YL11B_YEAST - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: YL11B_YEAST
• UniProt AC: Q12088
• Protein Name: Transposon Ty1-LR1 Gag-Pol polyprotein
• Gene Name: TY1B-LR1
• Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
• Sequence Length: 1755
• Subcellular Localization: Cytoplasm. Nucleus.
• Protein Description: Capsid protein (CA) is the structural component of the virus-like particle (VLP), forming the shell that encapsulates the retrotransposons dimeric RNA genome. The particles are assembled from trimer-clustered units and there are holes in the capsid shells that allow for the diffusion of macromolecules. CA has also nucleocapsid-like chaperone activity, promoting primer tRNA(i)-Met annealing to the multipartite primer-binding site (PBS), dimerization of Ty1 RNA and initiation of reverse transcription (By similarity).; The aspartyl protease (PR) mediates the proteolytic cleavages of the Gag and Gag-Pol polyproteins after assembly of the VLP.; Reverse transcriptase/ribonuclease H (RT) is a multifunctional enzyme that catalyzes the conversion of the retro-elements RNA genome into dsDNA within the VLP. The enzyme displays a DNA polymerase activity that can copy either DNA or RNA templates, and a ribonuclease H (RNase H) activity that cleaves the RNA strand of RNA-DNA heteroduplexes during plus-strand synthesis and hydrolyzes RNA primers. The conversion leads to a linear dsDNA copy of the retrotransposon that includes long terminal repeats (LTRs) at both ends (By similarity).; Integrase (IN) targets the VLP to the nucleus, where a subparticle preintegration complex (PIC) containing at least integrase and the newly synthesized dsDNA copy of the retrotransposon must transit the nuclear membrane. Once in the nucleus, integrase performs the integration of the dsDNA into the host genome (By similarity)..
• Protein Sequence: MESQQLSNYPHISHGSACASVTSKEVHTNQDPLDVSASKIQEYDKASTKANSQQTTTPASSAVPENPHHASPQPASVPPPQNGPYPQQCMMTQNQANPSGWSFYGHPSMIPYTPYQMSPMYFPPGPQSQFPQYPSSVGTPLSTPSPESGNTFTDSSSADSDMTSTKKYVRPPPMLTSPNDFPNWVKTYIKFLQNSNLGGIIPTVNGKPVRQITDDELTFLYNTFQIFAPSQFLPTWVKDILSVDYTDIMKILSKSIEKMQSDTQEANDIVTLANLQYNGSTPADAFETKVTNIIDRLNNNGIHINNKVACQLIMRGLSGEYKFLRYTRHRHLNMTVAELFLDIHAIYEEQQGSRNSKPNYRRNPSDEKNDSRSYTNTTKPKVIARNPQKTNNSKSKTARAHNVSTSNNSPSTDNDSISKSTTEPIQLNNKHDLHLGQKLTESTVNHTNHSDDELPGHLLLDSGASRTLIRSAHHIHSASSNPDINVVDAQKRNIPINAIGDLQFHFQDNTKTSIKVLHTPNIAYDLLSLNELAAVDITACFTKNVLERSDGTVLAPIVKYGDFYWVSKKYLLPSNISVPTINNVHTSESTRKYPYPFIHRMLAHANAQTIRYSLKNNTITYFNESDVDWSSAIDYQCPDCLIGKSTKHRHIKGSRLKYQNSYEPFQYLHTDIFGPVHNLPKSAPSYFISFTDETTKFRWVYPLHDRREDSILDVFTTILAFIKNQFQASVLVIQMDRGSEYTNRTLHKFLEKNGITPCYTTTADSRAHGVAERLNRTLLDDCRTQLQCSGLPNHLWFSAIEFSTIVRNSLASPKSKKSARQHAGLAGLDISTLLPFGQPVIVNDHNPNSKIHPRGIPGYALHPSRNSYGYIIYLPSLKKTVDTTNYVILQGKESRLDQFNYDALTFDEDLNRLTASYQSFIASNEIQQSDDLNIESDHDFQSDIELHPEQPRNVLSKAVSPTDSTPPSTHTEDSKRVSKTNIRAPREVDPNISESNILPSKKRSSTPQISDIESTGSGGMHRLDVPLLAPMSQSNTHESSHASKSKDFRHSDSYSDNETNHTNVPISSTGGTNNKTVPQTSEQETEKRIIHRSPSIDTSSSESNSLHHVVPIKTSDTCPKENTEESIIADLPLPDLPPEPPTELSDSFKELPPINSHQTNSSLGGIGDSNAYTTINSKKRSLEDNETEIKVSRDTWNTKNMRSLEPPRSKKRIHLIAAVKAVKSIKPIRTTLRYDEAITYNKDIKEKEKYIQAYHKEVNQLLKMKTWDTDRYYDRKEIDPKRVINSMFIFNRKRGGTHKARFVARGDIQHPDTYDPGMQSNTVHHYALMTSLSLASDNNYYITQLDISSAYLYADIKEELYIRPPPHLGMNDKLIRLKKSLYGLKQSGANWYETIKSYLIKQCGMEEVRGWSCVFKNSQVTICLFVDDMILFSKDLNANKKIITTLKKQYDTKIINLGESDNEIQYDILGLEIKYQRGKYMKLGMENSLTEKIPKLNVPLNPKGRKLSAPGQPGLYIDQQELELEEDDYKMKVHEMQKLIGLASYVGYKFRFDLLYYINTLAQHILFPSKQVLDMTYELIQFIWNTRDKQLIWHKSKPVKPTNKLVVISDASYGNQPYYKSQIGNIYLLNGKVIGGKSTKASLTCTSTTEAEIHAISESVPLLNNLSHLVQELNKKPITKGLLTDSKSTISIIISNNEEKFRNRFFGTKAMRLRDEVSGNHLHVCYIETKKNIADVMTKPLPIKTFKLLTNKWIH

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
1	Acetylation	-------MESQQLSN -------CCCCCCCC	46.79	-
13	Phosphorylation	LSNYPHISHGSACAS CCCCCCCCCCCCCEE	20.82	15665377
15	Ubiquitination	NYPHISHGSACASVT CCCCCCCCCCCEECC	15.33	15699485
16	Phosphorylation	YPHISHGSACASVTS CCCCCCCCCCEECCC	18.10	28889911
20	Phosphorylation	SHGSACASVTSKEVH CCCCCCEECCCCCCC	26.30	28889911
22	Phosphorylation	GSACASVTSKEVHTN CCCCEECCCCCCCCC	31.42	28889911
23	Phosphorylation	SACASVTSKEVHTNQ CCCEECCCCCCCCCC	25.35	19823750
28	Phosphorylation	VTSKEVHTNQDPLDV CCCCCCCCCCCCCCC	39.49	28889911
36	Phosphorylation	NQDPLDVSASKIQEY CCCCCCCCHHHHHHH	26.88	25521595
38	Phosphorylation	DPLDVSASKIQEYDK CCCCCCHHHHHHHHH	23.84	25521595
43	Phosphorylation	SASKIQEYDKASTKA CHHHHHHHHHHCCCC	13.33	22890988
44	Ubiquitination	ASKIQEYDKASTKAN HHHHHHHHHHCCCCC	39.01	15699485
47	Phosphorylation	IQEYDKASTKANSQQ HHHHHHHCCCCCCCC	35.86	25533186
48	Phosphorylation	QEYDKASTKANSQQT HHHHHHCCCCCCCCC	38.75	22890988
57	Ubiquitination	ANSQQTTTPASSAVP CCCCCCCCCCHHCCC	21.90	17644757
71	Phosphorylation	PENPHHASPQPASVP CCCCCCCCCCCCCCC	21.51	28889911
81	Ubiquitination	PASVPPPQNGPYPQQ CCCCCCCCCCCCCCC	73.60	17644757
96	Ubiquitination	CMMTQNQANPSGWSF CCCCCCCCCCCCCCC	37.13	17644757
123	Ubiquitination	QMSPMYFPPGPQSQF CCCCCCCCCCCHHHC	18.56	15699485
