UGX2_YEAST - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: UGX2_YEAST
• UniProt AC: P32772
• Protein Name: Protein UGX2
• Gene Name: UGX2
• Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
• Sequence Length: 223
• Protein Sequence: MEDKEKLIVYSNTSSVFTYSAEIRPNFKISVSQSQGFAWNQDLFATQYQQSYKVVYDAHEDNFDELILKIKGKLKTKSNKRAKMKSKTKLTRTAKQRRESPVCERDESDEDNDSDHYQRIQVLDGHEFPRANRYKSVWAHDVHSNEDSTSDGESNHDIDMIGGTGTSYAGAAIMDRPRRKSERSISFVEDSKTGDYRYQTGQVDVVEVDSDTPENNHLKWLIK

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
100	Phosphorylation	TAKQRRESPVCERDE HHHHHHCCCCCCCCC	22.33	19779198
108	Phosphorylation	PVCERDESDEDNDSD CCCCCCCCCCCCCCC	51.06	28889911
114	Phosphorylation	ESDEDNDSDHYQRIQ CCCCCCCCCCCEEEE	32.32	19779198
117	Phosphorylation	EDNDSDHYQRIQVLD CCCCCCCCEEEEEEC	12.41	30377154
181	Phosphorylation	MDRPRRKSERSISFV CCCCCCCCCCCCEEE	36.11	27717283
184	Phosphorylation	PRRKSERSISFVEDS CCCCCCCCCEEEECC	20.66	22369663
186	Phosphorylation	RKSERSISFVEDSKT CCCCCCCEEEECCCC	25.20	22369663
192	Ubiquitination	ISFVEDSKTGDYRYQ CEEEECCCCCCEEEE	69.70	24961812
210	Phosphorylation	VDVVEVDSDTPENNH EEEEEECCCCCCCCC	48.86	23749301

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of UGX2_YEAST !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of UGX2_YEAST !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of UGX2_YEAST !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
RAD4_YEAST	RAD4	genetic	27708008
YFH6_YEAST	YFR006W	genetic	27708008
KCC1_YEAST	CMK1	genetic	27708008
RCF2_YEAST	RCF2	genetic	27708008

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.

Related Literatures of Post-Translational Modification

Phosphorylation

"A multidimensional chromatography technology for in-depthphosphoproteome analysis.";
Albuquerque C.P., Smolka M.B., Payne S.H., Bafna V., Eng J., Zhou H.;
Mol. Cell. Proteomics 7:1389-1396(2008).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-184 AND SER-186, ANDMASS SPECTROMETRY.
PubMed: 18407956