MRN1_YEAST - dbPTM
MRN1_YEAST - PTM Information in dbPTM
Basic Information of Protein
UniProt ID MRN1_YEAST
UniProt AC Q08925
Protein Name RNA-binding protein MRN1
Gene Name MRN1
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length 612
Subcellular Localization Cytoplasm .
Protein Description RNA-binding protein that binds specific categories of mRNAs, including those that contain upstream open reading frames (uORFs) and internal ribosome entry sites (IRES). Probably involved in translational regulation..
Protein Sequence MVVSYNNNNNNNNNNNNNNISNNNNNNNMFPPFPSSDDFAMYQQSSSSGPYQETYASGPQNFGDAVYPMNGNFTLLPSDFTREPNDSFFYENDGIFDYQRIQQQPTQFQTKQRNDSQQQRFSQEQNFEIDNEVVHNNNRYYEYERSSNEVSPFDDENPNVLSDGMSPTIMATATAVTNANAPLPVNAQANNPLNFTSAPSRTVYLGNVPPNLSVKELLDHVRSGVVEDVKIIPEKMCAFVSFIDESAALLFHSDAILKRLNIGDRDIKIGWGKPTRIDPIVAARISTDGATRNVYIGRMTIEGEESHLSEEQLRVDLEEYGEIDCIKIIKEKGIAFIHFASILNAIKVVTNLPIRNPYYQNKRIFYGKDRCAFITKTQQHNAAQFLGVQPGMEHMIEFSDREFISNALLQQSAAAAAIATSAGGPNNLGNRTVYLGSLPKDVKIEEICNAVRGGLLQSIKLLNDRYVCFVTFIDPTAAAQFYAMSSLYGFTVQKKRCKVGWGKHSGPLPNALALAVSNGASRNVYVGNIDFVGDSLRDERVFTESNLRHIFQQYGEVEQINFLPEKNCCFINYTNISNAILALDKIKSNPYFKDLKINFGKDRCGNVPHQSR
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
87PhosphorylationFTREPNDSFFYENDG
CCCCCCCCCEECCCC		24.7230377154
111UbiquitinationQPTQFQTKQRNDSQQ
CCCCCCCCCCCHHHH		36.1623749301
116PhosphorylationQTKQRNDSQQQRFSQ
CCCCCCHHHHHHHHH		33.1827214570
122PhosphorylationDSQQQRFSQEQNFEI
HHHHHHHHHHHCEEE		34.6928889911
437PhosphorylationNRTVYLGSLPKDVKI
CCEEEECCCCCCCCH		38.6128889911
440AcetylationVYLGSLPKDVKIEEI
EEECCCCCCCCHHHH		79.1724489116
460AcetylationGGLLQSIKLLNDRYV
CCHHHHHHHHCCCEE		52.7724489116
503AcetylationRCKVGWGKHSGPLPN
CCCCCCCCCCCCCCC		28.2624489116
543PhosphorylationLRDERVFTESNLRHI
CCCCCCCCHHHHHHH		35.3327214570
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of MRN1_YEAST !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of MRN1_YEAST !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of MRN1_YEAST !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
YBB0_YEASTYBL010Cgenetic
27708008
BDF2_YEASTBDF2genetic
27708008
UGA3_YEASTUGA3genetic
27708008
ATIF_YEASTINH1genetic
27708008
MNN10_YEASTMNN10genetic
27708008
EXG2_YEASTEXG2genetic
27708008
SUR2_YEASTSUR2genetic
27708008
YFT2_YEASTYFT2genetic
27708008
YGD9_YEASTYGL039Wgenetic
27708008
YGS6_YEASTYGL176Cgenetic
27708008
RTF1_YEASTRTF1genetic
27708008
MTL1_YEASTMTL1genetic
27708008
TIM21_YEASTTIM21genetic
27708008
YIA6_YEASTYIA6genetic
27708008
SHE2_YEASTSHE2genetic
27708008
EIF3J_YEASTHCR1genetic
27708008
HRD3_YEASTHRD3genetic
27708008
VAC14_YEASTVAC14genetic
27708008