145	Phosphorylation	GTPLSTPSPESGNTF CCCCCCCCCCCCCCC	41.19	28889911
148	Ubiquitination	LSTPSPESGNTFTDS CCCCCCCCCCCCCCC	40.50	23749301
152	Ubiquitination	SPESGNTFTDSSSAD CCCCCCCCCCCCCCC	9.18	23749301
157	Phosphorylation	NTFTDSSSADSDMTS CCCCCCCCCCCCCCC	39.79	28889911
160	Phosphorylation	TDSSSADSDMTSTKK CCCCCCCCCCCCCCC	29.06	16445868
176	Phosphorylation	VRPPPMLTSPNDFPN CCCCCCCCCCCCCCH	35.57	17330950
177	Phosphorylation	RPPPMLTSPNDFPNW CCCCCCCCCCCCCHH	20.11	17330950
203	Phosphorylation	NLGGIIPTVNGKPVR CCCCEEECCCCEECE	19.05	24909858
250	Ubiquitination	VDYTDIMKILSKSIE CCHHHHHHHHHHHHH	40.61	23749301
255	Phosphorylation	IMKILSKSIEKMQSD HHHHHHHHHHHHHHC	32.38	21440633
261	Phosphorylation	KSIEKMQSDTQEAND HHHHHHHHCCHHHHH	38.84	28132839
263	Phosphorylation	IEKMQSDTQEANDIV HHHHHHCCHHHHHHH	33.29	28132839
278	Ubiquitination	TLANLQYNGSTPADA HHHHCEECCCCHHHH	25.61	17644757
279	Ubiquitination	LANLQYNGSTPADAF HHHCEECCCCHHHHH	28.15	17644757
280	Phosphorylation	ANLQYNGSTPADAFE HHCEECCCCHHHHHH	27.81	28889911
281	Phosphorylation	NLQYNGSTPADAFET HCEECCCCHHHHHHH	24.72	27214570
292	Ubiquitination	AFETKVTNIIDRLNN HHHHHHHHHHHHHHH	32.00	24961812
318	Phosphorylation	QLIMRGLSGEYKFLR HHHHCCCCCCHHHHH	32.19	21440633
353	Phosphorylation	IYEEQQGSRNSKPNY HHHHHCCCCCCCCCC	24.77	28889911
357	Ubiquitination	QQGSRNSKPNYRRNP HCCCCCCCCCCCCCC	40.61	17644757
365	Phosphorylation	PNYRRNPSDEKNDSR CCCCCCCCCCCCCCC	63.05	28889911
371	Phosphorylation	PSDEKNDSRSYTNTT CCCCCCCCCCCCCCC	32.30	17287358
373	Phosphorylation	DEKNDSRSYTNTTKP CCCCCCCCCCCCCCC	40.02	25521595
374	Phosphorylation	EKNDSRSYTNTTKPK CCCCCCCCCCCCCCE	11.69	22890988
375	Phosphorylation	KNDSRSYTNTTKPKV CCCCCCCCCCCCCEE	27.60	21551504
375	Ubiquitination	KNDSRSYTNTTKPKV CCCCCCCCCCCCCEE	27.60	22817900
377	Phosphorylation	DSRSYTNTTKPKVIA CCCCCCCCCCCEEEE	28.53	22890988
378	Phosphorylation	SRSYTNTTKPKVIAR CCCCCCCCCCEEEEC	47.63	22890988
379	Ubiquitination	RSYTNTTKPKVIARN CCCCCCCCCEEEECC	40.58	22817900
397	Phosphorylation	TNNSKSKTARAHNVS CCCCCCCCCHHCCCC	28.59	21551504
401	Ubiquitination	KSKTARAHNVSTSNN CCCCCHHCCCCCCCC	29.66	17644757
402	Ubiquitination	SKTARAHNVSTSNNS CCCCHHCCCCCCCCC	28.57	17644757
404	Phosphorylation	TARAHNVSTSNNSPS CCHHCCCCCCCCCCC	31.28	25533186
405	Phosphorylation	ARAHNVSTSNNSPST CHHCCCCCCCCCCCC	31.06	25533186
406	Phosphorylation	RAHNVSTSNNSPSTD HHCCCCCCCCCCCCC	26.89	21551504
409	Phosphorylation	NVSTSNNSPSTDNDS CCCCCCCCCCCCCCC	25.20	17330950
