| UniProt ID | SDP1_YEAST | |
|---|---|---|
| UniProt AC | P40479 | |
| Protein Name | Dual-specificity protein phosphatase SDP1 | |
| Gene Name | SDP1 | |
| Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast). | |
| Sequence Length | 209 | |
| Subcellular Localization | ||
| Protein Description | Mediates dephosphorylation of MAPK substrates such as SLT2, acquiring enhanced catalytic activity under oxidative conditions.. | |
| Protein Sequence | MNIYTSPTRTPNIAPKSGQRPSLPMLATDERSTDKESPNEDREFVPCSSLDVRRIYPKGPLLVLPEKIYLYSEPTVKELLPFDVVINVAEEANDLRMQVPAVEYHHYRWEHDSQIALDLPSLTSIIHAATTKREKILIHCQCGLSRSATLIIAYIMKYHNLSLRHSYDLLKSRADKINPSIGLIFQLMEWEVALNAKTNVQANSYRKVP | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 4 | Phosphorylation | ----MNIYTSPTRTP ----CCCCCCCCCCC | 9.00 | 29650682 | |
| 5 | Phosphorylation | ---MNIYTSPTRTPN ---CCCCCCCCCCCC | 25.16 | 28152593 | |
| 6 | Phosphorylation | --MNIYTSPTRTPNI --CCCCCCCCCCCCC | 13.80 | 28152593 | |
| 8 | Phosphorylation | MNIYTSPTRTPNIAP CCCCCCCCCCCCCCC | 47.12 | 28152593 | |
| 10 | Phosphorylation | IYTSPTRTPNIAPKS CCCCCCCCCCCCCCC | 24.14 | 28152593 | |
| 22 | Phosphorylation | PKSGQRPSLPMLATD CCCCCCCCCCEEECC | 47.49 | 19779198 | |
| 37 | Phosphorylation | ERSTDKESPNEDREF CCCCCCCCCCCCCCC | 38.47 | 17330950 | |
| 72 | Phosphorylation | PEKIYLYSEPTVKEL CCEEEEECCCCHHHH | 34.21 | 28889911 | |
| 121 | Phosphorylation | QIALDLPSLTSIIHA EEEECHHHHHHHHHH | 52.13 | 27017623 | |
| 123 | Phosphorylation | ALDLPSLTSIIHAAT EECHHHHHHHHHHHC | 23.40 | 27017623 | |
| 124 | Phosphorylation | LDLPSLTSIIHAATT ECHHHHHHHHHHHCC | 25.49 | 27017623 | |
| 130 | Phosphorylation | TSIIHAATTKREKIL HHHHHHHCCCCCHHE | 33.36 | 27017623 | |
| 131 | Phosphorylation | SIIHAATTKREKILI HHHHHHCCCCCHHEE | 24.31 | 27017623 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of SDP1_YEAST !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of SDP1_YEAST !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of SDP1_YEAST !! | ||||||
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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