| UniProt ID | SEC16_YEAST | |
|---|---|---|
| UniProt AC | P48415 | |
| Protein Name | COPII coat assembly protein SEC16 | |
| Gene Name | SEC16 | |
| Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast). | |
| Sequence Length | 2195 | |
| Subcellular Localization |
Endoplasmic reticulum membrane Peripheral membrane protein Cytoplasmic side . On the endoplasmic reticulum and on vesicles which bud from it. |
|
| Protein Description | Involved in the initiation of assembly of the COPII coat required for the formation of transport vesicles from the endoplasmic reticulum (ER) and the selection of cargo molecules. Also involved in autophagy.. | |
| Protein Sequence | MTPEAKKRKNQKKKLKQKQKKAAEKAASHSEEPLELPESTINSSFNDDSVNRTESDIASKSDVPPVSSSTNISPANETQLEIPDTQELHHKLLNDSDQHDITADSNDLPDNSIVEHDSVITQTKPAMSQEYEETAAHLSSRNPSLDVVAGELHNNNEHTQKIAVSAVEEDSFNEEEGENHDSIIISSLNDATPSQYNHFLPSDGNLLSPELSSGDTPTHNVPLGTKDNEINDDEYCNDKEISLNANNVLPDELSKEEDERLKLETHVSTEEKKQDIADQETAENLFTSSTEPSENKIRNSGDDTSMLFQDDESDQKVPWEEDVKKDFHNENTNNTQESAPNTDDRDKGYEGNEALKKSESCTAADERSYSEETSEDIFHGHDKQVVEGQNDFTGKNIENESQKLMGEGNHKLPLSAEADIIEPGKDIQDQAEDLFTQSSGDLGEVLPWESTDKNADVTSKSQEKHEDLFAASGNDEKLPWEVSDGEVSSGKTENSMQTSTEKIAEQKFSFLENDDDLLDDDDSFLASSEEEDTVPNTDNTTNLTSKPVEEKKASRYKPIIEEEAGMRQEQVHFTNTTGIVTPQQFHGLTKTGLGTPNQQVSVPNIVSPKPPVVKDNRSNFKINEEKKKSDAYDFPLEIISESSKKGHAKPVAVPTQRFGSGNSFSSLDKPIPQSRKGSNNSNRPPVIPLGTQEPRSSRTNSAISQSPVNYAFPNPYKIQQLQQAPIQSGMPLPNTNIPPPALKVETTVSAPPIRARGVSNASVGSSASFGARHATQYGLNNGVPPVSPYGQATINLPTANKYAPVSPTVQQKQYPSVVQNLGASAVNTPNFVKTHRGHTSSISSYTPNQNEHASRYAPNYQQSYQVPYTSQPVGPVAGNSSYQSQTRSSYAVPMMPQAQTSASIQPHANIQPPTGILPLAPLRPLDPLQAATNLQPRASNITAANSLPLANLPLAENILPEIITHRATSSVAPPRQENNPIKIDNEALLRRQFPIFHWSAANKVVYAVPPIPDQSQYMISSSIVQEIKVTPIDQIIKPNDMLKSFPGPLGSAKLKKKDLTKWMETTIKSISENESSTDMTIWQLLEMKLNDKVNWKNISKLLYNSDELLMYLSQPFPNGDMIPNAYRLDINCQMRVLAFLQTGNHDEALRLALSKRDYAIALLVGSLMGKDRWSEVIQKYLYEGFTAGPNDQKELAHFLLLIFQVFVGNSKMAIKSFYTNNETSQWASENWKSIVAAVLINIPENNEDPLLIPPVVLEFLIEFGIFLTKKGLTAAASTLFIIGNVPLSNEPVMADSDVIFESIGNMNTFESILWDEIYEYIFSYDPKFKGFSSILPQKIYHASLLQEQGLNSLGTKYTDYLSSSVRKLPKKDILTINLTRELSEVASRLSESNTGWLAKPKLSSVWGQLDKSFNKYIGGDDIDALNKKNDKKKVFDGFTPGSSANSSTVDLTQTFTPFQAQVTSQSYVDTTALLHNAHNVPSHSVLHSKPSNVSKGLVEANLPYTHRIGDSLQGSPQRIHNTQFAAAEPQMASLRRVRTDQHTNEKALKSQQILEKKSTAYTPQFGQNHSVPMEKSNSNVPSLFADFPAPPKLGTVPSNYVSSPDLVRRESIISTGSEFLPPPKIGVPTKANSSQGSLMYSPSVEALPIDPVVPQVHETGYNDFGNKHSQKSMPEDESHTSHDNSNADQNTLKDSADVTDETMDIEGPGFNDVKNLLPMEPNHQPTSTVNPIQTISDDIQPILQTNVEVRGTDASKMENSLPSIENERSSEEQPENISKSASSAYLPSTGGLSLENRPLTQDENSISETVQSTYLPAGSISMEAKPISQVQDVPRNVNNKASKLVEQHMAPPKPKSTDATKMNYSPYVPQSTAASADGDESTILKTSPAIYARTHQAHASNPSQYFPLVNQANETASFELSESTSQAQSNGNVASENRFSPIKKAEVVEKDTFQPTIRKASTNQYRAFKPLESDADKYNDVIEDESDDDNMSTDEAKNRKEEKKNVNMKKETKPSNKDIDDKSNGWFGWLKKDTGDKKVYKAKLGHKNTLYYDEKLKRWVNKDATEEEKQKIIESSAPPPPPIVKRKDGGPKTKPRSGPINNSLPPVHATSVIPNNPITGEPLPIKTSPSPTGPNPNNSPSPSSPISRISGVNLTSKKANGLDDLLSLAGGPKPASTRRKKKTARGYVNVMDNIQ | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 28 | Phosphorylation | KAAEKAASHSEEPLE HHHHHHHHCCCCCCC | 32.19 | 22369663 | |
| 30 | Phosphorylation | AEKAASHSEEPLELP HHHHHHCCCCCCCCC | 40.95 | 22369663 | |