411	Phosphorylation	STSNNSPSTDNDSIS CCCCCCCCCCCCCCC	48.49	17330950
412	Phosphorylation	TSNNSPSTDNDSISK CCCCCCCCCCCCCCC	42.05	17330950
416	Phosphorylation	SPSTDNDSISKSTTE CCCCCCCCCCCCCCC	34.71	21551504
418	Phosphorylation	STDNDSISKSTTEPI CCCCCCCCCCCCCCE	25.22	25533186
420	Phosphorylation	DNDSISKSTTEPIQL CCCCCCCCCCCCEEC	33.50	24909858
421	Phosphorylation	NDSISKSTTEPIQLN CCCCCCCCCCCEECC	38.63	28889911
422	Phosphorylation	DSISKSTTEPIQLNN CCCCCCCCCCEECCC	47.02	21551504
440	Phosphorylation	LHLGQKLTESTVNHT CCCCHHCCHHHCCCC	34.62	19779198
442	Phosphorylation	LGQKLTESTVNHTNH CCHHCCHHHCCCCCC	32.21	17330950
443	Phosphorylation	GQKLTESTVNHTNHS CHHCCHHHCCCCCCC	21.06	17330950
447	Phosphorylation	TESTVNHTNHSDDEL CHHHCCCCCCCCCCC	29.44	19779198
450	Phosphorylation	TVNHTNHSDDELPGH HCCCCCCCCCCCCCE	49.15	28889911
471	Phosphorylation	ASRTLIRSAHHIHSA CCHHHHHHHHHHHHC	25.59	30377154
477	Phosphorylation	RSAHHIHSASSNPDI HHHHHHHHCCCCCCC	29.28	24909858
479	Phosphorylation	AHHIHSASSNPDINV HHHHHHCCCCCCCCC	33.39	19779198
480	Phosphorylation	HHIHSASSNPDINVV HHHHHCCCCCCCCCC	52.69	24909858
487	Ubiquitination	SNPDINVVDAQKRNI CCCCCCCCCHHHCCC	4.34	22817900
513	Ubiquitination	FQDNTKTSIKVLHTP EECCCCCEEEEEECC	23.20	17644757
520	Ubiquitination	SIKVLHTPNIAYDLL EEEEEECCCHHHHHC	21.34	17644757
574	Phosphorylation	SKKYLLPSNISVPTI ECEEECCCCCCCCCC	46.92	30377154
577	Phosphorylation	YLLPSNISVPTINNV EECCCCCCCCCCCCC	26.71	25521595
578	Ubiquitination	LLPSNISVPTINNVH ECCCCCCCCCCCCCC	4.25	15699485
579	Ubiquitination	LPSNISVPTINNVHT CCCCCCCCCCCCCCC	22.29	15699485
580	Phosphorylation	PSNISVPTINNVHTS CCCCCCCCCCCCCCC	33.89	28889911
586	Phosphorylation	PTINNVHTSESTRKY CCCCCCCCCCCCCCC	29.88	25521595
589	Phosphorylation	NNVHTSESTRKYPYP CCCCCCCCCCCCCCH	33.02	25521595
590	Ubiquitination	NVHTSESTRKYPYPF CCCCCCCCCCCCCHH	27.42	23749301
599	Ubiquitination	KYPYPFIHRMLAHAN CCCCHHHHHHHHHCC	14.96	22817900
620	Ubiquitination	SLKNNTITYFNESDV ECCCCEEEEEEHHCC	21.74	17644757
642	Ubiquitination	YQCPDCLIGKSTKHR CCCCCCEECCCCCCC	9.09	23749301
645	Ubiquitination	PDCLIGKSTKHRHIK CCCEECCCCCCCCCC	37.16	22817900
647	Ubiquitination	CLIGKSTKHRHIKGS CEECCCCCCCCCCCC	45.81	22817900
663	Ubiquitination	LKYQNSYEPFQYLHT CCCCCCCCCHHHEEC	39.19	22817900
665	Ubiquitination	YQNSYEPFQYLHTDI CCCCCCCHHHEECCC	5.08	22817900
693	Ubiquitination	YFISFTDETTKFRWV EEEEEECCCCCEEEE	56.15	17644757
785	Ubiquitination	LLDDCRTQLQCSGLP HHHHHHHHHHHCCCC	15.35	15699485
796	Ubiquitination	SGLPNHLWFSAIEFS CCCCCCEEEEEHHHH	4.24	15699485
