APD1_YEAST - dbPTM
APD1_YEAST - PTM Information in dbPTM
Basic Information of Protein
UniProt ID APD1_YEAST
UniProt AC P38281
Protein Name Actin patches distal protein 1
Gene Name APD1
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length 316
Subcellular Localization Cytoplasm . Nucleus .
Protein Description Required for normal localization of actin patches. Involved in tolerance to sodium ions and hydrogen peroxide..
Protein Sequence MAFLNIFKQKRGDEASQLSAKGREEISQSIKICKSDDAANEHSCSGDCKTEIEEGEQAFAKLKIEHETPLLNSSKTPKIHFVVPTSQIDWQHDACLEDPKSVQYKISQWCDKNSAKFSNVGTGKTLNCAVSSLPKDIMDIDVMRGTKNNVLILPYFIWLNDLRSDDVEATLDGLVPDLLDENISREKLLETRPNVAVARERAFVFICSHTTRDKRCGITAPYLKKVFDSKLQEHGLYRDNSDYRAEGVKIAFVNHVGGHKFAANVQIYLRNPNTLIWLGRVTPTIVPSIVEHLIVPEEPTLPFPEKVRCIKKYQSW
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
8AcetylationMAFLNIFKQKRGDEA
CCHHHHHCHHCCCHH		51.6325381059
29PhosphorylationGREEISQSIKICKSD
CHHHHHHHCEEECCC		21.0421440633
35PhosphorylationQSIKICKSDDAANEH
HHCEEECCCCCCCCC		35.9928889911
45PhosphorylationAANEHSCSGDCKTEI
CCCCCCCCCCCCCEE		40.4528889911
76PhosphorylationPLLNSSKTPKIHFVV
CCCCCCCCCCEEEEE		31.5921440633
187AcetylationDENISREKLLETRPN
CCCCCHHHHHHHCCC		58.2124489116
230AcetylationLKKVFDSKLQEHGLY
HHHHHCHHHHHCCCC		56.9124489116
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of APD1_YEAST !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of APD1_YEAST !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of APD1_YEAST !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
CDC37_YEASTCDC37genetic
27708008
SCC1_YEASTMCD1genetic
27708008
TCPZ_YEASTCCT6genetic
27708008
GPI19_YEASTGPI19genetic
27708008
ACT_YEASTACT1genetic
27708008
SPC97_YEASTSPC97genetic
27708008
HACD_YEASTPHS1genetic
27708008
FNTA_YEASTRAM2genetic
27708008
NTR2_YEASTNTR2genetic
27708008
CBF3B_YEASTCEP3genetic
27708008
CAP_YEASTSRV2genetic
27708008
DBP6_YEASTDBP6genetic
27708008
TYSY_YEASTCDC21genetic
27708008
CLP1_YEASTCLP1genetic
27708008
NAB3_YEASTNAB3genetic
27708008
PSB5_YEASTPRE2genetic
27708008
SEC23_YEASTSEC23genetic
27708008
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of APD1_YEAST

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Related Literatures of Post-Translational Modification

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