YH11B_YEAST - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: YH11B_YEAST
• UniProt AC: O13535
• Protein Name: Transposon Ty1-H Gag-Pol polyprotein
• Gene Name: TY1B-H
• Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
• Sequence Length: 1793
• Subcellular Localization: Cytoplasm. Nucleus.
• Protein Description: Capsid protein (CA) is the structural component of the virus-like particle (VLP), forming the shell that encapsulates the retrotransposons dimeric RNA genome. The particles are assembled from trimer-clustered units and there are holes in the capsid shells that allow for the diffusion of macromolecules. CA has also nucleocapsid-like chaperone activity, promoting primer tRNA(i)-Met annealing to the multipartite primer-binding site (PBS), dimerization of Ty1 RNA and initiation of reverse transcription (By similarity).; The aspartyl protease (PR) mediates the proteolytic cleavages of the Gag and Gag-Pol polyproteins after assembly of the VLP.; Reverse transcriptase/ribonuclease H (RT) is a multifunctional enzyme that catalyzes the conversion of the retro-elements RNA genome into dsDNA within the VLP. The enzyme displays a DNA polymerase activity that can copy either DNA or RNA templates, and a ribonuclease H (RNase H) activity that cleaves the RNA strand of RNA-DNA heteroduplexes during plus-strand synthesis and hydrolyzes RNA primers. The conversion leads to a linear dsDNA copy of the retrotransposon that includes long terminal repeats (LTRs) at both ends (By similarity).; Integrase (IN) targets the VLP to the nucleus, where a subparticle preintegration complex (PIC) containing at least integrase and the newly synthesized dsDNA copy of the retrotransposon must transit the nuclear membrane. Once in the nucleus, integrase performs the integration of the dsDNA into the host genome (By similarity)..
• Protein Sequence: MESQQLSNYPHISHGSACASVTSKEVHTNQDPLDVSASKIQEYDKASTKANSQQTTTPASSAVPENLHHASPQPASVPPPQNGPYPQQCMMTQNQANPSGWSFYGHPSMIPYTPYQMSPMYFPPGPQSQFPQYPSSVGTPLSTPSPESGNTFTDSSSADSDMTSTKKYVRPPPMLTSPNDFPNWVKTYIKFLQNSNLGGIIPTVNGKPVPPMLTSPNDFPNWVKTYIKFLQNSNLGGIIPTVNGKPVRQITDDELTFLYNTFQIFAPSQFLPTWVKDILSVDYTDIMKILSKSIEKMQSDTQEANDIVTLANLQYNGSTPADAFETKVTNIIDRLNNNGIHINNKVACQLIMRGLSGEYKFLRYTRHRHLNMTVAELFLDIHAIYEEQQGSRNSKPNYRRNPSDEKNDSRSYTNTTKPKVIARNPQKTNNSKSKTARAHNVSTSNNSPSTDNDSISKSTTEPIQLNNKHDLHLGQKLTESTVNHTNHSDDELPGHLLLDSGASRTLIRSAHHIHSASSNPDINVVDAQKRNIPINAIGDLQFHFQDNTKTSIKVLHTPNIAYDLLSLNELAAVDITACFTKNVLERSDGTVLAPIVKYGDFYWVSKKYLLPSNISVPTINNVHTSESTRKYPYPFIHRMLAHANAQTIRYSLKNNTITYFNESDVDWSSAIDYQCPDCLIGKSTKHRHIKGSRLKYQNSYEPFQYLHTDIFGPVHNLPKSAPSYFISFTDETTKFRWVYPLHDRREDSILDVFTTILAFIKNQFQASVLVIQMDRGSEYTNRTLHKFLEKNGITPCYTTTADSRAHGVAERLNRTLLDDCRTQLQCSGLPNHLWFSAIEFSTIVRNSLASPKSKKSARQHAGLAGLDISTLLPFGQPVIVNDHNPNSKIHPRGIPGYALHPSRNSYGYIIYLPSLKKTVDTTNYVILQGKESRLDQFNYDALTFDEDLNRLTASYHSFIASNEIQQSNDLNIESDHDFQSDIELHPEQLRNVLSKAVSPTDSTPPSTHTEDSKRVSKTNIRAPREVDPNISESNILPSKKRSSTPQISDIESTGSGGMHRLDVPLLAPMSQSNTHESSHASKSKDFRHSDSYSDNETNHTNVPISSTGGTNNKTVPQTSEQETEKRIIHRSPSIDTSSSESNSLHHVVPIKTSDTCPKENTEESIIADLPLPDLPPEPPTELSDSFKELPPINSHQTNSSLGGIGDSNAYTTINSKKRSLEDNETEIKVSRDTWNTKNMRSLEPPRSKKRIHLIAAVKAVKSIKPIRTTLRYDEAITYNKDIKEKEKYIQAYHKEVNQLLMMKTWDTDRYYDRKEIDPKRVINSMFIFNRKRDGTHKARFVARGDIQHPDTYDPGMQSNTVHHYALMTSLSLALDNNYYITQLDISSAYLYADIKEELYIRPPPHLGMNDKLIRLKKSLYGLKQSGANWYETIKSYLIKQCGMEEVRGWSCVFKNSQVTICLFVDDMILFSKDLNANKKIITTLKKQYDTKIINLGESDNEIQYDILGLEIKYQRGKYMKLGMENSLTEKIPKLNVPLNPKGRKLSAPGQPGLYIDQDELEIDEDEYKEKVHEMQKLIGLASYVGYKFRFDLLYYINTLAQHILFPSRQVLDMTYELIQFMWDTRDKQLIWHKNKPTEPDNKLVAISDASYGNQPYYKSQIGNIYLLNGKVIGGKSTKASLTCTSTTEAEIHAISESVPLLNNLSHLVQELNKKPITKGLLTDSKSTISIIISNNEEKFRNRFFGTKAMRLRDEVSGNHLHVCYIETKKNIADVMTKPLPIKTFKLLTNKWIH

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
1	Acetylation	-------MESQQLSN -------CCCCCCCC	46.79	-
13	Phosphorylation	LSNYPHISHGSACAS CCCCCCCCCCCCCCC	20.82	15665377
16	Phosphorylation	YPHISHGSACASVTS CCCCCCCCCCCCCCC	18.10	28889911
20	Phosphorylation	SHGSACASVTSKEVH CCCCCCCCCCCCCCC	26.30	28889911
22	Phosphorylation	GSACASVTSKEVHTN CCCCCCCCCCCCCCC	31.42	28889911
23	Phosphorylation	SACASVTSKEVHTNQ CCCCCCCCCCCCCCC	25.35	19823750
24	Ubiquitination	ACASVTSKEVHTNQD CCCCCCCCCCCCCCC	55.16	17644757
28	Phosphorylation	VTSKEVHTNQDPLDV CCCCCCCCCCCCCCC	39.49	28889911
36	Phosphorylation	NQDPLDVSASKIQEY CCCCCCCCHHHHHHH	26.88	25521595
38	Phosphorylation	DPLDVSASKIQEYDK CCCCCCHHHHHHHHH	23.84	25521595
39	Acetylation	PLDVSASKIQEYDKA CCCCCHHHHHHHHHH	48.39	24489116
39	Ubiquitination	PLDVSASKIQEYDKA CCCCCHHHHHHHHHH	48.39	24961812
43	Phosphorylation	SASKIQEYDKASTKA CHHHHHHHHHHCCCC	13.33	22890988
45	Acetylation	SKIQEYDKASTKANS HHHHHHHHHCCCCCC	43.25	22865919
45	Ubiquitination	SKIQEYDKASTKANS HHHHHHHHHCCCCCC	43.25	15699485
47	Phosphorylation	IQEYDKASTKANSQQ HHHHHHHCCCCCCCC	35.86	25533186
48	Phosphorylation	QEYDKASTKANSQQT HHHHHHCCCCCCCCC	38.75	22890988
71	Phosphorylation	PENLHHASPQPASVP CCCCCCCCCCCCCCC	21.51	28889911
145	Phosphorylation	GTPLSTPSPESGNTF CCCCCCCCCCCCCCC	41.19	28889911
157	Phosphorylation	NTFTDSSSADSDMTS CCCCCCCCCCCCCCC	39.79	28889911
160	Phosphorylation	TDSSSADSDMTSTKK CCCCCCCCCCCCCCC	29.06	16445868
166	Ubiquitination	DSDMTSTKKYVRPPP CCCCCCCCCCCCCCC	41.70	15699485