801	Ubiquitination	HLWFSAIEFSTIVRN CEEEEEHHHHHHHHH	33.01	24961812
812	Phosphorylation	IVRNSLASPKSKKSA HHHHHCCCCCCHHHH	37.85	25752575
840	Ubiquitination	LLPFGQPVIVNDHNP HCCCCCCEEECCCCC	6.16	17644757
841	Ubiquitination	LPFGQPVIVNDHNPN CCCCCCEEECCCCCC	2.81	17644757
847	Ubiquitination	VIVNDHNPNSKIHPR EEECCCCCCCCCCCC	42.95	17644757
848	Ubiquitination	IVNDHNPNSKIHPRG EECCCCCCCCCCCCC	62.34	17644757
853	Ubiquitination	NPNSKIHPRGIPGYA CCCCCCCCCCCCCEE	39.40	17644757
874	Ubiquitination	SYGYIIYLPSLKKTV CCEEEEEECCCCEEE	1.31	17644757
880	Phosphorylation	YLPSLKKTVDTTNYV EECCCCEEECCCCEE	23.25	27017623
882	Ubiquitination	PSLKKTVDTTNYVIL CCCCEEECCCCEEEE	53.71	15699485
883	Phosphorylation	SLKKTVDTTNYVILQ CCCEEECCCCEEEEC	16.77	27017623
884	Phosphorylation	LKKTVDTTNYVILQG CCEEECCCCEEEECC	21.79	27017623
886	Phosphorylation	KTVDTTNYVILQGKE EEECCCCEEEECCCH	6.18	27017623
892	Ubiquitination	NYVILQGKESRLDQF CEEEECCCHHHHHHC	39.29	23749301
894	Phosphorylation	VILQGKESRLDQFNY EEECCCHHHHHHCCC	41.45	27017623
895	Ubiquitination	ILQGKESRLDQFNYD EECCCHHHHHHCCCC	43.29	22817900
903	Ubiquitination	LDQFNYDALTFDEDL HHHCCCCCCCCCHHH	9.72	22817900
905	Phosphorylation	QFNYDALTFDEDLNR HCCCCCCCCCHHHHH	30.66	27017623
906	Ubiquitination	FNYDALTFDEDLNRL CCCCCCCCCHHHHHH	11.43	22817900
938	Ubiquitination	DLNIESDHDFQSDIE CCCCCCCCCHHHCCC	47.25	17644757
942	Phosphorylation	ESDHDFQSDIELHPE CCCCCHHHCCCCCCC	40.32	28889911
949	Ubiquitination	SDIELHPEQPRNVLS HCCCCCCCCCCCHHH	63.57	22106047
956	Phosphorylation	EQPRNVLSKAVSPTD CCCCCHHHHCCCCCC	17.81	17330950
960	Phosphorylation	NVLSKAVSPTDSTPP CHHHHCCCCCCCCCC	27.26	17330950
962	Phosphorylation	LSKAVSPTDSTPPST HHHCCCCCCCCCCCC	34.77	17330950
964	Phosphorylation	KAVSPTDSTPPSTHT HCCCCCCCCCCCCCC	45.34	17330950
965	Phosphorylation	AVSPTDSTPPSTHTE CCCCCCCCCCCCCCH	41.87	17330950
968	Phosphorylation	PTDSTPPSTHTEDSK CCCCCCCCCCCHHCC	33.74	22890988
969	Phosphorylation	TDSTPPSTHTEDSKR CCCCCCCCCCHHCCC	38.29	22890988
971	Phosphorylation	STPPSTHTEDSKRVS CCCCCCCCHHCCCCC	41.39	22890988
974	Phosphorylation	PSTHTEDSKRVSKTN CCCCCHHCCCCCCCC	19.01	22890988
978	Phosphorylation	TEDSKRVSKTNIRAP CHHCCCCCCCCCCCC	37.48	21440633
980	Phosphorylation	DSKRVSKTNIRAPRE HCCCCCCCCCCCCCC	28.50	28889911
993	Phosphorylation	REVDPNISESNILPS CCCCCCCCHHHCCCC	41.43	25533186
995	Phosphorylation	VDPNISESNILPSKK CCCCCCHHHCCCCCC	23.52	22890988
1000	Phosphorylation	SESNILPSKKRSSTP CHHHCCCCCCCCCCC	47.57	22890988
1004	Phosphorylation	ILPSKKRSSTPQISD CCCCCCCCCCCCCCC	47.66	21440633