| 39 | Phosphorylation | EPLELPESTINSSFN CCCCCCHHHHCCCCC | 32.42 | 22369663 | |
| 40 | Phosphorylation | PLELPESTINSSFND CCCCCHHHHCCCCCC | 23.63 | 22369663 | |
| 43 | Phosphorylation | LPESTINSSFNDDSV CCHHHHCCCCCCCCC | 32.24 | 25521595 | |
| 44 | Phosphorylation | PESTINSSFNDDSVN CHHHHCCCCCCCCCC | 24.47 | 25521595 | |
| 49 | Phosphorylation | NSSFNDDSVNRTESD CCCCCCCCCCCCHHH | 24.93 | 22369663 | |
| 53 | Phosphorylation | NDDSVNRTESDIASK CCCCCCCCHHHHHCC | 34.34 | 22369663 | |
| 55 | Phosphorylation | DSVNRTESDIASKSD CCCCCCHHHHHCCCC | 33.43 | 20377248 | |
| 59 | Phosphorylation | RTESDIASKSDVPPV CCHHHHHCCCCCCCC | 32.78 | 20377248 | |
| 61 | Phosphorylation | ESDIASKSDVPPVSS HHHHHCCCCCCCCCC | 41.15 | 19795423 | |
| 67 | Phosphorylation | KSDVPPVSSSTNISP CCCCCCCCCCCCCCC | 25.09 | 22369663 | |
| 68 | Phosphorylation | SDVPPVSSSTNISPA CCCCCCCCCCCCCCC | 41.22 | 22369663 | |
| 69 | Phosphorylation | DVPPVSSSTNISPAN CCCCCCCCCCCCCCC | 20.26 | 22369663 | |
| 70 | Phosphorylation | VPPVSSSTNISPANE CCCCCCCCCCCCCCC | 38.22 | 22369663 | |
| 73 | Phosphorylation | VSSSTNISPANETQL CCCCCCCCCCCCCCC | 21.74 | 22369663 | |
| 78 | Phosphorylation | NISPANETQLEIPDT CCCCCCCCCCCCCCH | 37.96 | 22369663 | |
| 85 | Phosphorylation | TQLEIPDTQELHHKL CCCCCCCHHHHHHHH | 20.70 | 22369663 | |
| 96 | Phosphorylation | HHKLLNDSDQHDITA HHHHCCCCCCCCCCC | 37.79 | 22369663 | |
| 102 | Phosphorylation | DSDQHDITADSNDLP CCCCCCCCCCCCCCC | 30.39 | 21440633 | |
| 105 | Phosphorylation | QHDITADSNDLPDNS CCCCCCCCCCCCCCC | 29.76 | 21551504 | |
| 112 | Phosphorylation | SNDLPDNSIVEHDSV CCCCCCCCCCCCCCE | 35.08 | 21551504 | |
| 118 | Phosphorylation | NSIVEHDSVITQTKP CCCCCCCCEECCCCC | 19.82 | 21551504 | |
| 131 | Phosphorylation | KPAMSQEYEETAAHL CCCCCHHHHHHHHHH | 16.07 | 20377248 | |
| 134 | Phosphorylation | MSQEYEETAAHLSSR CCHHHHHHHHHHHCC | 19.73 | 20377248 | |
| 140 | Phosphorylation | ETAAHLSSRNPSLDV HHHHHHHCCCCCHHE | 42.30 | 20377248 | |
| 144 | Phosphorylation | HLSSRNPSLDVVAGE HHHCCCCCHHEEEEE | 40.53 | 21082442 | |
| 242 | Phosphorylation | YCNDKEISLNANNVL CCCCCEEECCCCCCC | 19.36 | 22369663 | |
| 254 | Phosphorylation | NVLPDELSKEEDERL CCCCHHHCHHHHHHH | 35.65 | 24961812 | |
| 265 | Phosphorylation | DERLKLETHVSTEEK HHHHHHHHHCCHHHH | 37.70 | 22369663 | |
| 268 | Phosphorylation | LKLETHVSTEEKKQD HHHHHHCCHHHHHHH | 23.61 | 22369663 | |
| 269 | Phosphorylation | KLETHVSTEEKKQDI HHHHHCCHHHHHHHH | 47.26 | 22369663 | |
| 281 | Phosphorylation | QDIADQETAENLFTS HHHCCHHHHHHHHCC | 33.37 | 22369663 | |
| 287 | Phosphorylation | ETAENLFTSSTEPSE HHHHHHHCCCCCCCC | 25.57 | 22369663 | |
| 288 | Phosphorylation | TAENLFTSSTEPSEN HHHHHHCCCCCCCCC | 28.12 | 22369663 | |
| 289 | Phosphorylation | AENLFTSSTEPSENK HHHHHCCCCCCCCCC | 33.46 | 19779198 | |
| 290 | Phosphorylation | ENLFTSSTEPSENKI HHHHCCCCCCCCCCC | 52.24 | 20377248 | |
| 293 | Phosphorylation | FTSSTEPSENKIRNS HCCCCCCCCCCCCCC | 47.79 | 22369663 | |
| 300 | Phosphorylation | SENKIRNSGDDTSML CCCCCCCCCCCCCCC | 33.48 | 21440633 | |
| 304 | Phosphorylation | IRNSGDDTSMLFQDD CCCCCCCCCCCCCCC | 22.30 | 21440633 | |
| 305 | Phosphorylation | RNSGDDTSMLFQDDE CCCCCCCCCCCCCCC | 22.08 | 25521595 | |