DUS4_YEASTDUS4genetic
27708008
CSI1_YEASTCSI1genetic
27708008
SHH3_YEASTSHH3genetic
27708008
UBP8_YEASTUBP8genetic
27708008
YO024_YEASTYOL024Wgenetic
27708008
NGL1_YEASTNGL1genetic
27708008
TRM11_YEASTTRM11genetic
27708008
HSP73_YEASTSSA3genetic
27708008
GID4_YEASTVID24genetic
27708008
YBY8_YEASTYBR138Cgenetic
27708008
SDHF4_YEASTSDH8genetic
27708008
BUD3_YEASTBUD3genetic
27708008
RMD1_YEASTRMD1genetic
27708008
MTU1_YEASTSLM3genetic
27708008
PRM7_YEASTPRM7genetic
27708008
PEX19_YEASTPEX19genetic
27708008
TPS2_YEASTTPS2genetic
27708008
DPB4_YEASTDPB4genetic
27708008
SWF1_YEASTSWF1genetic
27708008
SWI5_YEASTSWI5genetic
27708008
TRM82_YEASTTRM82genetic
27708008
MTH1_YEASTMTH1genetic
27708008
INM2_YEASTINM2genetic
27708008
RT103_YEASTRTT103genetic
27708008
SWR1_YEASTSWR1genetic
27708008
SIP1_YEASTSIP1genetic
27708008
PP2C2_YEASTPTC2genetic
27708008
AST2_YEASTAST2genetic
27708008
PMD1_YEASTPMD1genetic
27708008
UBP5_YEASTUBP5genetic
27708008
EMP47_YEASTEMP47genetic
27708008
SLX9_YEASTSLX9genetic
27708008
PIH1_YEASTPIH1genetic
27708008
VTC4_YEASTVTC4genetic
27708008
SIP4_YEASTSIP4genetic
27708008
MOG1_YEASTMOG1genetic
27708008
TCTP_YEASTTMA19genetic
27708008
BLI1_YEASTBLI1genetic
27708008
YKH5_YEASTYKL075Cgenetic
27708008
SA190_YEASTSAP190genetic
27708008
MLH2_YEASTMLH2genetic
27708008
SRL2_YEASTSRL2genetic
27708008
RAX2_YEASTRAX2genetic
27708008
RKM5_YEASTRKM5genetic
27708008
SHH4_YEASTSHH4genetic
27708008
VPS71_YEASTVPS71genetic
27708008
YMF3_YEASTYML053Cgenetic
27708008
CIN4_YEASTCIN4genetic
27708008
SSO2_YEASTSSO2genetic
27708008
GCSP_YEASTGCV2genetic
27708008
FAR11_YEASTFAR11genetic
27708008
LSM7_YEASTLSM7genetic
27708008
MDM12_YEASTMDM12genetic
27708008
HMI1_YEASTHMI1genetic
27708008
SKM1_YEASTSKM1genetic
27708008
ERP4_YEASTERP4genetic
27708008
LIPA_YEASTLIP5genetic
27708008
MCP1_YEASTMCP1genetic
27708008
RAD1_YEASTRAD1genetic
27708008
TRM44_YEASTTRM44genetic
27708008
NACB1_YEASTEGD1genetic
27708008
MDM36_YEASTMDM36genetic
27708008
AXL1_YEASTAXL1genetic
27708008
PMP1_YEASTPMP1physical
26404137
RL36A_YEASTRPL36Agenetic
29158977
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of MRN1_YEAST

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Related Literatures of Post-Translational Modification
Phosphorylation
ReferencePubMed
"A multidimensional chromatography technology for in-depthphosphoproteome analysis.";
Albuquerque C.P., Smolka M.B., Payne S.H., Bafna V., Eng J., Zhou H.;
Mol. Cell. Proteomics 7:1389-1396(2008).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-437, AND MASSSPECTROMETRY.

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