TCTP_YEAST - dbPTM
TCTP_YEAST - PTM Information in dbPTM
Basic Information of Protein
UniProt ID TCTP_YEAST
UniProt AC P35691
Protein Name Translationally-controlled tumor protein homolog
Gene Name TMA19
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length 167
Subcellular Localization Cytoplasm, cytoskeleton. Mitochondrion. After induction of apoptosis or mild oxidative stress, reversibly translocates from the cytoplasm to mitochondria, where it is associated with the outer surface.
Protein Description Involved in protein synthesis. Involved in microtubule stabilization..
Protein Sequence MIIYKDIFSNDELLSDAYDAKLVDDVIYEADCAMVNVGGDNIDIGANPSAEGGDDDVEEGAEMVNNVVHSFRLQQTAFDKKSFLTYIKGYMKAVKAKLQETNPEEVPKFEKGAQTYVKKVIGSFKDWEFFTGESMDPDAMVVMLNYREDGTTPFVAIWKHGIVEEKI
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
5Ubiquitination---MIIYKDIFSNDE
---CCCCCCCCCCCH		33.6623749301
9PhosphorylationIIYKDIFSNDELLSD
CCCCCCCCCCHHHCH		43.6428889911
15PhosphorylationFSNDELLSDAYDAKL
CCCCHHHCHHCCCCC		32.5922369663
80SuccinylationLQQTAFDKKSFLTYI
CCCCCCCHHHHHHHH		43.8123954790
802-HydroxyisobutyrylationLQQTAFDKKSFLTYI
CCCCCCCHHHHHHHH		43.81-
80AcetylationLQQTAFDKKSFLTYI
CCCCCCCHHHHHHHH		43.8124489116
80UbiquitinationLQQTAFDKKSFLTYI
CCCCCCCHHHHHHHH		43.8123749301
81AcetylationQQTAFDKKSFLTYIK
CCCCCCHHHHHHHHH		48.5724489116
81UbiquitinationQQTAFDKKSFLTYIK
CCCCCCHHHHHHHHH		48.5722817900
82PhosphorylationQTAFDKKSFLTYIKG
CCCCCHHHHHHHHHH		31.0921440633
85PhosphorylationFDKKSFLTYIKGYMK
CCHHHHHHHHHHHHH		22.6121440633
86PhosphorylationDKKSFLTYIKGYMKA
CHHHHHHHHHHHHHH		11.6321440633
88AcetylationKSFLTYIKGYMKAVK
HHHHHHHHHHHHHHH		33.3124489116
92AcetylationTYIKGYMKAVKAKLQ
HHHHHHHHHHHHHHH		41.3624489116
92UbiquitinationTYIKGYMKAVKAKLQ
HHHHHHHHHHHHHHH		41.3623749301
97UbiquitinationYMKAVKAKLQETNPE
HHHHHHHHHHHCCHH		45.0123749301
972-HydroxyisobutyrylationYMKAVKAKLQETNPE
HHHHHHHHHHHCCHH		45.01-
97AcetylationYMKAVKAKLQETNPE
HHHHHHHHHHHCCHH		45.0124489116
101PhosphorylationVKAKLQETNPEEVPK
HHHHHHHCCHHHCCC		43.0128889911
108SuccinylationTNPEEVPKFEKGAQT
CCHHHCCCHHHHCHH		71.9223954790
108AcetylationTNPEEVPKFEKGAQT
CCHHHCCCHHHHCHH		71.9224489116
108UbiquitinationTNPEEVPKFEKGAQT
CCHHHCCCHHHHCHH		71.9223749301
111AcetylationEEVPKFEKGAQTYVK
HHCCCHHHHCHHHHH		63.7824489116
115PhosphorylationKFEKGAQTYVKKVIG
CHHHHCHHHHHHHHH		29.7323749301
118AcetylationKGAQTYVKKVIGSFK
HHCHHHHHHHHHCCC		30.8024489116
118SuccinylationKGAQTYVKKVIGSFK
HHCHHHHHHHHHCCC		30.8023954790
1192-HydroxyisobutyrylationGAQTYVKKVIGSFKD
HCHHHHHHHHHCCCC		29.10-
123PhosphorylationYVKKVIGSFKDWEFF
HHHHHHHCCCCCEEC		20.2821440633
159SuccinylationTPFVAIWKHGIVEEK
CCEEEEECCCCCCCC		26.3223954790
159UbiquitinationTPFVAIWKHGIVEEK
CCEEEEECCCCCCCC		26.3224961812
166AcetylationKHGIVEEKI------
CCCCCCCCC------		39.9624489116
166UbiquitinationKHGIVEEKI------
CCCCCCCCC------		39.9623749301
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of TCTP_YEAST !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of TCTP_YEAST !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of TCTP_YEAST !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