167	Ubiquitination	SDMTSTKKYVRPPPM CCCCCCCCCCCCCCC	49.41	17644757
176	Phosphorylation	VRPPPMLTSPNDFPN CCCCCCCCCCCCCCH	35.57	17330950
177	Phosphorylation	RPPPMLTSPNDFPNW CCCCCCCCCCCCCHH	20.11	17330950
186	Acetylation	NDFPNWVKTYIKFLQ CCCCHHHHHHHHHHH	27.50	24489116
186	Ubiquitination	NDFPNWVKTYIKFLQ CCCCHHHHHHHHHHH	27.50	17644757
190	Acetylation	NWVKTYIKFLQNSNL HHHHHHHHHHHCCCC	29.61	24489116
203	Phosphorylation	NLGGIIPTVNGKPVP CCCCCCCCCCCEECC	19.05	24909858
228	Ubiquitination	NWVKTYIKFLQNSNL HHHHHHHHHHHCCCC	29.61	17644757
241	Phosphorylation	NLGGIIPTVNGKPVR CCCCEEECCCCEECE	19.05	24909858
245	Acetylation	IIPTVNGKPVRQITD EEECCCCEECEECCH	34.83	24489116
245	Succinylation	IIPTVNGKPVRQITD EEECCCCEECEECCH	34.83	23954790
245	Ubiquitination	IIPTVNGKPVRQITD EEECCCCEECEECCH	34.83	23749301
276	Ubiquitination	QFLPTWVKDILSVDY HCCCHHHHHHHCCCH	30.52	15699485
288	Acetylation	VDYTDIMKILSKSIE CCHHHHHHHHHHHHH	40.61	24489116
288	Ubiquitination	VDYTDIMKILSKSIE CCHHHHHHHHHHHHH	40.61	24961812
292	Acetylation	DIMKILSKSIEKMQS HHHHHHHHHHHHHHH	52.59	22865919
293	Phosphorylation	IMKILSKSIEKMQSD HHHHHHHHHHHHHHC	32.38	21440633
296	Acetylation	ILSKSIEKMQSDTQE HHHHHHHHHHHCCHH	40.34	24489116
299	Phosphorylation	KSIEKMQSDTQEAND HHHHHHHHCCHHHHH	38.84	28132839
301	Phosphorylation	IEKMQSDTQEANDIV HHHHHHCCHHHHHHH	33.29	28132839
318	Phosphorylation	ANLQYNGSTPADAFE HHCEECCCCHHHHHH	27.81	28889911
319	Phosphorylation	NLQYNGSTPADAFET HCEECCCCHHHHHHH	24.72	27214570
327	Ubiquitination	PADAFETKVTNIIDR HHHHHHHHHHHHHHH	39.60	17644757
345	Acetylation	NGIHINNKVACQLIM CCCCCCCHHHHHHHH	27.07	24489116
345	Ubiquitination	NGIHINNKVACQLIM CCCCCCCHHHHHHHH	27.07	17644757
356	Phosphorylation	QLIMRGLSGEYKFLR HHHHCCCCCCHHHHH	32.19	21440633
360	Acetylation	RGLSGEYKFLRYTRH CCCCCCHHHHHHHCH	33.35	24489116
360	Ubiquitination	RGLSGEYKFLRYTRH CCCCCCHHHHHHHCH	33.35	23749301
391	Phosphorylation	IYEEQQGSRNSKPNY HHHHHCCCCCCCCCC	24.77	28889911
395	Ubiquitination	QQGSRNSKPNYRRNP HCCCCCCCCCCCCCC	40.61	22817900
403	Phosphorylation	PNYRRNPSDEKNDSR CCCCCCCCCCCCCCC	63.05	28889911
406	Acetylation	RRNPSDEKNDSRSYT CCCCCCCCCCCCCCC	71.67	24489116
406	Succinylation	RRNPSDEKNDSRSYT CCCCCCCCCCCCCCC	71.67	23954790
409	Phosphorylation	PSDEKNDSRSYTNTT CCCCCCCCCCCCCCC	32.30	17287358
411	Phosphorylation	DEKNDSRSYTNTTKP CCCCCCCCCCCCCCC	40.02	25521595
412	Phosphorylation	EKNDSRSYTNTTKPK CCCCCCCCCCCCCCE	11.69	22890988
413	Phosphorylation	KNDSRSYTNTTKPKV CCCCCCCCCCCCCEE	27.60	21551504
415	Phosphorylation	DSRSYTNTTKPKVIA CCCCCCCCCCCEEEE	28.53	22890988
