| UniProt ID | INM2_YEAST | |
|---|---|---|
| UniProt AC | Q05533 | |
| Protein Name | Inositol monophosphatase 2 | |
| Gene Name | INM2 | |
| Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast). | |
| Sequence Length | 292 | |
| Subcellular Localization | ||
| Protein Description | Responsible for the provision of inositol required for synthesis of phosphatidylinositol and polyphosphoinositides and involved in the inositol cycle of calcium signaling.. | |
| Protein Sequence | MVLTRQVLEEVENTFIELLRSKIGPLVKSHAGTNFCSYDDKANGVDLVTALDKQIESIIKENLTAKYPSFKFIGEETYVKGVTKITNGPTFIVDPIDGTTNFIHGYPYSCTSLGLAEMGKPVVGVVFNPHLNQLFHASKGNGAFLNDQEIKVSKRPLILQKSLIALEGGSERTEGSQGNFDKKMNTYKNLLSESGAFVHGFRSAGSAAMNICYVASGMLDAYWEGGCWAWDVCAGWCILEEAGGIMVGGNCGEWNIPLDRRCYLAIRGGCESMEQKRFAESFWPHVAGELEY | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 64 | Phosphorylation | SIIKENLTAKYPSFK HHHHHCCCCCCCCCE | 32.46 | 30377154 | |
| 67 | Phosphorylation | KENLTAKYPSFKFIG HHCCCCCCCCCEEEC | 11.14 | 30377154 | |
| 77 | Phosphorylation | FKFIGEETYVKGVTK CEEECCEEEECCEEE | 29.34 | 28889911 | |
| 161 | Acetylation | KRPLILQKSLIALEG CCCCHHHEEEEEECC | 43.73 | 22865919 | |
| 170 | Phosphorylation | LIALEGGSERTEGSQ EEEECCCCCCCCCCC | 34.46 | 30377154 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of INM2_YEAST !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of INM2_YEAST !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of INM2_YEAST !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
| PP2C4_YEAST | PTC4 | genetic | 19269370 | |
| VHS1_YEAST | VHS1 | genetic | 19269370 | |
| CWC26_YEAST | BUD13 | genetic | 19269370 | |
| VID30_YEAST | VID30 | genetic | 19269370 | |
| MDM10_YEAST | MDM10 | genetic | 20093466 | |
| AK_YEAST | HOM3 | genetic | 20093466 | |
| BLM10_YEAST | BLM10 | genetic | 20093466 | |
| THI73_YEAST | THI73 | genetic | 20093466 | |
| MAS5_YEAST | YDJ1 | genetic | 20093466 | |
| OYE3_YEAST | OYE3 | genetic | 20093466 | |
| FLC2_YEAST | FLC2 | genetic | 27708008 | |
| GPI7_YEAST | LAS21 | genetic | 27708008 | |
| GEM1_YEAST | GEM1 | genetic | 27708008 | |
| ETR1_YEAST | ETR1 | genetic | 27708008 | |
| RL13A_YEAST | RPL13A | genetic | 27708008 | |
| MAF1_YEAST | MAF1 | genetic | 27708008 | |
| BLM10_YEAST | BLM10 | genetic | 27708008 | |
| SIP2_YEAST | SIP2 | genetic | 27708008 | |
| GSH1_YEAST | GSH1 | genetic | 27708008 | |
| NKP2_YEAST | NKP2 | genetic | 27708008 | |
| CTF18_YEAST | CTF18 | genetic | 27708008 | |
| MAS5_YEAST | YDJ1 | genetic | 27708008 | |
| SUCA_YEAST | LSC1 | genetic | 27708008 | |
| FABD_YEAST | MCT1 | genetic | 27708008 | |
| OPY2_YEAST | OPY2 | genetic | 27708008 |
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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