MCFS1_YEAST - dbPTM
MCFS1_YEAST - PTM Information in dbPTM
Basic Information of Protein
UniProt ID MCFS1_YEAST
UniProt AC Q02891
Protein Name Medium-chain fatty acid ethyl ester synthase/esterase 1
Gene Name EEB1
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length 456
Subcellular Localization
Protein Description Displays enzymatic activity both for medium-chain fatty acid (MCFA) ethyl ester synthesis and hydrolysis (esterase activity). MCFA are toxic for yeast and this enzyme could thus be involved in their detoxification by esterification..
Protein Sequence MFRSGYYPTVTPSHWGYNGTVKHVLGEKGTKSLAFRDSKRQIPLHEFVTKHVPTLKDGANFRLNSLLFTGYLQTLYLSAGDFSKKFQVFYGREIIKFSDGGVCTADWVMPEWEQTYSLNAEKASFNEKQFSNDEKATHPKGWPRLHPRTRYLSSEELEKCHSKGYSYPLVVVLHGLAGGSHEPLIRALSEDLSKVGDGKFQVVVLNARGCSRSKVTTRRIFTALHTGDVREFLNHQKALFPQRKIYAVGTSFGAAMLTNYLGEEGDNCPLNAAVALSNPWDFVHTWDKLAHDWWSNHIFSRTLTQFLTRTVKVNMNELQVPENFEVSHKPTVEKPVFYTYTRENLEKAEKFTDILEFDNLFTAPSMGLPDGLTYYRKASSINRLPNIKIPTLIINATDDPVTGENVIPYKQARENPCVLLCETDLGGHLAYLDNESNSWLTKQAAEFLGSFDELVL
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
22UbiquitinationWGYNGTVKHVLGEKG
CCCCCCEEECCCCCC		28.0317644757
28UbiquitinationVKHVLGEKGTKSLAF
EEECCCCCCCCEEEE		70.8123749301
31UbiquitinationVLGEKGTKSLAFRDS
CCCCCCCCEEEECCC		52.7417644757
39UbiquitinationSLAFRDSKRQIPLHE
EEEECCCCCCCCHHH		53.2417644757
50UbiquitinationPLHEFVTKHVPTLKD
CHHHHHHHCCCCCCC		36.9817644757
54PhosphorylationFVTKHVPTLKDGANF
HHHHCCCCCCCCCCE		45.4027017623
84UbiquitinationLSAGDFSKKFQVFYG
ECCCCHHHHEEEEEC		58.5617644757
85UbiquitinationSAGDFSKKFQVFYGR
CCCCHHHHEEEEECC		39.5717644757
128UbiquitinationEKASFNEKQFSNDEK
HHHCCCHHHCCCCCC		58.7223749301
159UbiquitinationLSSEELEKCHSKGYS
CCHHHHHHHHHCCCC		50.2817644757
163UbiquitinationELEKCHSKGYSYPLV
HHHHHHHCCCCCCEE		37.9017644757
194UbiquitinationALSEDLSKVGDGKFQ
HHHHHHHHHCCCCEE		58.4917644757
199UbiquitinationLSKVGDGKFQVVVLN
HHHHCCCCEEEEEEE		37.0523749301
237UbiquitinationREFLNHQKALFPQRK
HHHHHHCHHHCCCCC		39.2317644757
288UbiquitinationDFVHTWDKLAHDWWS
HHHHHHHHHHHHHHH		38.8517644757
312UbiquitinationQFLTRTVKVNMNELQ
HHHHCEEECCCCCCC		27.5517644757
329UbiquitinationENFEVSHKPTVEKPV
CCEECCCCCCCCCCE		34.5717644757
334UbiquitinationSHKPTVEKPVFYTYT
CCCCCCCCCEEEEEE		41.9917644757
350UbiquitinationENLEKAEKFTDILEF
HHHHHHHHHCHHHHC		59.4317644757
377UbiquitinationDGLTYYRKASSINRL
CCCEEEEECHHCCCC		36.1817644757
388UbiquitinationINRLPNIKIPTLIIN
CCCCCCCCCCEEEEE		49.6317644757
410UbiquitinationGENVIPYKQARENPC
CCCCCCHHHHCCCCE		31.9317644757
442UbiquitinationESNSWLTKQAAEFLG
CCCCHHHHHHHHHHC		35.4517644757
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of MCFS1_YEAST !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of MCFS1_YEAST !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of MCFS1_YEAST !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
YIP4_YEASTYIP4physical
11283351
YIP1_YEASTYIP1physical
11283351
TVP15_YEASTTVP15physical
18719252
RCY1_YEASTRCY1genetic
27708008
SEC17_YEASTSEC17genetic
27708008
RPAB1_YEASTRPB5genetic
27708008
MED8_YEASTMED8genetic
27708008
RRP42_YEASTRRP42genetic
27708008
LCB2_YEASTLCB2genetic
27708008
SCC4_YEASTSCC4genetic
27708008
ACT_YEASTACT1genetic
27708008
CDC20_YEASTCDC20genetic
27708008
MCE1_YEASTCEG1genetic
27708008
SWC4_YEASTSWC4genetic
27708008
ESP1_YEASTESP1genetic
27708008
RRP41_YEASTSKI6genetic
27708008
MED6_YEASTMED6genetic
27708008
ATC7_YEASTNEO1genetic
27708008
PRI1_YEASTPRI1genetic
27708008
ESS1_YEASTESS1genetic
27708008
ARP3_YEASTARP3genetic
27708008
YKT6_YEASTYKT6genetic
27708008
BET5_YEASTBET5genetic
27708008
MCM1_YEASTMCM1genetic
27708008
LIP1_YEASTLIP1genetic
27708008
MED7_YEASTMED7genetic
27708008
SMP3_YEASTSMP3genetic
27708008
STE50_YEASTSTE50genetic
27708008
RIM1_YEASTRIM1genetic
27708008
RLA1_YEASTRPP1Agenetic
27708008
S2538_YEASTYDL119Cgenetic
27708008
AIR2_YEASTAIR2genetic
27708008
VHS1_YEASTVHS1genetic
27708008
AIM11_YEASTAIM11genetic
27708008
RAD4_YEASTRAD4genetic
27708008
VAM7_YEASTVAM7genetic
27708008
YGY5_YEASTYGL235Wgenetic
27708008
RTG2_YEASTRTG2genetic
27708008
LRP1_YEASTLRP1genetic
27708008
CSN12_YEASTYJR084Wgenetic
27708008
FRE2_YEASTFRE2genetic
27708008
COX12_YEASTCOX12genetic
27708008
ERG3_YEASTERG3genetic
27708008
GYS2_YEASTGSY2genetic
27708008
YPT7_YEASTYPT7genetic
27708008
SIP5_YEASTSIP5genetic
27708008
YM8V_YEASTYMR295Cgenetic
27708008
PET8_YEASTPET8genetic
27708008
OCA2_YEASTOCA2genetic
27708008
ATG19_YEASTATG19genetic
27708008
RRP6_YEASTRRP6genetic
27708008
DIA2_YEASTDIA2genetic
27708008
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of MCFS1_YEAST

loading...

Related Literatures of Post-Translational Modification

TOP
© 2024 Institute of Bioinformatics and Systems Biology, NYCU | Designed by : BiOmics Laboratory