416	Phosphorylation	SRSYTNTTKPKVIAR CCCCCCCCCCEEEEC	47.63	22890988
417	Acetylation	RSYTNTTKPKVIARN CCCCCCCCCEEEECC	40.58	24489116
417	Succinylation	RSYTNTTKPKVIARN CCCCCCCCCEEEECC	40.58	23954790
417	Ubiquitination	RSYTNTTKPKVIARN CCCCCCCCCEEEECC	40.58	22817900
419	Ubiquitination	YTNTTKPKVIARNPQ CCCCCCCEEEECCCC	48.07	22817900
432	Acetylation	PQKTNNSKSKTARAH CCCCCCCCCCCCHHC	59.08	23572591
434	Acetylation	KTNNSKSKTARAHNV CCCCCCCCCCHHCCC	50.36	23572591
435	Phosphorylation	TNNSKSKTARAHNVS CCCCCCCCCHHCCCC	28.59	21551504
442	Phosphorylation	TARAHNVSTSNNSPS CCHHCCCCCCCCCCC	31.28	25533186
443	Phosphorylation	ARAHNVSTSNNSPST CHHCCCCCCCCCCCC	31.06	25533186
444	Phosphorylation	RAHNVSTSNNSPSTD HHCCCCCCCCCCCCC	26.89	21551504
447	Phosphorylation	NVSTSNNSPSTDNDS CCCCCCCCCCCCCCC	25.20	17330950
449	Phosphorylation	STSNNSPSTDNDSIS CCCCCCCCCCCCCCC	48.49	17330950
450	Phosphorylation	TSNNSPSTDNDSISK CCCCCCCCCCCCCCC	42.05	17330950
454	Phosphorylation	SPSTDNDSISKSTTE CCCCCCCCCCCCCCC	34.71	21551504
456	Phosphorylation	STDNDSISKSTTEPI CCCCCCCCCCCCCCE	25.22	25533186
457	Ubiquitination	TDNDSISKSTTEPIQ CCCCCCCCCCCCCEE	50.59	23749301
458	Phosphorylation	DNDSISKSTTEPIQL CCCCCCCCCCCCEEC	33.50	24909858
459	Phosphorylation	NDSISKSTTEPIQLN CCCCCCCCCCCEECC	38.63	28889911
460	Phosphorylation	DSISKSTTEPIQLNN CCCCCCCCCCEECCC	47.02	21551504
468	Ubiquitination	EPIQLNNKHDLHLGQ CCEECCCCCCCCCCH	37.11	22817900
476	Ubiquitination	HDLHLGQKLTESTVN CCCCCCHHCCHHHCC	56.42	17644757
478	Phosphorylation	LHLGQKLTESTVNHT CCCCHHCCHHHCCCC	34.62	19779198
480	Phosphorylation	LGQKLTESTVNHTNH CCHHCCHHHCCCCCC	32.21	17330950
481	Phosphorylation	GQKLTESTVNHTNHS CHHCCHHHCCCCCCC	21.06	17330950
485	Phosphorylation	TESTVNHTNHSDDEL CHHHCCCCCCCCCCC	29.44	19779198
488	Phosphorylation	TVNHTNHSDDELPGH HCCCCCCCCCCCCCE	49.15	28889911
509	Phosphorylation	ASRTLIRSAHHIHSA CCHHHHHHHHHHHHC	25.59	30377154
515	Phosphorylation	RSAHHIHSASSNPDI HHHHHHHHCCCCCCC	29.28	24909858
517	Phosphorylation	AHHIHSASSNPDINV HHHHHHCCCCCCCCC	33.39	19779198
518	Phosphorylation	HHIHSASSNPDINVV HHHHHCCCCCCCCCC	52.69	24909858
529	Ubiquitination	INVVDAQKRNIPINA CCCCCHHHCCCCCCE	49.48	23749301
549	Ubiquitination	FHFQDNTKTSIKVLH EEEECCCCCEEEEEE	46.67	17644757
553	Ubiquitination	DNTKTSIKVLHTPNI CCCCCEEEEEECCCH	38.21	17644757
581	Ubiquitination	DITACFTKNVLERSD CHHHHCCCCHHHCCC	25.47	17644757
597	Ubiquitination	TVLAPIVKYGDFYWV EEEEEEEECCCEEEE	44.21	17644757
606	Succinylation	GDFYWVSKKYLLPSN CCEEEEECEEECCCC	35.50	23954790
606	Ubiquitination	GDFYWVSKKYLLPSN CCEEEEECEEECCCC	35.50	17644757
607	Ubiquitination	DFYWVSKKYLLPSNI CEEEEECEEECCCCC	33.36	24961812