| 313 | Phosphorylation | MLFQDDESDQKVPWE CCCCCCCCCCCCCCH | 52.95 | 22369663 | |
| 335 | Phosphorylation | HNENTNNTQESAPNT CCCCCCCCCCCCCCC | 35.46 | 24961812 | |
| 338 | Phosphorylation | NTNNTQESAPNTDDR CCCCCCCCCCCCCCC | 38.93 | 20377248 | |
| 342 | Phosphorylation | TQESAPNTDDRDKGY CCCCCCCCCCCCCCC | 37.91 | 20377248 | |
| 349 | Phosphorylation | TDDRDKGYEGNEALK CCCCCCCCCHHHHHH | 26.80 | 27017623 | |
| 358 | Phosphorylation | GNEALKKSESCTAAD HHHHHHHHHCCCCCC | 32.91 | 19823750 | |
| 360 | Phosphorylation | EALKKSESCTAADER HHHHHHHCCCCCCCC | 24.69 | 20377248 | |
| 362 | Phosphorylation | LKKSESCTAADERSY HHHHHCCCCCCCCCC | 33.87 | 20377248 | |
| 368 | Phosphorylation | CTAADERSYSEETSE CCCCCCCCCCCCCCC | 30.85 | 22369663 | |
| 369 | Phosphorylation | TAADERSYSEETSED CCCCCCCCCCCCCCC | 26.73 | 22369663 | |
| 370 | Phosphorylation | AADERSYSEETSEDI CCCCCCCCCCCCCCC | 30.15 | 22369663 | |
| 373 | Phosphorylation | ERSYSEETSEDIFHG CCCCCCCCCCCCCCC | 33.11 | 22369663 | |
| 374 | Phosphorylation | RSYSEETSEDIFHGH CCCCCCCCCCCCCCC | 36.23 | 22369663 | |
| 383 | Acetylation | DIFHGHDKQVVEGQN CCCCCCCHHHCCCCC | 39.04 | 24489116 | |
| 395 | Acetylation | GQNDFTGKNIENESQ CCCCCCCCCCCHHHH | 52.25 | 24489116 | |
| 395 | Ubiquitination | GQNDFTGKNIENESQ CCCCCCCCCCCHHHH | 52.25 | 23749301 | |
| 401 | Phosphorylation | GKNIENESQKLMGEG CCCCCHHHHHHCCCC | 44.17 | 28889911 | |
| 403 | Acetylation | NIENESQKLMGEGNH CCCHHHHHHCCCCCC | 50.12 | 24489116 | |
| 415 | Phosphorylation | GNHKLPLSAEADIIE CCCCCCCCCCCCEEC | 23.32 | 24961812 | |
| 436 | Phosphorylation | DQAEDLFTQSSGDLG HHHHHHHHCCCCCCC | 34.53 | 21551504 | |
| 438 | Phosphorylation | AEDLFTQSSGDLGEV HHHHHHCCCCCCCCC | 32.98 | 21440633 | |
| 439 | Phosphorylation | EDLFTQSSGDLGEVL HHHHHCCCCCCCCCC | 26.89 | 21440633 | |
| 458 | Phosphorylation | TDKNADVTSKSQEKH CCCCCCCCCHHHHHH | 30.86 | 21551504 | |
| 459 | Phosphorylation | DKNADVTSKSQEKHE CCCCCCCCHHHHHHH | 30.11 | 21551504 | |
| 461 | Phosphorylation | NADVTSKSQEKHEDL CCCCCCHHHHHHHHH | 43.25 | 25704821 | |
| 472 | Phosphorylation | HEDLFAASGNDEKLP HHHHHHHCCCCCCCC | 34.40 | 22369663 | |
| 483 | Phosphorylation | EKLPWEVSDGEVSSG CCCCCEECCCCCCCC | 28.51 | 22369663 | |
| 488 | Phosphorylation | EVSDGEVSSGKTENS EECCCCCCCCCCCCC | 29.13 | 22369663 | |
| 489 | Phosphorylation | VSDGEVSSGKTENSM ECCCCCCCCCCCCCC | 49.86 | 22890988 | |
| 492 | Phosphorylation | GEVSSGKTENSMQTS CCCCCCCCCCCCCCC | 43.88 | 20377248 | |
| 495 | Phosphorylation | SSGKTENSMQTSTEK CCCCCCCCCCCCHHH | 13.16 | 22369663 | |
| 498 | Phosphorylation | KTENSMQTSTEKIAE CCCCCCCCCHHHHHH | 29.04 | 22369663 | |
| 499 | Phosphorylation | TENSMQTSTEKIAEQ CCCCCCCCHHHHHHH | 20.06 | 22369663 | |
| 500 | Phosphorylation | ENSMQTSTEKIAEQK CCCCCCCHHHHHHHH | 44.69 | 19795423 | |
| 502 | Ubiquitination | SMQTSTEKIAEQKFS CCCCCHHHHHHHHHH | 47.51 | 23749301 | |
| 509 | Phosphorylation | KIAEQKFSFLENDDD HHHHHHHHHHCCCCC | 35.64 | 19795423 | |
| 523 | Phosphorylation | DLLDDDDSFLASSEE CCCCCCCCCCCCCCC | 29.20 | 21551504 | |
| 527 | Phosphorylation | DDDSFLASSEEEDTV CCCCCCCCCCCCCCC | 40.19 | 19823750 | |