1004	Ubiquitination	ILPSKKRSSTPQISD CCCCCCCCCCCCCCC	47.66	17644757
1005	Phosphorylation	LPSKKRSSTPQISDI CCCCCCCCCCCCCCC	48.41	17330950
1006	Phosphorylation	PSKKRSSTPQISDIE CCCCCCCCCCCCCCC	22.06	17330950
1010	Phosphorylation	RSSTPQISDIESTGS CCCCCCCCCCCCCCC	27.56	28889911
1014	Phosphorylation	PQISDIESTGSGGMH CCCCCCCCCCCCCCC	38.10	28889911
1015	Phosphorylation	QISDIESTGSGGMHR CCCCCCCCCCCCCCC	23.68	27017623
1020	Ubiquitination	ESTGSGGMHRLDVPL CCCCCCCCCCCCCCE	1.57	17644757
1032	Phosphorylation	VPLLAPMSQSNTHES CCEEEECCCCCCCCC	29.42	28889911
1032	Ubiquitination	VPLLAPMSQSNTHES CCEEEECCCCCCCCC	29.42	17644757
1036	Phosphorylation	APMSQSNTHESSHAS EECCCCCCCCCCCCC	32.06	28889911
1039	Phosphorylation	SQSNTHESSHASKSK CCCCCCCCCCCCCCC	21.59	28889911
1040	Ubiquitination	QSNTHESSHASKSKD CCCCCCCCCCCCCCC	21.79	15699485
1043	Phosphorylation	THESSHASKSKDFRH CCCCCCCCCCCCCCC	31.85	28889911
1045	Phosphorylation	ESSHASKSKDFRHSD CCCCCCCCCCCCCCC	34.66	28889911
1051	Phosphorylation	KSKDFRHSDSYSDNE CCCCCCCCCCCCCCC	24.81	20377248
1053	Phosphorylation	KDFRHSDSYSDNETN CCCCCCCCCCCCCCC	29.56	25533186
1054	Phosphorylation	DFRHSDSYSDNETNH CCCCCCCCCCCCCCC	25.65	20377248
1055	Phosphorylation	FRHSDSYSDNETNHT CCCCCCCCCCCCCCC	37.60	17330950
1059	Phosphorylation	DSYSDNETNHTNVPI CCCCCCCCCCCCCCC	38.26	21440633
1062	Phosphorylation	SDNETNHTNVPISST CCCCCCCCCCCCCCC	39.73	17330950
1067	Phosphorylation	NHTNVPISSTGGTNN CCCCCCCCCCCCCCC	18.77	20377248
1068	Phosphorylation	HTNVPISSTGGTNNK CCCCCCCCCCCCCCC	31.62	20377248
1072	Phosphorylation	PISSTGGTNNKTVPQ CCCCCCCCCCCCCCC	36.64	28889911
1075	Ubiquitination	STGGTNNKTVPQTSE CCCCCCCCCCCCCCH	53.63	15699485
1076	Ubiquitination	TGGTNNKTVPQTSEQ CCCCCCCCCCCCCHH	39.27	15699485
1081	Phosphorylation	NKTVPQTSEQETEKR CCCCCCCCHHHHHHH	31.84	23749301
1087	Ubiquitination	TSEQETEKRIIHRSP CCHHHHHHHHHHCCC	57.21	17644757
1093	Phosphorylation	EKRIIHRSPSIDTSS HHHHHHCCCCCCCCC	14.61	17330950
1095	Phosphorylation	RIIHRSPSIDTSSSE HHHHCCCCCCCCCCC	34.05	17330950
1098	Phosphorylation	HRSPSIDTSSSESNS HCCCCCCCCCCCCCC	28.92	17287358
1099	Phosphorylation	RSPSIDTSSSESNSL CCCCCCCCCCCCCCC	28.28	28889911
1100	Phosphorylation	SPSIDTSSSESNSLH CCCCCCCCCCCCCCE	39.97	28889911
1100	Ubiquitination	SPSIDTSSSESNSLH CCCCCCCCCCCCCCE	39.97	17644757
1101	Phosphorylation	PSIDTSSSESNSLHH CCCCCCCCCCCCCEE	44.82	28889911
1103	Phosphorylation	IDTSSSESNSLHHVV CCCCCCCCCCCEEEE	33.40	19779198
1105	Phosphorylation	TSSSESNSLHHVVPI CCCCCCCCCEEEEEE	38.06	28889911