612	Phosphorylation	SKKYLLPSNISVPTI ECEEECCCCCCCCCC	46.92	30377154
615	Phosphorylation	YLLPSNISVPTINNV EECCCCCCCCCCCCC	26.71	25521595
618	Phosphorylation	PSNISVPTINNVHTS CCCCCCCCCCCCCCC	33.89	28889911
624	Phosphorylation	PTINNVHTSESTRKY CCCCCCCCCCCCCCC	29.88	25521595
627	Phosphorylation	NNVHTSESTRKYPYP CCCCCCCCCCCCCCH	33.02	25521595
630	Ubiquitination	HTSESTRKYPYPFIH CCCCCCCCCCCHHHH	51.14	17644757
653	Ubiquitination	QTIRYSLKNNTITYF CEEEEECCCCEEEEE	42.06	15699485
682	Ubiquitination	CPDCLIGKSTKHRHI CCCCEECCCCCCCCC	48.21	15699485
695	Ubiquitination	HIKGSRLKYQNSYEP CCCCCCCCCCCCCCC	43.62	17644757
719	Ubiquitination	GPVHNLPKSAPSYFI CCCCCCCCCCCCEEE	63.52	17644757
734	Acetylation	SFTDETTKFRWVYPL EEECCCCCEEEEEEC	40.11	24489116
734	Ubiquitination	SFTDETTKFRWVYPL EEECCCCCEEEEEEC	40.11	17644757
761	Ubiquitination	TTILAFIKNQFQASV HHHHHHHHHHHHCEE	37.94	15699485
786	Ubiquitination	YTNRTLHKFLEKNGI CCHHHHHHHHHHCCC	55.55	23749301
790	Ubiquitination	TLHKFLEKNGITPCY HHHHHHHHCCCCCCE	63.72	23749301
850	Phosphorylation	IVRNSLASPKSKKSA HHHHHCCCCCCHHHH	37.85	25752575
888	Ubiquitination	NDHNPNSKIHPRGIP CCCCCCCCCCCCCCC	52.23	23749301
916	Ubiquitination	IIYLPSLKKTVDTTN EEEECCCCEEECCCC	51.22	17644757
917	Ubiquitination	IYLPSLKKTVDTTNY EEECCCCEEECCCCE	60.10	17644757
918	Phosphorylation	YLPSLKKTVDTTNYV EECCCCEEECCCCEE	23.25	27017623
921	Phosphorylation	SLKKTVDTTNYVILQ CCCEEECCCCEEEEC	16.77	27017623
922	Phosphorylation	LKKTVDTTNYVILQG CCEEECCCCEEEECC	21.79	27017623
924	Phosphorylation	KTVDTTNYVILQGKE EEECCCCEEEECCCH	6.18	27017623
930	Ubiquitination	NYVILQGKESRLDQF CEEEECCCHHHHHHC	39.29	24961812
932	Phosphorylation	VILQGKESRLDQFNY EEECCCHHHHHHCCC	41.45	27017623
943	Phosphorylation	QFNYDALTFDEDLNR HCCCCCCCCCHHHHH	30.66	27017623
974	Phosphorylation	SNDLNIESDHDFQSD CCCCCCCCCCCHHHH	36.13	19779198
980	Phosphorylation	ESDHDFQSDIELHPE CCCCCHHHHHCCCHH	40.32	28889911
994	Phosphorylation	EQLRNVLSKAVSPTD HHHHHHHHHCCCCCC	17.81	17330950
995	Ubiquitination	QLRNVLSKAVSPTDS HHHHHHHHCCCCCCC	48.96	17644757
998	Phosphorylation	NVLSKAVSPTDSTPP HHHHHCCCCCCCCCC	27.26	17330950
1000	Phosphorylation	LSKAVSPTDSTPPST HHHCCCCCCCCCCCC	34.77	17330950
1002	Phosphorylation	KAVSPTDSTPPSTHT HCCCCCCCCCCCCCC	45.34	17330950
1003	Phosphorylation	AVSPTDSTPPSTHTE CCCCCCCCCCCCCCH	41.87	17330950
1006	Phosphorylation	PTDSTPPSTHTEDSK CCCCCCCCCCCHHCC	33.74	22890988
1007	Phosphorylation	TDSTPPSTHTEDSKR CCCCCCCCCCHHCCC	38.29	22890988
1009	Phosphorylation	STPPSTHTEDSKRVS CCCCCCCCHHCCCCC	41.39	22890988
1012	Phosphorylation	PSTHTEDSKRVSKTN CCCCCHHCCCCCCCC	19.01	22890988
