EMP47_YEAST - dbPTM
EMP47_YEAST - PTM Information in dbPTM
Basic Information of Protein
UniProt ID EMP47_YEAST
UniProt AC P43555
Protein Name Protein EMP47
Gene Name EMP47
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length 445
Subcellular Localization Golgi apparatus membrane
Single-pass type I membrane protein. Endoplasmic reticulum membrane
Single-pass type I membrane protein.
Protein Description Involved in the secretion of glycoproteins and in nucleus architecture and gene silencing. Required for the endoplasmic reticulum exit of EMP46..
Protein Sequence MMMLITMKSTVLLSVFTVLATWAGLLEAHPLGDTSDASKLSSDYSLPDLINARKVPNNWQTGEQASLEEGRIVLTSKQNSKGSLWLKQGFDLKDSFTMEWTFRSVGYSGQTDGGISFWFVQDSNVPRDKQLYNGPVNYDGLQLLVDNNGPLGPTLRGQLNDGQKPVDKTKIYDQSFASCLMGYQDSSVPSTIRVTYDLEDDNLLKVQVDNKVCFQTRKVRFPSGSYRIGVTAQNGAVNNNAESFEIFKMQFFNGVIEDSLIPNVNAMGQPKLITKYIDQQTGKEKLIEKTAFDADKDKITNYELYKKLDRVEGKILANDINALETKLNDVIKVQQELLSFMTTITKQLSSKPPANNEKGTSTDDAIAEDKENFKDFLSINQKLEKVLVEQEKYREATKRHGQDGPQVDEIARKLMIWLLPLIFIMLVMAYYTFRIRQEIIKTKLL
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
87AcetylationSKGSLWLKQGFDLKD
CCCCEEEEECCCCCC		36.4724489116
275AcetylationGQPKLITKYIDQQTG
CCCCHHHHHHHHHCC		32.9624489116
296AcetylationKTAFDADKDKITNYE
HHCCCCCHHHCCCHH		63.7424489116
2982-HydroxyisobutyrylationAFDADKDKITNYELY
CCCCCHHHCCCHHHH		58.11-
298AcetylationAFDADKDKITNYELY
CCCCCHHHCCCHHHH		58.1124489116
306SuccinylationITNYELYKKLDRVEG
CCCHHHHHHHHHHCC		60.5323954790
374AcetylationAEDKENFKDFLSINQ
HHCHHHHHHHHHHHH		60.1824489116
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of EMP47_YEAST !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of EMP47_YEAST !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of EMP47_YEAST !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
COPG_YEASTSEC21physical
12134087
SEC23_YEASTSEC23physical
12134087
COPA_YEASTCOP1physical
12134087
COPA_YEASTCOP1physical
14699056
EMP46_YEASTEMP46genetic
12134087
ERV41_YEASTERV41physical
18467557
RBD2_YEASTRBD2physical
18467557
COT1_YEASTCOT1physical
18467557
COPD_YEASTRET2physical
18467557
ATG27_YEASTATG27physical
18467557
ERV29_YEASTERV29physical
18467557
TMEDA_YEASTERV25physical
18467557
VPS68_YEASTVPS68physical
18467557
MDM10_YEASTMDM10physical
16093310
MKAR_YEASTIFA38physical
16093310
ELO2_YEASTELO2physical
16093310
VAM7_YEASTVAM7physical
16093310
YET1_YEASTYET1physical
16093310
SRPB_YEASTSRP102physical
16093310
EMP46_YEASTEMP46physical
16093310
ELO3_YEASTELO3physical
16093310
SULX_YEASTYPR003Cphysical
16093310
EMP47_YEASTEMP47physical
16093310
HSP72_YEASTSSA2physical
22940862
HSP71_YEASTSSA1physical
22940862
G3P3_YEASTTDH3physical
22940862
DED1_YEASTDED1physical
22940862
EMP47_YEASTEMP47physical
26447473
GAS1_YEASTGAS1genetic
26650540
MNN11_YEASTMNN11genetic
26650540
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of EMP47_YEAST

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Related Literatures of Post-Translational Modification

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