dbPTM

YL054_YEAST - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	YL054_YEAST
UniProt AC	Q12244
Protein Name	Uncharacterized transcriptional regulatory protein YLL054C
Gene Name	YLL054C
Organism	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length	843
Subcellular Localization	Nucleus .
Protein Description	Required for growth on non-fermentable carbon sources..
Protein Sequence	MSIASQKKVKPSFVCLRCKQRKIKCDKLWPTCSKCKASSSICSYEVEPGRINKSPTIENAPHRDIRNITPASMSASGSFTSILNPSTKDWEMKNFAMNLSNAHDKLVVMNNTTIVDSPFAFHSILQHDLYAKALTTCIHERILIDVERHRENVSANNKKRELNLTIGDIGPLFFIDKAALKFIENTSKTSKLYPPIDFLYNTYDYEQAHPEENNDKISINILLEELSKYFLNKNEVDGLIVDFYKTIYPVYPLLEISLFEDNIRELLQLNEFNGYNIVFAGKDSRRKLETITLLTIILAFSYRRLSLSTSHSFKESFGVKSNNLTLLAHKLLALMNVFQYVNEHTLCCLLYFFILRYLNPDQADMYPTHSDILNLKFLENVAIKLGLNEEPFQYTRYVSESDDYPRLFNLRRKLWLGVQFLKFGILIPEGDSDILSLEYLRSFMKTDESLPELFERNYASTNNLDLSLMATAENIYHLHLSLQVLLTSCFPINGPSYLKEVLDNIDKTKDFLNQKFPLILSSLGEPRMKSLHINVPSSLANEESFDFSTFEENETFIANVISYTCTMNIYDSLSLHFENQCFKNALEYKTYYHRFTFTAIQDYLTLLKLISEYFNGSLLHLREPFGFATQKVVRFSIHRLLIFQATLLVRLFYKKDTCDRSSAAMGMLNDRNGRLSRVIEKMIKLMSYHMKLLVEIVISKLEKSYLGSFISVSIFRYIIYLVDTDALSAFISDYWKSDAVMDERYSRIHRIVGLKWGMGRDKSFSFTSKLNNPQFLGSLDLEILEELEKLISAQEFSRNFTEDVDESLQSEIDLMNYDNEALNQLMAIDLDKLLGIFPNLSNF

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
5	Phosphorylation	---MSIASQKKVKPS ---CCCCCCCCCCCC	40.64	30377154
54	Phosphorylation	EPGRINKSPTIENAP CCCCCCCCCCCCCCC	23.84	25704821
56	Phosphorylation	GRINKSPTIENAPHR CCCCCCCCCCCCCCC	48.27	17330950

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of YL054_YEAST !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of YL054_YEAST !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of YL054_YEAST !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
ECM33_YEAST	ECM33	genetic	20093466
MPC2_YEAST	MPC2	genetic	20093466
YJ9J_YEAST	YJR142W	genetic	20093466
TPM1_YEAST	TPM1	genetic	20093466
SGT2_YEAST	SGT2	genetic	20093466
SRO7_YEAST	SRO7	genetic	20093466
PPAL_YEAST	LTP1	genetic	20093466
YP096_YEAST	YPR096C	genetic	20093466
CGS5_YEAST	CLB5	genetic	20093466
BLM10_YEAST	BLM10	genetic	27708008
IES1_YEAST	IES1	genetic	27708008
ATG8_YEAST	ATG8	genetic	27708008
ECM33_YEAST	ECM33	genetic	27708008
SNF1_YEAST	SNF1	genetic	27708008
MIG1_YEAST	MIG1	genetic	27708008
ITC1_YEAST	ITC1	genetic	27708008
FKS2_YEAST	GSC2	genetic	27708008
ASK10_YEAST	ASK10	genetic	27708008
SYF2_YEAST	SYF2	genetic	27708008
YG3O_YEAST	YGR153W	genetic	27708008
TBP7_YEAST	YTA7	genetic	27708008
YJ9J_YEAST	YJR142W	genetic	27708008
UPS1_YEAST	UPS1	genetic	27708008
NU188_YEAST	NUP188	genetic	27708008
LSM7_YEAST	LSM7	genetic	27708008
MSH2_YEAST	MSH2	genetic	27708008
OST3_YEAST	OST3	genetic	27708008
YME1_YEAST	YME1	genetic	27708008
THP3_YEAST	THP3	genetic	27708008
YP096_YEAST	YPR096C	genetic	27708008
MMS1_YEAST	MMS1	genetic	27708008

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of YL054_YEAST

Related Literatures of Post-Translational Modification

Phosphorylation
Reference	PubMed
"A multidimensional chromatography technology for in-depthphosphoproteome analysis."; Albuquerque C.P., Smolka M.B., Payne S.H., Bafna V., Eng J., Zhou H.; Mol. Cell. Proteomics 7:1389-1396(2008). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT THR-56, AND MASSSPECTROMETRY.	18407956 [Abstract]