1013	Ubiquitination	STHTEDSKRVSKTNI CCCCHHCCCCCCCCC	69.96	22817900
1016	Phosphorylation	TEDSKRVSKTNIRAP CHHCCCCCCCCCCCC	37.48	21440633
1017	Ubiquitination	EDSKRVSKTNIRAPR HHCCCCCCCCCCCCC	42.61	22817900
1018	Phosphorylation	DSKRVSKTNIRAPRE HCCCCCCCCCCCCCC	28.50	28889911
1031	Phosphorylation	REVDPNISESNILPS CCCCCCCCHHHCCCC	41.43	25533186
1033	Phosphorylation	VDPNISESNILPSKK CCCCCCHHHCCCCCC	23.52	22890988
1038	Phosphorylation	SESNILPSKKRSSTP CHHHCCCCCCCCCCC	47.57	22890988
1039	Ubiquitination	ESNILPSKKRSSTPQ HHHCCCCCCCCCCCC	50.71	17644757
1040	Ubiquitination	SNILPSKKRSSTPQI HHCCCCCCCCCCCCC	62.95	17644757
1042	Phosphorylation	ILPSKKRSSTPQISD CCCCCCCCCCCCCCC	47.66	21440633
1043	Phosphorylation	LPSKKRSSTPQISDI CCCCCCCCCCCCCCC	48.41	17330950
1044	Phosphorylation	PSKKRSSTPQISDIE CCCCCCCCCCCCCCC	22.06	17330950
1048	Phosphorylation	RSSTPQISDIESTGS CCCCCCCCCCCCCCC	27.56	28889911
1052	Phosphorylation	PQISDIESTGSGGMH CCCCCCCCCCCCCCC	38.10	28889911
1053	Phosphorylation	QISDIESTGSGGMHR CCCCCCCCCCCCCCC	23.68	27017623
1070	Phosphorylation	VPLLAPMSQSNTHES CCEEEECCCCCCCCC	29.42	28889911
1074	Phosphorylation	APMSQSNTHESSHAS EECCCCCCCCCCCCC	32.06	28889911
1077	Phosphorylation	SQSNTHESSHASKSK CCCCCCCCCCCCCCC	21.59	28889911
1081	Phosphorylation	THESSHASKSKDFRH CCCCCCCCCCCCCCC	31.85	28889911
1083	Phosphorylation	ESSHASKSKDFRHSD CCCCCCCCCCCCCCC	34.66	28889911
1089	Phosphorylation	KSKDFRHSDSYSDNE CCCCCCCCCCCCCCC	24.81	20377248
1091	Phosphorylation	KDFRHSDSYSDNETN CCCCCCCCCCCCCCC	29.56	25533186
1092	Phosphorylation	DFRHSDSYSDNETNH CCCCCCCCCCCCCCC	25.65	20377248
1093	Phosphorylation	FRHSDSYSDNETNHT CCCCCCCCCCCCCCC	37.60	17330950
1097	Phosphorylation	DSYSDNETNHTNVPI CCCCCCCCCCCCCCC	38.26	21440633
1100	Phosphorylation	SDNETNHTNVPISST CCCCCCCCCCCCCCC	39.73	17330950
1105	Phosphorylation	NHTNVPISSTGGTNN CCCCCCCCCCCCCCC	18.77	20377248
1106	Phosphorylation	HTNVPISSTGGTNNK CCCCCCCCCCCCCCC	31.62	20377248
1110	Phosphorylation	PISSTGGTNNKTVPQ CCCCCCCCCCCCCCC	36.64	28889911
1119	Phosphorylation	NKTVPQTSEQETEKR CCCCCCCCHHHHHHH	31.84	23749301
1125	Ubiquitination	TSEQETEKRIIHRSP CCHHHHHHHHHHCCC	57.21	22817900
1131	Phosphorylation	EKRIIHRSPSIDTSS HHHHHHCCCCCCCCC	14.61	17330950
1133	Phosphorylation	RIIHRSPSIDTSSSE HHHHCCCCCCCCCCC	34.05	17330950
1136	Phosphorylation	HRSPSIDTSSSESNS HCCCCCCCCCCCCCC	28.92	17287358
1137	Phosphorylation	RSPSIDTSSSESNSL CCCCCCCCCCCCCCC	28.28	28889911
1138	Phosphorylation	SPSIDTSSSESNSLH CCCCCCCCCCCCCCE	39.97	28889911
1139	Phosphorylation	PSIDTSSSESNSLHH CCCCCCCCCCCCCEE	44.82	28889911
1141	Phosphorylation	IDTSSSESNSLHHVV CCCCCCCCCCCEEEE	33.40	19779198
