| UniProt ID | UBC9_YEAST | |
|---|---|---|
| UniProt AC | P50623 | |
| Protein Name | SUMO-conjugating enzyme UBC9 | |
| Gene Name | UBC9 | |
| Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast). | |
| Sequence Length | 157 | |
| Subcellular Localization | Nucleus . | |
| Protein Description | E2 ubiquitin-like--protein ligase mediating SUMO/Smt3 attachment to septins and PCNA. Seems to be involved in degradation of S- (CLB5) and M-phase cyclins (CLB2).. | |
| Protein Sequence | MSSLCLQRLQEERKKWRKDHPFGFYAKPVKKADGSMDLQKWEAGIPGKEGTNWAGGVYPITVEYPNEYPSKPPKVKFPAGFYHPNVYPSGTICLSILNEDQDWRPAITLKQIVLGVQDLLDSPNPNSPAQEPAWRSFSRNKAEYDKKVLLQAKQYSK | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 2 | Acetylation | ------MSSLCLQRL ------CCHHHHHHH | 31.83 | 22814378 | |
| 27 | Acetylation | HPFGFYAKPVKKADG CCCCEECEEEEECCC | 38.68 | 24489116 | |
| 40 | Acetylation | DGSMDLQKWEAGIPG CCCCCHHHHHCCCCC | 55.06 | 24489116 | |
| 122 | Phosphorylation | GVQDLLDSPNPNSPA CHHHHHCCCCCCCCC | 26.92 | 24961812 | |
| 127 | Phosphorylation | LDSPNPNSPAQEPAW HCCCCCCCCCCCCHH | 23.91 | 24961812 | |
| 136 | Phosphorylation | AQEPAWRSFSRNKAE CCCCHHHHHCCCHHH | 19.51 | 24961812 | |
| 138 | Phosphorylation | EPAWRSFSRNKAEYD CCHHHHHCCCHHHHH | 35.87 | 24961812 | |
| 153 | Sumoylation | KKVLLQAKQYSK--- HHHHHHHHHHCC--- | 36.49 | - | |
| 157 | Sumoylation | LQAKQYSK------- HHHHHHCC------- | 60.47 | - |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of UBC9_YEAST !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of UBC9_YEAST !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of UBC9_YEAST !! | ||||||
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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