RIX7_YEAST - dbPTM
RIX7_YEAST - PTM Information in dbPTM
Basic Information of Protein
UniProt ID RIX7_YEAST
UniProt AC Q07844
Protein Name Ribosome biogenesis ATPase RIX7
Gene Name RIX7
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length 837
Subcellular Localization Nucleus, nucleolus .
Protein Description Involved in ribosome biogenesis. Seems to be required for restructuring nucleoplasmic 60S pre-ribosomal particles to make them competent for nuclear export..
Protein Sequence MVKVKSKKNSLTSSLDNKIVDLIYRLLEEKTLDRKRSLRQESQGEEGENNEGEEDEDIFESMFFAKDLTAGEIFTFCLTKDLSLQRVKKVVLQKTIDRMLKDVIESELEEFGSYPGYNNEEEEKPSLEEELAKKNMMIERDTNEMNKRITSTWSKSGSVSESITETDDPKTEEVKKSKKRSKEGTCKVKRQKIKEDRSPPNSSLKSLGGMDDVVAQLMELIGLPILHPEIFLSTGVEPPRGVLLHGPPGCGKTSIANALAGELQVPFISISAPSVVSGMSGESEKKIRDLFDEARSLAPCLVFFDEIDAITPKRDGGAQREMERRIVAQLLTSMDELTMEKTNGKPVIIIGATNRPDSLDAALRRAGRFDREICLNVPNEVSRLHILKKMSDNLKIDGAIDFAKLAKLTPGFVGADLKALVTAAGTCAIKRIFQTYANIKSTPTTATDSSEDNMEIDETANGDESSLKNTANMIDPLPLSVVQQFIRNYPEPLSGEQLSLLSIKYEDFLKALPTIQPTAKREGFATVPDVTWANVGALQRVRLELNMAIVQPIKRPELYEKVGISAPGGVLLWGPPGCGKTLLAKAVANESRANFISIKGPELLNKYVGESERSIRQVFTRARASVPCVIFFDELDALVPRRDTSLSESSSRVVNTLLTELDGLNDRRGIFVIGATNRPDMIDPAMLRPGRLDKSLFIELPNTEEKLDIIKTLTKSHGTPLSSDVDFEEIIRNEKCNNFSGADLAALVRESSVLALKRKFFQSEEIQSVLDNDLDKEFEDLSVGVSGEEIIVTMSDFRSALRKIKPSVSDKDRLKYDRLNKKMGLTEEMKDAEEMKQ
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
8UbiquitinationMVKVKSKKNSLTSSL
CCCCCCCCCCCCHHH		59.8823749301
10PhosphorylationKVKSKKNSLTSSLDN
CCCCCCCCCCHHHHH		41.7320377248
12PhosphorylationKSKKNSLTSSLDNKI
CCCCCCCCHHHHHHH		18.9819823750
14PhosphorylationKKNSLTSSLDNKIVD
CCCCCCHHHHHHHHH		34.2119823750
42PhosphorylationKRSLRQESQGEEGEN
HHHHHHHHCCCCCCC		34.8428889911
106PhosphorylationMLKDVIESELEEFGS
HHHHHHHHHHHHHCC		36.0421440633
113PhosphorylationSELEEFGSYPGYNNE
HHHHHHCCCCCCCCC		33.2124961812
114PhosphorylationELEEFGSYPGYNNEE
HHHHHCCCCCCCCCC		10.8924961812
150PhosphorylationNEMNKRITSTWSKSG
HHHHHHHHHHCCCCC		24.9221440633
151PhosphorylationEMNKRITSTWSKSGS
HHHHHHHHHCCCCCC		26.0530377154
154PhosphorylationKRITSTWSKSGSVSE
HHHHHHCCCCCCCCC		19.6130377154
156PhosphorylationITSTWSKSGSVSESI
HHHHCCCCCCCCCCC		30.6821551504
158PhosphorylationSTWSKSGSVSESITE
HHCCCCCCCCCCCCC		29.5717330950
160PhosphorylationWSKSGSVSESITETD
CCCCCCCCCCCCCCC		27.5921440633
162PhosphorylationKSGSVSESITETDDP
CCCCCCCCCCCCCCC		27.5728889911
164PhosphorylationGSVSESITETDDPKT
CCCCCCCCCCCCCCC		41.9521440633
166PhosphorylationVSESITETDDPKTEE
CCCCCCCCCCCCCHH		36.7321440633
170AcetylationITETDDPKTEEVKKS
CCCCCCCCCHHHHHH		75.4724489116
271PhosphorylationQVPFISISAPSVVSG
CCCEEEECCCHHHCC		27.6025882841
404AcetylationDGAIDFAKLAKLTPG
CCCCCHHHHCCCCCC		49.3124489116
441PhosphorylationQTYANIKSTPTTATD
HHHCCCCCCCCCCCC		35.5030377154
444PhosphorylationANIKSTPTTATDSSE
CCCCCCCCCCCCCCC		29.2030377154
445PhosphorylationNIKSTPTTATDSSED
CCCCCCCCCCCCCCC		28.8523749301
447PhosphorylationKSTPTTATDSSEDNM
CCCCCCCCCCCCCCC		34.0320377248
449PhosphorylationTPTTATDSSEDNMEI
CCCCCCCCCCCCCEE		31.1320377248
450PhosphorylationPTTATDSSEDNMEID
CCCCCCCCCCCCEEC		52.3523749301
752PhosphorylationAALVRESSVLALKRK
HHHHHHHHHHHHHHH		19.1927214570
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of RIX7_YEAST !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of RIX7_YEAST !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of RIX7_YEAST !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
AMN1_YEASTAMN1physical
14690591
AXL2_YEASTAXL2physical
14690591
IMH1_YEASTIMH1physical
14690591
PEX19_YEASTPEX19physical
14690591
6P22_YEASTPFK27physical
14690591
RGT2_YEASTRGT2physical
14690591
RPA1_YEASTRPA190physical
14690591
SST2_YEASTSST2physical
14690591
TRX1_YEASTTRX1physical
14690591
TRX2_YEASTTRX2physical
14690591
YL11B_YEASTYLR035C-Aphysical
14690591
RIC1_YEASTRIC1physical
14690591
RAX2_YEASTRAX2physical
14690591
RPA2_YEASTRPA135physical
11805826
RPA1_YEASTRPA190physical
11805826
PRS8_YEASTRPT6physical
11805826
RL3_YEASTRPL3physical
16429126
RL7B_YEASTRPL7Bphysical
16429126
RS18A_YEASTRPS18Aphysical
16429126
RS18B_YEASTRPS18Aphysical
16429126
RL8B_YEASTRPL8Bphysical
16429126
RL13B_YEASTRPL13Bphysical
16429126
RL2A_YEASTRPL2Aphysical
16429126
RL2B_YEASTRPL2Aphysical
16429126
RL7A_YEASTRPL7Aphysical
16429126
RIX7_YEASTRIX7physical
18467557
MEC3_YEASTMEC3physical
18467557
NSA1_YEASTNSA1genetic
18559667
NSA1_YEASTNSA1physical
18559667
RIX7_YEASTRIX7physical
22615397
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of RIX7_YEAST

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Related Literatures of Post-Translational Modification
Phosphorylation
ReferencePubMed
"A multidimensional chromatography technology for in-depthphosphoproteome analysis.";
Albuquerque C.P., Smolka M.B., Payne S.H., Bafna V., Eng J., Zhou H.;
Mol. Cell. Proteomics 7:1389-1396(2008).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-10, AND MASSSPECTROMETRY.

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