INM2_YEAST - dbPTM
INM2_YEAST - PTM Information in dbPTM
Basic Information of Protein
UniProt ID INM2_YEAST
UniProt AC Q05533
Protein Name Inositol monophosphatase 2
Gene Name INM2
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length 292
Subcellular Localization
Protein Description Responsible for the provision of inositol required for synthesis of phosphatidylinositol and polyphosphoinositides and involved in the inositol cycle of calcium signaling..
Protein Sequence MVLTRQVLEEVENTFIELLRSKIGPLVKSHAGTNFCSYDDKANGVDLVTALDKQIESIIKENLTAKYPSFKFIGEETYVKGVTKITNGPTFIVDPIDGTTNFIHGYPYSCTSLGLAEMGKPVVGVVFNPHLNQLFHASKGNGAFLNDQEIKVSKRPLILQKSLIALEGGSERTEGSQGNFDKKMNTYKNLLSESGAFVHGFRSAGSAAMNICYVASGMLDAYWEGGCWAWDVCAGWCILEEAGGIMVGGNCGEWNIPLDRRCYLAIRGGCESMEQKRFAESFWPHVAGELEY
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure
ASA (%) Reference Orthologous
Protein Cluster
64PhosphorylationSIIKENLTAKYPSFK
HHHHHCCCCCCCCCE
32.4630377154
67PhosphorylationKENLTAKYPSFKFIG
HHCCCCCCCCCEEEC
11.1430377154
77PhosphorylationFKFIGEETYVKGVTK
CEEECCEEEECCEEE
29.3428889911
161AcetylationKRPLILQKSLIALEG
CCCCHHHEEEEEECC
43.7322865919
170PhosphorylationLIALEGGSERTEGSQ
EEEECCCCCCCCCCC
34.4630377154

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of INM2_YEAST !!

Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of INM2_YEAST !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10)
Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of INM2_YEAST !!

Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
PP2C4_YEASTPTC4genetic
19269370
VHS1_YEASTVHS1genetic
19269370
CWC26_YEASTBUD13genetic
19269370
VID30_YEASTVID30genetic
19269370
MDM10_YEASTMDM10genetic
20093466
AK_YEASTHOM3genetic
20093466
BLM10_YEASTBLM10genetic
20093466
THI73_YEASTTHI73genetic
20093466
MAS5_YEASTYDJ1genetic
20093466
OYE3_YEASTOYE3genetic
20093466
FLC2_YEASTFLC2genetic
27708008
GPI7_YEASTLAS21genetic
27708008
GEM1_YEASTGEM1genetic
27708008
ETR1_YEASTETR1genetic
27708008
RL13A_YEASTRPL13Agenetic
27708008
MAF1_YEASTMAF1genetic
27708008
BLM10_YEASTBLM10genetic
27708008
SIP2_YEASTSIP2genetic
27708008
GSH1_YEASTGSH1genetic
27708008
NKP2_YEASTNKP2genetic
27708008
CTF18_YEASTCTF18genetic
27708008
MAS5_YEASTYDJ1genetic
27708008
SUCA_YEASTLSC1genetic
27708008
FABD_YEASTMCT1genetic
27708008
OPY2_YEASTOPY2genetic
27708008

Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of INM2_YEAST

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Related Literatures of Post-Translational Modification

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