dbPTM

NGL1_YEAST - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	NGL1_YEAST
UniProt AC	Q08213
Protein Name	RNA exonuclease NGL1
Gene Name	NGL1
Organism	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length	363
Subcellular Localization
Protein Description
Protein Sequence	MFTRRFIPVVQSTKQNIGKYVRKDARFTLLTYNMLSPSYMWPQVYTYVAEPYKNWSYRHRLLEKELLNTFKADIMCLQEMTARDYEDYWHDSIGVDVNYGSKFISKTPPKYWKKPVKDMDGVSIFYNLAKFDFISSSGIYLNQLLNVFNQRELKYLYNKKVTLTDGASNVIGEDSLLDVLKGKNQVCLFVSLRHKETGTIFVVLNTHLYWKYDEVKLTQCMIIMRELSKIIKQLLPGDVKGQERVKILFTGDLNSTRDSLVVNFLQGQIVSHGDLNLINPMRPYLDRCVYDDIPKDYFVHTCYSGKLKGIFDYVWYHDSDFLLTKILTGNEVSDELLASNQLGLPNENHPSDHIPLLTEFKIL

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
64	Acetylation	YRHRLLEKELLNTFK HHHHHHHHHHHHHHH	54.34	24489116
88	Phosphorylation	TARDYEDYWHDSIGV HHCCHHHHCCCCEEE	7.84	27017623
92	Phosphorylation	YEDYWHDSIGVDVNY HHHHCCCCEEECCCC	14.35	27017623
99	Phosphorylation	SIGVDVNYGSKFISK CEEECCCCCCCCCCC	23.71	27017623

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of NGL1_YEAST !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of NGL1_YEAST !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of NGL1_YEAST !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
ATG15_YEAST	ATG15	genetic	27708008
ILM1_YEAST	ILM1	genetic	27708008
SST2_YEAST	SST2	genetic	27708008
STB4_YEAST	STB4	genetic	27708008
DMA2_YEAST	DMA2	genetic	27708008
PYC2_YEAST	PYC2	genetic	27708008
QRI7_YEAST	QRI7	genetic	27708008
S2538_YEAST	YDL119C	genetic	27708008
VPS41_YEAST	VPS41	genetic	27708008
H2A1_YEAST	HTA1	genetic	27708008
XRS2_YEAST	XRS2	genetic	27708008
SHE9_YEAST	SHE9	genetic	27708008
RAD4_YEAST	RAD4	genetic	27708008
MMS2_YEAST	MMS2	genetic	27708008
VAM7_YEAST	VAM7	genetic	27708008
ADH4_YEAST	ADH4	genetic	27708008
PHB2_YEAST	PHB2	genetic	27708008
RS27B_YEAST	RPS27B	genetic	27708008
MED20_YEAST	SRB2	genetic	27708008
AIM18_YEAST	AIM18	genetic	27708008
FLX1_YEAST	FLX1	genetic	27708008
THIK_YEAST	POT1	genetic	27708008
YJY1_YEAST	YJR011C	genetic	27708008
CBF1_YEAST	CBF1	genetic	27708008
DHOM_YEAST	HOM6	genetic	27708008
IXR1_YEAST	IXR1	genetic	27708008
AIM26_YEAST	AIM26	genetic	27708008
VPS24_YEAST	VPS24	genetic	27708008
YKE44_YEAST	YKL044W	genetic	27708008
MDM35_YEAST	MDM35	genetic	27708008
DCOR_YEAST	SPE1	genetic	27708008
SAC1_YEAST	SAC1	genetic	27708008
YRA2_YEAST	YRA2	genetic	27708008
CTH2_YEAST	TIS11	genetic	27708008
MMR1_YEAST	MMR1	genetic	27708008
COQ11_YEAST	YLR290C	genetic	27708008
YPT7_YEAST	YPT7	genetic	27708008
UBX2_YEAST	UBX2	genetic	27708008
TSA1_YEAST	TSA1	genetic	27708008
RAD52_YEAST	RAD52	genetic	27708008
PML39_YEAST	PML39	genetic	27708008
TDA1_YEAST	TDA1	genetic	27708008
GAS1_YEAST	GAS1	genetic	27708008
PET8_YEAST	PET8	genetic	27708008
NIS1_YEAST	NIS1	genetic	27708008
KC12_YEAST	YCK2	genetic	27708008
ALDH6_YEAST	ALD6	genetic	27708008
GGPPS_YEAST	BTS1	genetic	27708008
SRO7_YEAST	SRO7	genetic	27708008

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of NGL1_YEAST

Related Literatures of Post-Translational Modification