ITR2_YEAST - dbPTM
ITR2_YEAST - PTM Information in dbPTM
Basic Information of Protein
UniProt ID ITR2_YEAST
UniProt AC P30606
Protein Name Myo-inositol transporter 2
Gene Name ITR2
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length 609
Subcellular Localization Cell membrane
Multi-pass membrane protein .
Protein Description Minor transporter for myo-inositol..
Protein Sequence MKNSTAASSRWTKSRLSHFFPSYTNSSGMGAASTDQSSTQGEELHHRKHCEEDNDGQKPKKSPVSTSTMQIKSRQDEDEDDGRIVIKPVNDEDDTSVIITFNQSISPFIITLTFVASISGFMFGYDTGYISSALISINRDLDNKVLTYGEKELITAATSLGALITSVGAGTAADVFGRRPCLMFSNLMFLIGAILQITAHKFWQMAAGRLIMGFGVGIGSLISPLFISEIAPKMIRGRLTVINSLWLTGGQLIAYGCGAGLNHVKNGWRILVGLSLIPTVLQFSFFCFLPDTPRYYVMKGDLKRAKMVLKRSYVNTEDEIIDQKVEELSSLNQSIPGKNPITKFWNMVKELHTVPSNFRALIIGCGLQAIQQFTGWNSLMYFSGTIFETVGFKNSSAVSIIVSGTNFVFTLIAFFCIDKIGRRYILLIGLPGMTVALVICAIAFHFLGIKFNGADAVVASDGFSSWGIVIIVFIIVYAAFYALGIGTVPWQQSELFPQNVRGVGTSYATATNWAGSLVIASTFLTMLQNITPTGTFSFFAGVACLSTIFCYFCYPELSGLELEEVQTILKDGFNIKASKALAKKRKQQVAEGAAHHKLKFEPTQEIVES
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
26PhosphorylationFFPSYTNSSGMGAAS
HCCCCCCCCCCCCCC		22.0719779198
33PhosphorylationSSGMGAASTDQSSTQ
CCCCCCCCCCCCCCC		31.7921440633
34PhosphorylationSGMGAASTDQSSTQG
CCCCCCCCCCCCCCC		33.0728889911
37PhosphorylationGAASTDQSSTQGEEL
CCCCCCCCCCCCCCH		37.8628889911
38PhosphorylationAASTDQSSTQGEELH
CCCCCCCCCCCCCHH		21.0828889911
39PhosphorylationASTDQSSTQGEELHH
CCCCCCCCCCCCHHC		45.9328889911
62PhosphorylationDGQKPKKSPVSTSTM
CCCCCCCCCCCCCEE		36.3419779198
394N-linked_GlycosylationFETVGFKNSSAVSII
EEECCCCCCCEEEEE		38.65-
597UbiquitinationAEGAAHHKLKFEPTQ
HHHHHCCCCCCCCCH		43.4322817900
599UbiquitinationGAAHHKLKFEPTQEI
HHHCCCCCCCCCHHH		53.1124961812
603PhosphorylationHKLKFEPTQEIVES-
CCCCCCCCHHHHCC-		31.4725704821
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of ITR2_YEAST !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of ITR2_YEAST !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of ITR2_YEAST !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
ITR1_YEASTITR1genetic
18408719
PEX6_YEASTPEX6genetic
20526336
SWA2_YEASTSWA2genetic
20526336
SCH9_YEASTSCH9genetic
20526336
ADK_YEASTADO1genetic
21623372
ARGJ_YEASTARG7genetic
21623372
CBS_YEASTCYS4genetic
21623372
SERB_YEASTSER2genetic
21623372
DCOR_YEASTSPE1genetic
21623372
6PGD1_YEASTGND1genetic
21623372
EFM7_YEASTNNT1genetic
21623372
ACON2_YEASTACO2genetic
21623372
PYR1_YEASTURA2genetic
21623372
FOLE_YEASTMET7genetic
21623372
KAD2_YEASTADK1genetic
21623372
SAC1_YEASTSAC1genetic
27708008
ENV10_YEASTENV10genetic
27708008
RS3A2_YEASTRPS1Bgenetic
27708008
RL21B_YEASTRPL21Bgenetic
27708008
VPS8_YEASTVPS8genetic
27708008
ITR1_YEASTITR1genetic
27708008
IES5_YEASTIES5genetic
27708008
IES1_YEASTIES1genetic
27708008
PHB2_YEASTPHB2genetic
27708008
RS27B_YEASTRPS27Bgenetic
27708008
SKY1_YEASTSKY1genetic
27708008
FUMH_YEASTFUM1genetic
27708008
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of ITR2_YEAST

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Related Literatures of Post-Translational Modification

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