THTR_YEAST - dbPTM
THTR_YEAST - PTM Information in dbPTM
Basic Information of Protein
UniProt ID THTR_YEAST
UniProt AC Q08686
Protein Name Thiosulfate sulfurtransferase TUM1
Gene Name TUM1
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length 304
Subcellular Localization Mitochondrion . Cytoplasm .
Protein Description Required for formation of the 2-thio group of the 5-methoxycarbonylmethyl-2-thiouridine modified base in some tRNAs..
Protein Sequence MPLFDLISPKAFVKLVASEKVHRIVPVDATWYLPSWKLDNKVDFLTKPRIPNSIFFDIDAISDKKSPYPHMFPTKKVFDDAMSNLGVQKDDILVVYDRVGNFSSPRCAWTLGVMGHPKVYLLNNFNQYREFKYPLDSSKVAAFSPYPKSHYESSESFQDKEIVDYEEMFQLVKSGELAKKFNAFDARSLGRFEGTEPEPRSDIPSGHIPGTQPLPYGSLLDPETKTYPEAGEAIHATLEKALKDFHCTLDPSKPTICSCGTGVSGVIIKTALELAGVPNVRLYDGSWTEWVLKSGPEWIAENRD
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
8PhosphorylationMPLFDLISPKAFVKL
CCHHHCCCHHHHHHH		27.8722369663
47AcetylationNKVDFLTKPRIPNSI
CCCCCCCCCCCCCCE		34.1524489116
62PhosphorylationFFDIDAISDKKSPYP
EEEHHHHCCCCCCCC		45.1319779198
64AcetylationDIDAISDKKSPYPHM
EHHHHCCCCCCCCCC		48.6524489116
132AcetylationFNQYREFKYPLDSSK
HHHCCCCCCCCCCCC		41.0024489116
148AcetylationAAFSPYPKSHYESSE
CCCCCCCHHHCCCCC		43.9824489116
188PhosphorylationFNAFDARSLGRFEGT
CCCCCHHHHCCCCCC		36.5828889911
201PhosphorylationGTEPEPRSDIPSGHI
CCCCCCCCCCCCCCC		51.0828889911
264PhosphorylationCSCGTGVSGVIIKTA
CCCCCCCCHHHHHHH		28.7828889911
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of THTR_YEAST !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of THTR_YEAST !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of THTR_YEAST !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
SWI5_YEASTSWI5genetic
20093466
GET2_YEASTGET2genetic
20093466
FRMSR_YEASTYKL069Wgenetic
20093466
NU133_YEASTNUP133genetic
20093466
RS30A_YEASTRPS30Agenetic
20093466
RS30B_YEASTRPS30Agenetic
20093466
ROM2_YEASTROM2genetic
20093466
SCS7_YEASTSCS7genetic
20093466
TPM1_YEASTTPM1genetic
20093466
AIM44_YEASTAIM44genetic
20093466
SWI5_YEASTSWI5genetic
27708008
H2A1_YEASTHTA1genetic
27708008
GET2_YEASTGET2genetic
27708008
GOSR1_YEASTGOS1genetic
27708008
FRMSR_YEASTYKL069Wgenetic
27708008
ROM2_YEASTROM2genetic
27708008
VPS9_YEASTVPS9genetic
27708008
PKR1_YEASTPKR1genetic
27708008
TPM1_YEASTTPM1genetic
27708008
EOS1_YEASTEOS1genetic
27708008
GGPPS_YEASTBTS1genetic
27708008
AIM44_YEASTAIM44genetic
27708008
LST4_YEASTLST4genetic
28810701
LST7_YEASTLST7genetic
28810701
THRSP_HUMANTHRSPphysical
27107014
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of THTR_YEAST

loading...

Related Literatures of Post-Translational Modification
Phosphorylation
ReferencePubMed
"A multidimensional chromatography technology for in-depthphosphoproteome analysis.";
Albuquerque C.P., Smolka M.B., Payne S.H., Bafna V., Eng J., Zhou H.;
Mol. Cell. Proteomics 7:1389-1396(2008).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-264, AND MASSSPECTROMETRY.

TOP
© 2024 Institute of Bioinformatics and Systems Biology, NYCU | Designed by : BiOmics Laboratory