| 528 | Phosphorylation | DDSFLASSEEEDTVP CCCCCCCCCCCCCCC | 43.34 | 19823750 | |
| 533 | Phosphorylation | ASSEEEDTVPNTDNT CCCCCCCCCCCCCCC | 40.94 | 21551504 | |
| 537 | Phosphorylation | EEDTVPNTDNTTNLT CCCCCCCCCCCCCCC | 25.26 | 19823750 | |
| 540 | Phosphorylation | TVPNTDNTTNLTSKP CCCCCCCCCCCCCCC | 21.63 | 19823750 | |
| 541 | Phosphorylation | VPNTDNTTNLTSKPV CCCCCCCCCCCCCCH | 34.19 | 19823750 | |
| 544 | Phosphorylation | TDNTTNLTSKPVEEK CCCCCCCCCCCHHHH | 36.45 | 19823750 | |
| 545 | Phosphorylation | DNTTNLTSKPVEEKK CCCCCCCCCCHHHHH | 37.82 | 19823750 | |
| 591 | Phosphorylation | QFHGLTKTGLGTPNQ HHCCCCCCCCCCCCC | 32.19 | 22890988 | |
| 595 | Phosphorylation | LTKTGLGTPNQQVSV CCCCCCCCCCCEECC | 24.90 | 22369663 | |
| 601 | Phosphorylation | GTPNQQVSVPNIVSP CCCCCEECCCCCCCC | 27.76 | 22890988 | |
| 607 | Phosphorylation | VSVPNIVSPKPPVVK ECCCCCCCCCCCCCC | 24.33 | 22369663 | |
| 629 | Phosphorylation | INEEKKKSDAYDFPL CCCHHHHCCCCCCCH | 36.03 | 19795423 | |
| 632 | Phosphorylation | EKKKSDAYDFPLEII HHHHCCCCCCCHHHH | 24.09 | 19779198 | |
| 640 | Phosphorylation | DFPLEIISESSKKGH CCCHHHHCCCCCCCC | 36.77 | 19823750 | |
| 642 | Phosphorylation | PLEIISESSKKGHAK CHHHHCCCCCCCCCC | 40.44 | 19823750 | |
| 643 | Phosphorylation | LEIISESSKKGHAKP HHHHCCCCCCCCCCC | 34.04 | 19823750 | |
| 655 | Phosphorylation | AKPVAVPTQRFGSGN CCCCCCCCCCCCCCC | 26.27 | 20377248 | |
| 660 | Phosphorylation | VPTQRFGSGNSFSSL CCCCCCCCCCCCCCC | 31.89 | 22369663 | |
| 663 | Phosphorylation | QRFGSGNSFSSLDKP CCCCCCCCCCCCCCC | 29.99 | 22369663 | |
| 665 | Phosphorylation | FGSGNSFSSLDKPIP CCCCCCCCCCCCCCC | 29.79 | 22369663 | |
| 666 | Phosphorylation | GSGNSFSSLDKPIPQ CCCCCCCCCCCCCCC | 38.28 | 22369663 | |
| 669 | Acetylation | NSFSSLDKPIPQSRK CCCCCCCCCCCCCCC | 50.57 | 24489116 | |
| 674 | Phosphorylation | LDKPIPQSRKGSNNS CCCCCCCCCCCCCCC | 30.52 | 22369663 | |
| 678 | Phosphorylation | IPQSRKGSNNSNRPP CCCCCCCCCCCCCCC | 35.55 | 22369663 | |
| 681 | Phosphorylation | SRKGSNNSNRPPVIP CCCCCCCCCCCCCCC | 38.17 | 22369663 | |
| 691 | Phosphorylation | PPVIPLGTQEPRSSR CCCCCCCCCCCCCCC | 37.13 | 22369663 | |
| 696 | Phosphorylation | LGTQEPRSSRTNSAI CCCCCCCCCCCCCCC | 34.58 | 22369663 | |
| 697 | Phosphorylation | GTQEPRSSRTNSAIS CCCCCCCCCCCCCCC | 44.39 | 20377248 | |
| 699 | Phosphorylation | QEPRSSRTNSAISQS CCCCCCCCCCCCCCC | 35.16 | 22369663 | |
| 701 | Phosphorylation | PRSSRTNSAISQSPV CCCCCCCCCCCCCCC | 26.77 | 22369663 | |
| 704 | Phosphorylation | SRTNSAISQSPVNYA CCCCCCCCCCCCCCC | 25.07 | 22369663 | |
| 706 | Phosphorylation | TNSAISQSPVNYAFP CCCCCCCCCCCCCCC | 24.83 | 22369663 | |
| 710 | Phosphorylation | ISQSPVNYAFPNPYK CCCCCCCCCCCCCCC | 15.17 | 22890988 | |
| 716 | Phosphorylation | NYAFPNPYKIQQLQQ CCCCCCCCCHHHHHH | 27.62 | 22369663 | |
| 746 | Phosphorylation | PPALKVETTVSAPPI CCCCEEEEEEECCCC | 35.17 | 22369663 | |
| 747 | Phosphorylation | PALKVETTVSAPPIR CCCEEEEEEECCCCE | 10.04 | 22369663 | |
| 749 | Phosphorylation | LKVETTVSAPPIRAR CEEEEEEECCCCEEC | 32.72 | 22369663 | |
| 759 | Phosphorylation | PIRARGVSNASVGSS CCEECCCCCCCCCCC | 29.51 | 22369663 | |
| 762 | Phosphorylation | ARGVSNASVGSSASF ECCCCCCCCCCCHHH | 31.12 | 22369663 | |