1143	Phosphorylation	TSSSESNSLHHVVPI CCCCCCCCCEEEEEE	38.06	28889911
1151	Ubiquitination	LHHVVPIKTSDTCPK CEEEEEEECCCCCCC	35.59	17644757
1158	Ubiquitination	KTSDTCPKENTEESI ECCCCCCCCCCCCCE	66.79	17644757
1194	Phosphorylation	KELPPINSHQTNSSL CCCCCCCCCCCCCCC	20.07	28889911
1197	Phosphorylation	PPINSHQTNSSLGGI CCCCCCCCCCCCCCC	31.48	28889911
1199	Phosphorylation	INSHQTNSSLGGIGD CCCCCCCCCCCCCCC	30.26	21440633
1200	Phosphorylation	NSHQTNSSLGGIGDS CCCCCCCCCCCCCCC	32.86	25752575
1211	Phosphorylation	IGDSNAYTTINSKKR CCCCCCCCEECCCCC	20.84	19779198
1216	Ubiquitination	AYTTINSKKRSLEDN CCCEECCCCCCCCCC	47.95	15699485
1217	Ubiquitination	YTTINSKKRSLEDNE CCEECCCCCCCCCCC	47.22	15699485
1219	Phosphorylation	TINSKKRSLEDNETE EECCCCCCCCCCCCE	45.02	17330950
1225	Phosphorylation	RSLEDNETEIKVSRD CCCCCCCCEEEEEHH	49.63	28132839
1228	Ubiquitination	EDNETEIKVSRDTWN CCCCCEEEEEHHCCC	28.11	23749301
1230	Phosphorylation	NETEIKVSRDTWNTK CCCEEEEEHHCCCCC	21.31	30377154
1237	Ubiquitination	SRDTWNTKNMRSLEP EHHCCCCCCCCCCCC	45.60	22817900
1258	Ubiquitination	IHLIAAVKAVKSIKP HHHHHHHHHHHCCCC	42.61	17644757
1280	Ubiquitination	DEAITYNKDIKEKEK CCEECCCCCHHHHHH	50.87	23749301
1283	Ubiquitination	ITYNKDIKEKEKYIQ ECCCCCHHHHHHHHH	73.24	22817900
1285	Ubiquitination	YNKDIKEKEKYIQAY CCCCHHHHHHHHHHH	55.28	22817900
1331	Ubiquitination	SMFIFNRKRDGTHKA EEEEEECCCCCCCCE	56.81	17644757
1423	Ubiquitination	KKSLYGLKQSGANWY HHHHHCCHHCCCCHH	37.75	15699485
1425	Phosphorylation	SLYGLKQSGANWYET HHHCCHHCCCCHHHH	37.98	19779198
1430	Phosphorylation	KQSGANWYETIKSYL HHCCCCHHHHHHHHH	11.73	19779198
1434	Ubiquitination	ANWYETIKSYLIKQC CCHHHHHHHHHHHHH	40.23	15699485
1439	Ubiquitination	TIKSYLIKQCGMEEV HHHHHHHHHHCCHHH	36.62	24961812
1478	Ubiquitination	SKDLNANKKIITTLK HCCCCCCHHHHHHHH	42.83	17644757
1479	Ubiquitination	KDLNANKKIITTLKK CCCCCCHHHHHHHHH	38.87	17644757
1485	Ubiquitination	KKIITTLKKQYDTKI HHHHHHHHHHCCCEE	35.42	17644757
1486	Ubiquitination	KIITTLKKQYDTKII HHHHHHHHHCCCEEE	58.14	17644757
1491	Ubiquitination	LKKQYDTKIINLGES HHHHCCCEEEECCCC	38.40	17644757
1512	Ubiquitination	DILGLEIKYQRGKYM EEECEEEEEECCCCC	26.42	17644757
1518	Phosphorylation	IKYQRGKYMKLGMEN EEEECCCCCCCCCCC	11.42	19779198
1520	Acetylation	YQRGKYMKLGMENSL EECCCCCCCCCCCCC	38.51	24489116
1520	Ubiquitination	YQRGKYMKLGMENSL EECCCCCCCCCCCCC	38.51	15699485
1530	Acetylation	MENSLTEKIPKLNVP CCCCCCCCCCCCCCC	60.10	24489116
1530	Ubiquitination	MENSLTEKIPKLNVP CCCCCCCCCCCCCCC	60.10	23749301
1533	Ubiquitination	SLTEKIPKLNVPLNP CCCCCCCCCCCCCCC	57.05	22817900
1541	Ubiquitination	LNVPLNPKGRKLSAP CCCCCCCCCCCCCCC	70.99	22817900
