dbPTM

UBS1_YEAST - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	UBS1_YEAST
UniProt AC	P38290
Protein Name	Ubiquitin-conjugating enzyme suppressor 1
Gene Name	UBS1
Organism	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length	277
Subcellular Localization
Protein Description	Not known; its elevated expression suppresses the conditional cell cycle defects associated with UBC3/CDC34 mutations..
Protein Sequence	MAYSLTRKLLKDWKYFMRHPEKTQGLFHVRPHDSDLHLWHVVMYEPRTSLEVYLLLYIGGNDQDPYIIMKCLSPNCCFPINRTVSMTHLNYLLLKDLGLQDLLFHIWQPLFHIQATEDLQYSPSTVKFNRAWNRIIYKDFKSYFPELIGTLQPGDYSIVKSYSKNHNISNSNGGSVNEFMSSYNAQSHTFHAQDNSKNPYTNSSIGKSSMLSTLNNNNVNKRTHDYNAIDFMTKNLLACDDDSIHPVVSSKRSRTLACPDETNDNRGSEHYTKRKKI

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
83	Phosphorylation	CCFPINRTVSMTHLN CCCCCCCCCHHHHHH	16.67	28132839
85	Phosphorylation	FPINRTVSMTHLNYL CCCCCCCHHHHHHHH	19.83	28132839
87	Phosphorylation	INRTVSMTHLNYLLL CCCCCHHHHHHHHHH	18.72	28132839
91	Phosphorylation	VSMTHLNYLLLKDLG CHHHHHHHHHHHHCC	12.70	28132839

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of UBS1_YEAST !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of UBS1_YEAST !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of UBS1_YEAST !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
YRB1_YEAST	YRB1	genetic	10991951
UBC3_YEAST	CDC34	genetic	8552096
RPB1_YEAST	RPO21	genetic	19061648
DBP3_YEAST	DBP3	genetic	19061648
CF130_YEAST	CAF130	genetic	19061648
DOA1_YEAST	DOA1	genetic	19061648
LTV1_YEAST	LTV1	genetic	19061648
NOP12_YEAST	NOP12	genetic	19061648
RIC1_YEAST	RIC1	genetic	19061648
PRP11_YEAST	PRP11	genetic	19061648
SAP30_YEAST	SAP30	genetic	19061648
RV161_YEAST	RVS161	genetic	20093466
TPS2_YEAST	TPS2	genetic	20093466
HMO1_YEAST	HMO1	genetic	20093466
BCS1_YEAST	BCS1	genetic	20093466
RLA4_YEAST	RPP2B	genetic	20093466
RV167_YEAST	RVS167	genetic	20093466
RGD2_YEAST	RGD2	genetic	20093466
CF130_YEAST	CAF130	genetic	20093466
RL8A_YEAST	RPL8A	genetic	20093466
RPN10_YEAST	RPN10	genetic	20093466
PTK2_YEAST	PTK2	genetic	20093466
RL8B_YEAST	RPL8B	genetic	20093466
RSC2_YEAST	RSC2	genetic	20093466
NST1_YEAST	NST1	genetic	20093466
RL9B_YEAST	RPL9B	genetic	20093466
INO4_YEAST	INO4	genetic	20093466
MSS18_YEAST	MSS18	genetic	20093466
CSN12_YEAST	YJR084W	genetic	27708008
MRC1_YEAST	MRC1	genetic	27708008
RV161_YEAST	RVS161	genetic	27708008
BUD31_YEAST	BUD31	genetic	27708008
NHP10_YEAST	NHP10	genetic	27708008
UGX2_YEAST	UGX2	genetic	27708008
TPS2_YEAST	TPS2	genetic	27708008
H2A1_YEAST	HTA1	genetic	27708008
RLA4_YEAST	RPP2B	genetic	27708008
HPRT_YEAST	HPT1	genetic	27708008
RGD2_YEAST	RGD2	genetic	27708008
CF130_YEAST	CAF130	genetic	27708008
RPN10_YEAST	RPN10	genetic	27708008
RL9B_YEAST	RPL9B	genetic	27708008
GLO4_YEAST	GLO4	genetic	27708008
ALE1_YEAST	ALE1	genetic	27708008
MSS18_YEAST	MSS18	genetic	27708008

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of UBS1_YEAST

Related Literatures of Post-Translational Modification