dbPTM

LDS2_YEAST - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	LDS2_YEAST
UniProt AC	Q08218
Protein Name	Outer spore wall protein LDS2 {ECO:0000305\|PubMed:23966878}
Gene Name	LDS2 {ECO:0000303\|PubMed:23966878}
Organism	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length	356
Subcellular Localization	Prospore membrane Multi-pass membrane protein . Lipid droplet . Spore wall . Localizes to the ascal side of growing prospore membranes in mid-meiosis II and to the spore wall in post-meiotic cells. Localizes to a specific subset of lipid droplets a
Protein Description	Involved in spore wall assembly..
Protein Sequence	MSTRPQPDWYYHRHPYASTPLAEGEEPQLLPIQDQGNHKKSKIWMAYKAPIVRWYKNAMLVKDNFWKDLESSHQIIWYPYKGISESVGNSDYLHLFFLIFGYYLLNLLLIVAFTSILAWSLLVCIYLPFLGLFALPLAYMQTILISTTLCNSMVKGTDFVLFTRIYGVTFARKGLTELSEACETISFTPFVYRRSHRLGGLFSKRFYLVSLPQFFIFFFWYIFIAFMFLLLLLVPIVGPITINMLPFSPGMGFYYFEPYFVDVLHLDSRKLSKVYYKGFAKWLLYSISSGLLESIPILGGLFIGTNAVGASLWIVKEIKDRDQPAVPPSPPAEPEEPTVGSYAPPIQQSIAHINPP

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	Reference
10	Phosphorylation	TRPQPDWYYHRHPYA CCCCCCCCCCCCCCC	29650682
11	Phosphorylation	RPQPDWYYHRHPYAS CCCCCCCCCCCCCCC	29650682
329	Phosphorylation	DQPAVPPSPPAEPEE CCCCCCCCCCCCCCC	27214570

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of LDS2_YEAST !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of LDS2_YEAST !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of LDS2_YEAST !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
SSB1_YEAST	SSB1	physical	22940862
MAL12_YEAST	MAL12	genetic	27708008
RL6B_YEAST	RPL6B	genetic	27708008
ALG14_YEAST	ALG14	genetic	27708008
SYG_YEAST	GRS1	genetic	27708008
DPOD_YEAST	POL3	genetic	27708008
KIN28_YEAST	KIN28	genetic	27708008
FAL1_YEAST	FAL1	genetic	27708008
SLU7_YEAST	SLU7	genetic	27708008
CDC1_YEAST	CDC1	genetic	27708008
UTP5_YEAST	UTP5	genetic	27708008
MOB2_YEAST	MOB2	genetic	27708008
ACT_YEAST	ACT1	genetic	27708008
STT3_YEAST	STT3	genetic	27708008
MCE1_YEAST	CEG1	genetic	27708008
IPI1_YEAST	IPI1	genetic	27708008
PRI1_YEAST	PRI1	genetic	27708008
ARP4_YEAST	ARP4	genetic	27708008
TIM16_YEAST	PAM16	genetic	27708008
CDC11_YEAST	CDC11	genetic	27708008
MIF2_YEAST	MIF2	genetic	27708008
RSC4_YEAST	RSC4	genetic	27708008
POB3_YEAST	POB3	genetic	27708008
ERB1_YEAST	ERB1	genetic	27708008
SEC63_YEAST	SEC63	genetic	27708008
CET1_YEAST	CET1	genetic	27708008
PP2C3_YEAST	PTC3	genetic	27708008
YGZ2_YEAST	YGL242C	genetic	27708008
ADH4_YEAST	ADH4	genetic	27708008
RME1_YEAST	RME1	genetic	27708008
IGO2_YEAST	IGO2	genetic	27708008
AIM18_YEAST	AIM18	genetic	27708008
CPT1_YEAST	CPT1	genetic	27708008
LDS1_YEAST	LDS1	genetic	27216456
RRT8_YEAST	RRT8	genetic	27216456
SEC39_YEAST	SEC39	physical	27216456

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of LDS2_YEAST

Related Literatures of Post-Translational Modification