EF1G2_YEASTTEF4physical
16554755
EF1G1_YEASTCAM1physical
16554755
YBQ6_YEASTYBR056Wgenetic
20093466
DCC1_YEASTDCC1genetic
20093466
FUB1_YEASTFUB1genetic
20093466
H2A1_YEASTHTA1genetic
20093466
PUS3_YEASTDEG1genetic
20093466
RL9A_YEASTRPL9Agenetic
20093466
ASK10_YEASTASK10genetic
20093466
YJ66_YEASTYJR096Wgenetic
20093466
PXL1_YEASTPXL1genetic
20093466
LDB18_YEASTLDB18genetic
20093466
ALAM_YEASTALT1genetic
20093466
PFD6_YEASTYKE2genetic
20093466
FKS1_YEASTFKS1genetic
20093466
TBA3_YEASTTUB3genetic
20093466
YMK8_YEASTYML108Wgenetic
20093466
RL36A_YEASTRPL36Agenetic
20093466
CIK1_YEASTCIK1genetic
20093466
JNM1_YEASTJNM1genetic
20093466
URK1_YEASTURK1genetic
20093466
BRE5_YEASTBRE5genetic
20093466
HSP7F_YEASTSSE1genetic
20093466
MLC2_YEASTMLC2genetic
20093466
AQY1_YEASTAQY1genetic
20093466
SIR2_YEASTSIR2genetic
21902802
CUE5_YEASTCUE5physical
25042851
MED6_YEASTMED6genetic
27708008
SEC65_YEASTSEC65genetic
27708008
YCU0_YEASTYCR050Cgenetic
27708008
YCV1_YEASTYCR061Wgenetic
27708008
ASK10_YEASTASK10genetic
27708008
CDC24_YEASTCDC24genetic
27708008
STU1_YEASTSTU1genetic
27708008
PRP11_YEASTPRP11genetic
27708008
UBC9_YEASTUBC9genetic
27708008
SUB2_YEASTSUB2genetic
27708008
ERF3_YEASTSUP35genetic
27708008
SYF1_YEASTSYF1genetic
27708008
PSB3_YEASTPUP3genetic
27708008
STT3_YEASTSTT3genetic
27708008
CDC20_YEASTCDC20genetic
27708008
GPI10_YEASTGPI10genetic
27708008
CBF3A_YEASTCBF2genetic
27708008
SHQ1_YEASTSHQ1genetic
27708008
MTR4_YEASTMTR4genetic
27708008
SMC3_YEASTSMC3genetic
27708008
PRP21_YEASTPRP21genetic
27708008
PRP19_YEASTPRP19genetic
27708008
CLF1_YEASTCLF1genetic
27708008
SEC22_YEASTSEC22genetic
27708008
GSP1_YEASTGSP1genetic
27708008
MCM1_YEASTMCM1genetic
27708008
DPOA_YEASTPOL1genetic
27708008
PRP2_YEASTPRP2genetic
27708008
RPB2_YEASTRPB2genetic
27708008
RRS1_YEASTRRS1genetic
27708008
ULP1_YEASTULP1genetic
27708008
SEC62_YEASTSEC62genetic
27708008
PRP4_YEASTPRP4genetic
27708008
RL4A_YEASTRPL4Agenetic
27708008
YBQ6_YEASTYBR056Wgenetic
27708008
FUB1_YEASTFUB1genetic
27708008
H2A1_YEASTHTA1genetic
27708008
CAJ1_YEASTCAJ1genetic
27708008
RL9A_YEASTRPL9Agenetic
27708008
PFD3_YEASTPAC10genetic
27708008
CSN12_YEASTYJR084Wgenetic
27708008
YJ66_YEASTYJR096Wgenetic
27708008
RL40A_YEASTRPL40Bgenetic
27708008
RL40B_YEASTRPL40Bgenetic
27708008
FRE8_YEASTFRE8genetic
27708008
SIC1_YEASTSIC1genetic
27708008
PFD6_YEASTYKE2genetic
27708008
UBX2_YEASTUBX2genetic
27708008
YMK8_YEASTYML108Wgenetic
27708008
TBA3_YEASTTUB3genetic
27708008
CTF18_YEASTCTF18genetic
27708008
RL36A_YEASTRPL36Agenetic
27708008
PFD4_YEASTGIM3genetic
27708008
ASE1_YEASTASE1genetic
27708008
FSH3_YEASTFSH3genetic
27708008
HSP7F_YEASTSSE1genetic
27708008
RU2A_YEASTLEA1genetic
27708008
YP078_YEASTYPR078Cgenetic
27708008
MLC2_YEASTMLC2genetic
27708008
AQY1_YEASTAQY1genetic
27708008
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of TCTP_YEAST

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Related Literatures of Post-Translational Modification

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