| UniProt ID | CSE1_YEAST | |
|---|---|---|
| UniProt AC | P33307 | |
| Protein Name | Importin alpha re-exporter | |
| Gene Name | CSE1 | |
| Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast). | |
| Sequence Length | 960 | |
| Subcellular Localization | Cytoplasm. Nucleus. | |
| Protein Description | Export receptor for importin alpha (SRP1). Mediates importin-alpha re-export from the nucleus to the cytoplasm after import substrates have been released into the nucleoplasm.. | |
| Protein Sequence | MSDLETVAKFLAESVIASTAKTSERNLRQLETQDGFGLTLLHVIASTNLPLSTRLAGALFFKNFIKRKWVDENGNHLLPANNVELIKKEIVPLMISLPNNLQVQIGEAISSIADSDFPDRWPTLLSDLASRLSNDDMVTNKGVLTVAHSIFKRWRPLFRSDELFLEIKLVLDVFTAPFLNLLKTVDEQITANENNKASLNILFDVLLVLIKLYYDFNCQDIPEFFEDNIQVGMGIFHKYLSYSNPLLEDPDETEHASVLIKVKSSIQELVQLYTTRYEDVFGPMINEFIQITWNLLTSISNQPKYDILVSKSLSFLTAVTRIPKYFEIFNNESAMNNITEQIILPNVTLREEDVELFEDDPIEYIRRDLEGSDTDTRRRACTDFLKELKEKNEVLVTNIFLAHMKGFVDQYMSDPSKNWKFKDLYIYLFTALAINGNITNAGVSSTNNLLNVVDFFTKEIAPDLTSNNIPHIILRVDAIKYIYTFRNQLTKAQLIELMPILATFLQTDEYVVYTYAAITIEKILTIRESNTSPAFIFHKEDISNSTEILLKNLIALILKHGSSPEKLAENEFLMRSIFRVLQTSEDSIQPLFPQLLAQFIEIVTIMAKNPSNPRFTHYTFESIGAILNYTQRQNLPLLVDSMMPTFLTVFSEDIQEFIPYVFQIIAFVVEQSATIPESIKPLAQPLLAPNVWELKGNIPAVTRLLKSFIKTDSSIFPDLVPVLGIFQRLIASKAYEVHGFDLLEHIMLLIDMNRLRPYIKQIAVLLLQRLQNSKTERYVKKLTVFFGLISNKLGSDFLIHFIDEVQDGLFQQIWGNFIITTLPTIGNLLDRKIALIGVLNMVINGQFFQSKYPTLISSTMNSIIETASSQSIANLKNDYVDLDNLEEISTFGSHFSKLVSISEKPFDPLPEIDVNNGVRLYVAEALNKYNAISGNTFLNTILPQLTQENQVKLNQLLVGN | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 18 | Phosphorylation | LAESVIASTAKTSER HHHHHHHHCCCCCHH | 20.13 | 28889911 | |
| 19 | Phosphorylation | AESVIASTAKTSERN HHHHHHHCCCCCHHH | 24.13 | 28889911 | |
| 62 | Acetylation | LAGALFFKNFIKRKW HHHHHHHHHHHHHHC | 43.55 | 24489116 | |
| 68 | Acetylation | FKNFIKRKWVDENGN HHHHHHHHCCCCCCC | 46.71 | 24489116 | |
| 87 | Acetylation | ANNVELIKKEIVPLM CCCCHHCHHHHHHHH | 57.91 | 24489116 | |
| 123 | Phosphorylation | DFPDRWPTLLSDLAS CCCCCHHHHHHHHHH | 33.11 | 29688323 | |
| 126 | Phosphorylation | DRWPTLLSDLASRLS CCHHHHHHHHHHHCC | 33.42 | 29688323 | |
| 130 | Phosphorylation | TLLSDLASRLSNDDM HHHHHHHHHCCCCCC | 40.84 | 29688323 | |
| 152 | Acetylation | TVAHSIFKRWRPLFR HHHHHHHHHHHCCCC | 49.75 | 24489116 | |
| 184 | Phosphorylation | PFLNLLKTVDEQITA HHHHHHHHHHHHHHC | 32.91 | 28889911 | |
| 411 | Phosphorylation | MKGFVDQYMSDPSKN HCHHHHHHCCCCCCC | 8.30 | 27017623 | |
| 566 | Acetylation | KHGSSPEKLAENEFL HHCCCHHHHHHCHHH | 57.28 | 24489116 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of CSE1_YEAST !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of CSE1_YEAST !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of CSE1_YEAST !! | ||||||
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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| Phosphorylation | |
| Reference | PubMed |
| "A multidimensional chromatography technology for in-depthphosphoproteome analysis."; Albuquerque C.P., Smolka M.B., Payne S.H., Bafna V., Eng J., Zhou H.; Mol. Cell. Proteomics 7:1389-1396(2008). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-18, AND MASSSPECTROMETRY. | |