1109	Ubiquitination	ESNSLHHVVPIKTSD CCCCCEEEEEEECCC	3.69	23749301
1130	Ubiquitination	TEESIIADLPLPDLP CCCCEEECCCCCCCC	38.11	17644757
1131	Ubiquitination	EESIIADLPLPDLPP CCCEEECCCCCCCCC	3.29	23749301
1139	Ubiquitination	PLPDLPPEPPTELSD CCCCCCCCCCCCCCC	63.07	23749301
1144	Ubiquitination	PPEPPTELSDSFKEL CCCCCCCCCCCCCCC	8.30	22817900
1147	Ubiquitination	PPTELSDSFKELPPI CCCCCCCCCCCCCCC	34.54	15699485
1156	Phosphorylation	KELPPINSHQTNSSL CCCCCCCCCCCCCCC	20.07	28889911
1159	Phosphorylation	PPINSHQTNSSLGGI CCCCCCCCCCCCCCC	31.48	28889911
1161	Phosphorylation	INSHQTNSSLGGIGD CCCCCCCCCCCCCCC	30.26	21440633
1162	Phosphorylation	NSHQTNSSLGGIGDS CCCCCCCCCCCCCCC	32.86	25752575
1173	Phosphorylation	IGDSNAYTTINSKKR CCCCCCCCEECCCCC	20.84	19779198
1181	Phosphorylation	TINSKKRSLEDNETE EECCCCCCCCCCCCE	45.02	17330950
1187	Phosphorylation	RSLEDNETEIKVSRD CCCCCCCCEEEEEHH	49.63	28132839
1192	Phosphorylation	NETEIKVSRDTWNTK CCCEEEEEHHCCCCC	21.31	30377154
1387	Phosphorylation	SLYGLKQSGANWYET HHHCCHHCCCCHHHH	37.98	19779198
1392	Phosphorylation	KQSGANWYETIKSYL HHCCCCHHHHHHHHH	11.73	19779198
1480	Phosphorylation	IKYQRGKYMKLGMEN EEEECCCCCCCCCCC	11.42	19779198
1508	Phosphorylation	NPKGRKLSAPGQPGL CCCCCCCCCCCCCCE	35.14	28889911
1738	Phosphorylation	KNIADVMTKPLPIKT CCHHHHHCCCCCCCC	29.38	20377248

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of YL11B_YEAST !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of YL11B_YEAST !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of YL11B_YEAST !!

Protein-Protein Interaction

Oops, there are no PPI records of YL11B_YEAST !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.

Related Literatures of Post-Translational Modification

Acetylation

"Quantitative phosphoproteomics applied to the yeast pheromonesignaling pathway.";
Gruhler A., Olsen J.V., Mohammed S., Mortensen P., Faergeman N.J.,Mann M., Jensen O.N.;
Mol. Cell. Proteomics 4:310-327(2005).
Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT MET-1, PHOSPHORYLATION [LARGESCALE ANALYSIS] AT SER-13, AND MASS SPECTROMETRY.
PubMed: 15665377

Phosphorylation

"Quantitative phosphoproteomics applied to the yeast pheromonesignaling pathway.";
Gruhler A., Olsen J.V., Mohammed S., Mortensen P., Faergeman N.J.,Mann M., Jensen O.N.;
Mol. Cell. Proteomics 4:310-327(2005).
Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT MET-1, PHOSPHORYLATION [LARGESCALE ANALYSIS] AT SER-13, AND MASS SPECTROMETRY.
PubMed: 15665377