RL4P_YEAST - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: RL4P_YEAST
• UniProt AC: P51998
• Protein Name: 54S ribosomal protein YmL6, mitochondrial
• Gene Name: YML6
• Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
• Sequence Length: 286
• Subcellular Localization: Mitochondrion . Mitoribosomes are tethered to the mitochondrial inner membrane and spatially aligned with the membrane insertion machinery through two distinct membrane contact sites, formed by the 21S rRNA expansion segment 96-ES1 and the inner memb
• Protein Description: Component of the mitochondrial ribosome (mitoribosome), a dedicated translation machinery responsible for the synthesis of mitochondrial genome-encoded proteins, including at least some of the essential transmembrane subunits of the mitochondrial respiratory chain. The mitoribosomes are attached to the mitochondrial inner membrane and translation products are cotranslationally integrated into the membrane..
• Protein Sequence: MTIKRNLVKTLQSIRYQATTATAHAESTLNPLPNAAIPPKYALVTVRSFPSLEPLTFVPVPTSTVAAPLRRDILWRAVVYENDNRRVGASNPPGRSENGFSRRKLMPQKGSGRARVGDANSPTRHNGGRALARTAPNDYTTELPSKVYSMAFNNALSHQYKSGKLFVIGGEKVDLISPTPELDLNRLDLVNTNTVEGKEIFEGEVIFRKFLEEFQLKGKRLLFITDKTREGLIKSSDPYKQKVDVIQKELVEVNDILRAQAVFIELEALEYLAMAHQKEILHSVSN

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
48	Phosphorylation	YALVTVRSFPSLEPL EEEEEEECCCCCCCC	36.85	21440633
121	Phosphorylation	ARVGDANSPTRHNGG CCCCCCCCCCCCCCC	29.39	27214570
157	Phosphorylation	MAFNNALSHQYKSGK HHHHCHHHHCCCCCC	13.21	28889911
162	Phosphorylation	ALSHQYKSGKLFVIG HHHHCCCCCCEEEEC	35.90	28889911
227	Acetylation	RLLFITDKTREGLIK EEEEEECCCCCCCCC	40.61	24489116

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of RL4P_YEAST !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of RL4P_YEAST !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of RL4P_YEAST !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
RM16_YEAST	MRPL16	physical	16554755
MNP1_YEAST	MNP1	physical	16554755
RM49_YEAST	MRP49	physical	16554755
RM13_YEAST	MRPL13	physical	16554755
RM40_YEAST	MRPL40	physical	16554755
IMG1_YEAST	IMG1	physical	16429126
MHR1_YEAST	MHR1	physical	16429126
RM41_YEAST	MRP20	physical	16429126
RM49_YEAST	MRP49	physical	16429126
RM02_YEAST	MRP7	physical	16429126
RM01_YEAST	MRPL1	physical	16429126
RM13_YEAST	MRPL13	physical	16429126
RM17_YEAST	MRPL17	physical	16429126
RM20_YEAST	MRPL20	physical	16429126
RM22_YEAST	MRPL22	physical	16429126
RM24_YEAST	MRPL24	physical	16429126
RM27_YEAST	MRPL27	physical	16429126
RM03_YEAST	MRPL3	physical	16429126
RM35_YEAST	MRPL35	physical	16429126
RM36_YEAST	MRPL36	physical	16429126
RM04_YEAST	MRPL4	physical	16429126
RM06_YEAST	MRPL6	physical	16429126
RM07_YEAST	MRPL7	physical	16429126
RM08_YEAST	MRPL8	physical	16429126
RM09_YEAST	MRPL9	physical	16429126
DED1_YEAST	DED1	physical	16429126
NIC96_YEAST	NIC96	physical	18719252

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.