| 765 | Phosphorylation | VSNASVGSSASFGAR CCCCCCCCCHHHCHH | 22.15 | 22369663 | |
| 766 | Phosphorylation | SNASVGSSASFGARH CCCCCCCCHHHCHHH | 23.23 | 22369663 | |
| 768 | Phosphorylation | ASVGSSASFGARHAT CCCCCCHHHCHHHHH | 26.59 | 22369663 | |
| 777 | Phosphorylation | GARHATQYGLNNGVP CHHHHHHHCCCCCCC | 21.16 | 22369663 | |
| 787 | Phosphorylation | NNGVPPVSPYGQATI CCCCCCCCCCCEEEE | 20.41 | 22369663 | |
| 789 | Phosphorylation | GVPPVSPYGQATINL CCCCCCCCCEEEEEC | 17.86 | 22369663 | |
| 793 | Phosphorylation | VSPYGQATINLPTAN CCCCCEEEEECCCCC | 11.51 | 21082442 | |
| 802 | Phosphorylation | NLPTANKYAPVSPTV ECCCCCCCCCCCCCC | 18.88 | 22890988 | |
| 806 | Phosphorylation | ANKYAPVSPTVQQKQ CCCCCCCCCCCCHHH | 17.50 | 22369663 | |
| 808 | Phosphorylation | KYAPVSPTVQQKQYP CCCCCCCCCCHHHCC | 24.36 | 22369663 | |
| 824 | Phosphorylation | VVQNLGASAVNTPNF HHHHCCCCCCCCCCC | 30.83 | 19684113 | |
| 828 | Phosphorylation | LGASAVNTPNFVKTH CCCCCCCCCCCEEEC | 17.01 | 19684113 | |
| 833 | Acetylation | VNTPNFVKTHRGHTS CCCCCCEEECCCCCC | 34.18 | 24489116 | |
| 839 | Phosphorylation | VKTHRGHTSSISSYT EEECCCCCCCCCCCC | 27.30 | 22890988 | |
| 840 | Phosphorylation | KTHRGHTSSISSYTP EECCCCCCCCCCCCC | 21.72 | 17330950 | |
| 841 | Phosphorylation | THRGHTSSISSYTPN ECCCCCCCCCCCCCC | 27.87 | 17330950 | |
| 843 | Phosphorylation | RGHTSSISSYTPNQN CCCCCCCCCCCCCCC | 21.17 | 17330950 | |
| 844 | Phosphorylation | GHTSSISSYTPNQNE CCCCCCCCCCCCCCC | 31.21 | 22890988 | |
| 845 | Phosphorylation | HTSSISSYTPNQNEH CCCCCCCCCCCCCCC | 21.30 | 22890988 | |
| 846 | Phosphorylation | TSSISSYTPNQNEHA CCCCCCCCCCCCCCH | 20.08 | 22890988 | |
| 939 | Phosphorylation | TNLQPRASNITAANS HCCCCCCCCCCCCCC | 30.00 | 28889911 | |
| 968 | Phosphorylation | EIITHRATSSVAPPR HHHHCCCCCCCCCCC | 22.84 | 22369663 | |
| 969 | Phosphorylation | IITHRATSSVAPPRQ HHHCCCCCCCCCCCC | 23.10 | 22369663 | |
| 970 | Phosphorylation | ITHRATSSVAPPRQE HHCCCCCCCCCCCCC | 20.24 | 24930733 | |
| 1061 | Acetylation | LKKKDLTKWMETTIK CCHHHHHHHHHHHHH | 52.41 | 24489116 | |
| 1065 | Phosphorylation | DLTKWMETTIKSISE HHHHHHHHHHHHHHC | 20.09 | 27017623 | |
| 1158 | Phosphorylation | LALSKRDYAIALLVG HHHHHHHHHHHHHHH | 12.16 | 19795423 | |
| 1166 | Phosphorylation | AIALLVGSLMGKDRW HHHHHHHHHHCCCHH | 14.01 | 19823750 | |
| 1357 | Phosphorylation | LNSLGTKYTDYLSSS HHHCCCHHHHHHHHH | 12.51 | 21440633 | |
| 1375 | Phosphorylation | LPKKDILTINLTREL CCHHCEEEEECCHHH | 14.25 | 22369663 | |
| 1379 | Phosphorylation | DILTINLTRELSEVA CEEEEECCHHHHHHH | 20.01 | 22369663 | |
| 1383 | Phosphorylation | INLTRELSEVASRLS EECCHHHHHHHHHHH | 25.85 | 25752575 | |
| 1399 | Acetylation | SNTGWLAKPKLSSVW CCCCCCCCHHHHHHH | 40.28 | 24489116 | |
| 1403 | Phosphorylation | WLAKPKLSSVWGQLD CCCCHHHHHHHHHHC | 29.04 | 22369663 | |
| 1404 | Phosphorylation | LAKPKLSSVWGQLDK CCCHHHHHHHHHHCH | 32.12 | 20377248 | |
| 1411 | Acetylation | SVWGQLDKSFNKYIG HHHHHHCHHHHHHCC | 66.59 | 24489116 | |
| 1412 | Phosphorylation | VWGQLDKSFNKYIGG HHHHHCHHHHHHCCC | 33.45 | 30377154 | |
| 1415 | Acetylation | QLDKSFNKYIGGDDI HHCHHHHHHCCCCCH | 35.91 | 24489116 | |
