| UniProt ID | TRM9_YEAST | |
|---|---|---|
| UniProt AC | P49957 | |
| Protein Name | tRNA (carboxymethyluridine(34)-5-O)-methyltransferase | |
| Gene Name | TRM9 | |
| Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast). | |
| Sequence Length | 279 | |
| Subcellular Localization | Cytoplasm . Nucleus . | |
| Protein Description | Required for the methylation of the wobble bases at position 34 in tRNA. Appears to have a role in stress-response.. | |
| Protein Sequence | MEINQAAEKEQEYVHKVYNEIAPHFSQTRYKPWPIVTQFLKTRPMGSIGIDVGCGNGKYLGVNPDIYIIGSDRSDGLIECARGINPSYNLLVADGLNLPHKNETFDFAISIAVVHHWSTRERRVEVIRHVLSKLRQGGQALIYCWALEQGSSRRGYHEGMEQDVFVPWVLPKSKSKPKTKSTPPAKVKTRPKPNLMNIPPKERSEYLQRWKEEQQRSKSLDDNDEKQQQDQEQEREEVKYRYYHLYREGELAEDCRQAGAAVHSEGFERDNWWVVAQKR | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 9 | Acetylation | EINQAAEKEQEYVHK CHHHHHHHHHHHHHH | 61.03 | 24489116 | |
| 26 | Phosphorylation | NEIAPHFSQTRYKPW HHHHHCCCCCCCCCC | 27.84 | 30377154 | |
| 47 | Phosphorylation | LKTRPMGSIGIDVGC HHCCCCCEEEEEECC | 16.05 | 27017623 | |
| 67 | Phosphorylation | LGVNPDIYIIGSDRS ECCCCCEEEECCCCC | 8.21 | 27017623 | |
| 71 | Phosphorylation | PDIYIIGSDRSDGLI CCEEEECCCCCCCHH | 21.31 | 27017623 | |
| 217 | Phosphorylation | WKEEQQRSKSLDDND HHHHHHHHHCCCCCH | 23.43 | 24961812 | |
| 219 | Phosphorylation | EEQQRSKSLDDNDEK HHHHHHHCCCCCHHH | 37.97 | 19795423 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of TRM9_YEAST !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of TRM9_YEAST !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of TRM9_YEAST !! | ||||||
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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