASTARL3genetic
27708008
LGE1_YEASTLGE1genetic
27708008
MCFS1_YEASTEEB1genetic
27708008
YP109_YEASTYPL109Cgenetic
27708008
BRR1_YEASTBRR1genetic
27708008
CTF4_YEASTCTF4genetic
27708008
PDXH_YEASTYPR172Wgenetic
27708008
ATG13_YEASTATG13genetic
27708008
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of SNF12_YEAST

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Related Literatures of Post-Translational Modification

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