| 1464 | Phosphorylation | PFQAQVTSQSYVDTT CCEEEECCCCCCCHH | 20.48 | 28889911 | |
| 1466 | Phosphorylation | QAQVTSQSYVDTTAL EEEECCCCCCCHHHH | 27.22 | 28889911 | |
| 1504 | Phosphorylation | LVEANLPYTHRIGDS CHHCCCCCCCCCCCC | 20.53 | 22369663 | |
| 1505 | Phosphorylation | VEANLPYTHRIGDSL HHCCCCCCCCCCCCC | 11.62 | 22369663 | |
| 1511 | Phosphorylation | YTHRIGDSLQGSPQR CCCCCCCCCCCCCCE | 19.85 | 22369663 | |
| 1515 | Phosphorylation | IGDSLQGSPQRIHNT CCCCCCCCCCEECCC | 12.61 | 22369663 | |
| 1522 | Phosphorylation | SPQRIHNTQFAAAEP CCCEECCCHHHHCCH | 15.76 | 28889911 | |
| 1539 | Phosphorylation | ASLRRVRTDQHTNEK HHHHHHHCCHHHCHH | 36.83 | 28889911 | |
| 1546 | Acetylation | TDQHTNEKALKSQQI CCHHHCHHHHHHHHH | 62.17 | 24489116 | |
| 1550 | Phosphorylation | TNEKALKSQQILEKK HCHHHHHHHHHHHHH | 28.32 | 23749301 | |
| 1558 | Phosphorylation | QQILEKKSTAYTPQF HHHHHHHCCCCCCCC | 29.36 | 21440633 | |
| 1559 | Phosphorylation | QILEKKSTAYTPQFG HHHHHHCCCCCCCCC | 32.34 | 21440633 | |
| 1561 | Phosphorylation | LEKKSTAYTPQFGQN HHHHCCCCCCCCCCC | 21.02 | 23607784 | |
| 1562 | Phosphorylation | EKKSTAYTPQFGQNH HHHCCCCCCCCCCCC | 14.24 | 23607784 | |
| 1570 | Phosphorylation | PQFGQNHSVPMEKSN CCCCCCCCCCCCCCC | 35.15 | 23607784 | |
| 1576 | Phosphorylation | HSVPMEKSNSNVPSL CCCCCCCCCCCCCCH | 31.98 | 22369663 | |
| 1578 | Phosphorylation | VPMEKSNSNVPSLFA CCCCCCCCCCCCHHC | 46.42 | 25521595 | |
| 1582 | Phosphorylation | KSNSNVPSLFADFPA CCCCCCCCHHCCCCC | 31.66 | 22890988 | |
| 1595 | Phosphorylation | PAPPKLGTVPSNYVS CCCCCCCCCCCCCCC | 39.41 | 22890988 | |
| 1598 | Phosphorylation | PKLGTVPSNYVSSPD CCCCCCCCCCCCCHH | 36.13 | 22369663 | |
| 1600 | Phosphorylation | LGTVPSNYVSSPDLV CCCCCCCCCCCHHHH | 13.17 | 22890988 | |
| 1602 | Phosphorylation | TVPSNYVSSPDLVRR CCCCCCCCCHHHHCC | 26.28 | 22369663 | |
| 1603 | Phosphorylation | VPSNYVSSPDLVRRE CCCCCCCCHHHHCCH | 16.64 | 22369663 | |
| 1611 | Phosphorylation | PDLVRRESIISTGSE HHHHCCHHHHCCCCC | 24.34 | 22369663 | |
| 1614 | Phosphorylation | VRRESIISTGSEFLP HCCHHHHCCCCCCCC | 25.66 | 22369663 | |
| 1615 | Phosphorylation | RRESIISTGSEFLPP CCHHHHCCCCCCCCC | 34.03 | 22369663 | |
| 1617 | Phosphorylation | ESIISTGSEFLPPPK HHHHCCCCCCCCCCC | 25.84 | 22369663 | |
| 1633 | Phosphorylation | GVPTKANSSQGSLMY CCCCCCCCCCCCCCC | 28.97 | 28152593 | |
| 1634 | Phosphorylation | VPTKANSSQGSLMYS CCCCCCCCCCCCCCC | 38.07 | 20377248 | |
| 1637 | Phosphorylation | KANSSQGSLMYSPSV CCCCCCCCCCCCCCC | 11.43 | 20377248 | |
| 1640 | Phosphorylation | SSQGSLMYSPSVEAL CCCCCCCCCCCCEEC | 23.79 | 21440633 | |
| 1641 | Phosphorylation | SQGSLMYSPSVEALP CCCCCCCCCCCEECC | 9.20 | 20377248 | |
| 1643 | Phosphorylation | GSLMYSPSVEALPID CCCCCCCCCEECCCC | 27.01 | 20377248 | |
| 1659 | Phosphorylation | VVPQVHETGYNDFGN CCCCCCCCCCCCCCC | 30.04 | 19779198 | |
| 1661 | Phosphorylation | PQVHETGYNDFGNKH CCCCCCCCCCCCCCC | 20.98 | 19779198 | |
| 1672 | Phosphorylation | GNKHSQKSMPEDESH CCCCCCCCCCCCCCC | 31.75 | 21551504 | |
| 1678 | Phosphorylation | KSMPEDESHTSHDNS CCCCCCCCCCCCCCC | 44.37 | 20377248 | |
| 1680 | Phosphorylation | MPEDESHTSHDNSNA CCCCCCCCCCCCCCC | 36.72 | 20377248 | |