1544	Ubiquitination	PLNPKGRKLSAPGQP CCCCCCCCCCCCCCC	56.30	22817900
1546	Phosphorylation	NPKGRKLSAPGQPGL CCCCCCCCCCCCCCE	35.14	28889911
1576	Ubiquitination	EKVHEMQKLIGLASY HHHHHHHHHHHHHHH	40.54	17644757
1587	Ubiquitination	LASYVGYKFRFDLLY HHHHCCHHHHHHHHH	24.92	22106047
1633	Ubiquitination	DKQLIWHKNKPTEPD CCEEEEECCCCCCCC	52.23	15699485
1635	Ubiquitination	QLIWHKNKPTEPDNK EEEEECCCCCCCCCC	59.11	15699485
1642	Ubiquitination	KPTEPDNKLVAISDA CCCCCCCCEEEEEEC	52.28	24961812
1658	Ubiquitination	YGNQPYYKSQIGNIY CCCCCCEECCCCCEE	30.00	17644757
1670	Ubiquitination	NIYLLNGKVIGGKST CEEEECCEEECCCCC	29.61	17644757
1678	Ubiquitination	VIGGKSTKASLTCTS EECCCCCCEEEEECC	42.97	15699485
1713	Ubiquitination	HLVQELNKKPITKGL HHHHHHHCCCCCCCC	72.97	15699485
1714	Ubiquitination	LVQELNKKPITKGLL HHHHHHCCCCCCCCC	40.35	15699485
1725	Ubiquitination	KGLLTDSKSTISIII CCCCCCCCCEEEEEE	55.20	17644757
1738	Ubiquitination	IISNNEEKFRNRFFG EECCCHHHHHHHHCC	43.37	17644757
1747	Ubiquitination	RNRFFGTKAMRLRDE HHHHCCHHHCHHHHC	40.33	23749301
1768	Ubiquitination	HVCYIETKKNIADVM EEEEEECCCCHHHHH	30.91	17644757
1769	Ubiquitination	VCYIETKKNIADVMT EEEEECCCCHHHHHC	62.09	23749301
1776	Phosphorylation	KNIADVMTKPLPIKT CCHHHHHCCCCCCCC	29.38	20377248
1777	Ubiquitination	NIADVMTKPLPIKTF CHHHHHCCCCCCCCC	26.85	23749301
1782	Ubiquitination	MTKPLPIKTFKLLTN HCCCCCCCCCHHHHC	46.07	22817900
1785	Ubiquitination	PLPIKTFKLLTNKWI CCCCCCCHHHHCCCC	48.06	15699485

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of YH11B_YEAST !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of YH11B_YEAST !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of YH11B_YEAST !!

Protein-Protein Interaction

Oops, there are no PPI records of YH11B_YEAST !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.

Related Literatures of Post-Translational Modification

Acetylation

"Quantitative phosphoproteomics applied to the yeast pheromonesignaling pathway.";
Gruhler A., Olsen J.V., Mohammed S., Mortensen P., Faergeman N.J.,Mann M., Jensen O.N.;
Mol. Cell. Proteomics 4:310-327(2005).
Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT MET-1, PHOSPHORYLATION [LARGESCALE ANALYSIS] AT SER-13, AND MASS SPECTROMETRY.
PubMed: 15665377

Phosphorylation

"Quantitative phosphoproteomics applied to the yeast pheromonesignaling pathway.";
Gruhler A., Olsen J.V., Mohammed S., Mortensen P., Faergeman N.J.,Mann M., Jensen O.N.;
Mol. Cell. Proteomics 4:310-327(2005).
Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT MET-1, PHOSPHORYLATION [LARGESCALE ANALYSIS] AT SER-13, AND MASS SPECTROMETRY.
PubMed: 15665377