| 1681 | Phosphorylation | PEDESHTSHDNSNAD CCCCCCCCCCCCCCC | 24.34 | 20377248 | |
| 1685 | Phosphorylation | SHTSHDNSNADQNTL CCCCCCCCCCCHHHC | 39.18 | 20377248 | |
| 1691 | Phosphorylation | NSNADQNTLKDSADV CCCCCHHHCCCHHCC | 29.56 | 21551504 | |
| 1699 | Phosphorylation | LKDSADVTDETMDIE CCCHHCCCCCCCCCC | 28.76 | 24961812 | |
| 1702 | Phosphorylation | SADVTDETMDIEGPG HHCCCCCCCCCCCCC | 23.97 | 28889911 | |
| 1760 | Phosphorylation | DASKMENSLPSIENE CHHHHHHCCCCCCCC | 28.49 | 20377248 | |
| 1763 | Phosphorylation | KMENSLPSIENERSS HHHHCCCCCCCCCCC | 48.07 | 22369663 | |
| 1769 | Phosphorylation | PSIENERSSEEQPEN CCCCCCCCCCCCCCC | 35.60 | 22369663 | |
| 1770 | Phosphorylation | SIENERSSEEQPENI CCCCCCCCCCCCCCC | 51.91 | 22369663 | |
| 1778 | Phosphorylation | EEQPENISKSASSAY CCCCCCCCHHHHCCC | 31.94 | 22369663 | |
| 1780 | Phosphorylation | QPENISKSASSAYLP CCCCCCHHHHCCCCC | 26.96 | 21551504 | |
| 1783 | Phosphorylation | NISKSASSAYLPSTG CCCHHHHCCCCCCCC | 22.20 | 27017623 | |
| 1856 | Phosphorylation | MAPPKPKSTDATKMN CCCCCCCCCCCCCCC | 39.79 | 21440633 | |
| 1857 | Phosphorylation | APPKPKSTDATKMNY CCCCCCCCCCCCCCC | 35.46 | 21440633 | |
| 1872 | Phosphorylation | SPYVPQSTAASADGD CCCCCHHHCCCCCCC | 22.46 | 24961812 | |
| 1875 | Phosphorylation | VPQSTAASADGDEST CCHHHCCCCCCCCCC | 25.16 | 25752575 | |
| 1881 | Phosphorylation | ASADGDESTILKTSP CCCCCCCCCCCCCCC | 26.03 | 24961812 | |
| 1882 | Phosphorylation | SADGDESTILKTSPA CCCCCCCCCCCCCCC | 28.42 | 24961812 | |
| 1886 | Phosphorylation | DESTILKTSPAIYAR CCCCCCCCCCCHHHH | 36.18 | 21440633 | |
| 1887 | Phosphorylation | ESTILKTSPAIYART CCCCCCCCCCHHHHC | 15.67 | 25752575 | |
| 1950 | Acetylation | KKAEVVEKDTFQPTI CCCEEECCCCCCCCE | 50.92 | 24489116 | |
| 1961 | Phosphorylation | QPTIRKASTNQYRAF CCCEECCCCCCCEEC | 30.81 | 25521595 | |
| 1962 | Phosphorylation | PTIRKASTNQYRAFK CCEECCCCCCCEECC | 31.07 | 25521595 | |
| 1965 | Phosphorylation | RKASTNQYRAFKPLE ECCCCCCCEECCCCC | 13.13 | 20377248 | |
| 1973 | Phosphorylation | RAFKPLESDADKYND EECCCCCCCHHHCCC | 45.86 | 22369663 | |
| 1978 | Phosphorylation | LESDADKYNDVIEDE CCCCHHHCCCCCCCC | 19.69 | 22369663 | |
| 1986 | Phosphorylation | NDVIEDESDDDNMST CCCCCCCCCCCCCCH | 59.67 | 22369663 | |
| 1992 | Phosphorylation | ESDDDNMSTDEAKNR CCCCCCCCHHHHHHH | 38.67 | 22369663 | |
| 1993 | Phosphorylation | SDDDNMSTDEAKNRK CCCCCCCHHHHHHHH | 27.39 | 22369663 | |
| 2023 | Phosphorylation | NKDIDDKSNGWFGWL CCCCCCCCCCCEEEE | 47.79 | 21440633 | |
| 2049 | Phosphorylation | AKLGHKNTLYYDEKL ECCCCCCCCCHHHHH | 22.42 | 20377248 | |
| 2055 | Acetylation | NTLYYDEKLKRWVNK CCCCHHHHHHHHHCC | 57.31 | 24489116 | |
| 2075 | Phosphorylation | EKQKIIESSAPPPPP HHHHHHHCCCCCCCC | 22.76 | 28889911 | |
| 2076 | Phosphorylation | KQKIIESSAPPPPPI HHHHHHCCCCCCCCC | 31.82 | 28889911 | |
| 2127 | Phosphorylation | GEPLPIKTSPSPTGP CCCCCCCCCCCCCCC | 46.73 | 22369663 | |
| 2128 | Phosphorylation | EPLPIKTSPSPTGPN CCCCCCCCCCCCCCC | 20.55 | 22369663 | |
| 2130 | Phosphorylation | LPIKTSPSPTGPNPN CCCCCCCCCCCCCCC | 34.56 | 25521595 | |
| 2132 | Phosphorylation | IKTSPSPTGPNPNNS CCCCCCCCCCCCCCC | 70.39 | 22369663 | |
| 2139 | Phosphorylation | TGPNPNNSPSPSSPI CCCCCCCCCCCCCCC | 33.14 | 22369663 | |
| 2141 | Phosphorylation | PNPNNSPSPSSPISR CCCCCCCCCCCCCHH | 36.92 | 22369663 | |
| 2143 | Phosphorylation | PNNSPSPSSPISRIS CCCCCCCCCCCHHCC | 53.75 | 25521595 | |
| 2144 | Phosphorylation | NNSPSPSSPISRISG CCCCCCCCCCHHCCC | 29.63 | 22369663 | |
| 2147 | Phosphorylation | PSPSSPISRISGVNL CCCCCCCHHCCCCCC | 27.26 | 22369663 | |
| 2150 | Phosphorylation | SSPISRISGVNLTSK CCCCHHCCCCCCCCC | 35.26 | 22369663 | |
| 2155 | Phosphorylation | RISGVNLTSKKANGL HCCCCCCCCCCCCCH | 33.04 | 20377248 | |
| 2156 | Phosphorylation | ISGVNLTSKKANGLD CCCCCCCCCCCCCHH | 35.01 | 22369663 | |
| 2167 | Phosphorylation | NGLDDLLSLAGGPKP CCHHHHHHHCCCCCC | 24.38 | 21551504 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of SEC16_YEAST !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of SEC16_YEAST !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of SEC16_YEAST !! | ||||||
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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| Phosphorylation | |
| Reference | PubMed |
| "A multidimensional chromatography technology for in-depthphosphoproteome analysis."; Albuquerque C.P., Smolka M.B., Payne S.H., Bafna V., Eng J., Zhou H.; Mol. Cell. Proteomics 7:1389-1396(2008). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-28; SER-30; SER-44;SER-59; SER-73; SER-144; SER-268; THR-269; SER-313; SER-360; SER-370;SER-499; SER-607; SER-660; SER-663; SER-674; SER-678; SER-681;SER-701; SER-704; SER-706; TYR-710; SER-759; SER-762; SER-765;SER-766; SER-768; SER-787; TYR-789; SER-806; THR-808; SER-1383;SER-1403; SER-1464; SER-1466; SER-1511; SER-1515; SER-1576; SER-1578;SER-1602; SER-1603; SER-1611; SER-1614; THR-1615; SER-1617; SER-1633;SER-1634; SER-1641; SER-1760; SER-1769; SER-1778; SER-1875; SER-1986;SER-1992; SER-2130; THR-2132; SER-2141 AND SER-2144, AND MASSSPECTROMETRY. | |
| "Proteome-wide identification of in vivo targets of DNA damagecheckpoint kinases."; Smolka M.B., Albuquerque C.P., Chen S.H., Zhou H.; Proc. Natl. Acad. Sci. U.S.A. 104:10364-10369(2007). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-28; SER-30; SER-268;SER-370; THR-373; SER-607; SER-663; SER-665; SER-674; SER-678;SER-787; SER-1602 AND SER-1603, AND MASS SPECTROMETRY. | |
| "Large-scale phosphorylation analysis of alpha-factor-arrestedSaccharomyces cerevisiae."; Li X., Gerber S.A., Rudner A.D., Beausoleil S.A., Haas W., Villen J.,Elias J.E., Gygi S.P.; J. Proteome Res. 6:1190-1197(2007). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-483; SER-674; SER-704;SER-706; SER-759; SER-762; SER-765; SER-843; SER-1511; SER-1515;SER-1603; SER-1611; SER-1986 AND THR-2049, AND MASS SPECTROMETRY. | |
| "Quantitative phosphoproteomics applied to the yeast pheromonesignaling pathway."; Gruhler A., Olsen J.V., Mohammed S., Mortensen P., Faergeman N.J.,Mann M., Jensen O.N.; Mol. Cell. Proteomics 4:310-327(2005). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-607; SER-706; SER-806;SER-1515; SER-1578; SER-1603; SER-1614 AND SER-2128, AND MASSSPECTROMETRY. | |
