IRC5_YEAST - dbPTM
IRC5_YEAST - PTM Information in dbPTM
Basic Information of Protein
UniProt ID IRC5_YEAST
UniProt AC P43610
Protein Name Uncharacterized ATP-dependent helicase IRC5
Gene Name IRC5
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length 853
Subcellular Localization Nucleus .
Protein Description Is probably involved in a pathway contributing to genomic integrity..
Protein Sequence MSRCSNAALMTVVEDAVGARVAARTRNMSNGVNYREKEVNDLTADISDSDSDLDSEDNKHGKGDNDTAPIWLQDDVHSDEDIQLDSEDDSDTEAVQAQVVDKLAKDTKSEQKSLDDELSEMDTKTVSLKLKKLNEFVRQSQVYSSIIADTLLHRSNEVANANTKDNSNSDDEEHSSKKRKTKKKSITDFFKKQKKNEDTTTQNGAPDDAAIKQPRLLKNCILKPYQLEGLNWLITLYENGLNGILADEMGLGKTVQSIALLAFIYEMDTKGPFLVTAPLSTLDNWMNEFAKFAPDLPVLKYYGTNGYKERSAKLKNFFKQHGGTGIVITSYEIILRDTDLIMSQNWKFLIVDEGHRLKNINCRLIKELKKINTSNRLLLTGTPLQNNLAELWSLLNFIMPDIFADFEIFNKWFDFDSLNLGSGSNSEALNKLINDELQKNLISNLHTILKPFLLRRLKKVVLANILPPKREYIINCPMTSAQEKFYKAGLNGKLKKTMFKELIKDFFTLNDEYIGHVSNRSIRDFINYKLSGNETSNTDNKINPTLLQMDKLYKKNLQMEISNKKLQNMMMQLRQIIDSTFLFYFPYLHPEDLTLETLLKTSGKLQILQKLIPPLISEGHKVLIYSQFVNMLDLIEDWCDLNSFATFRIDGSVNNETRKDQLEKFNSSKDKHNIFLLSTRAAGLGINLVGADTVVLFDSDWNPQVDLQAMDRCHRIGQESPVIVYRLCCDNTIEHVILTRAANKRNLERMVIQMGKFNNLKKLALNEGSFLKANKAGVNVTNKDLVQELSMLLMSDESNIGFENGGQKENKATEGQLTDKEVEELTNRSLEAYKANRVVDLPHVKLFETTSGL
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
11PhosphorylationCSNAALMTVVEDAVG
CCHHHHHHHHHHHHH		23.4228889911
47PhosphorylationNDLTADISDSDSDLD
HHHCCCCCCCCCCCC		31.4521551504
49PhosphorylationLTADISDSDSDLDSE
HCCCCCCCCCCCCCC		32.0221551504
51PhosphorylationADISDSDSDLDSEDN
CCCCCCCCCCCCCCC		43.9821551504
167PhosphorylationNANTKDNSNSDDEEH
CCCCCCCCCCCCCHH		48.0923749301
169PhosphorylationNTKDNSNSDDEEHSS
CCCCCCCCCCCHHHH		46.3827214570
175PhosphorylationNSDDEEHSSKKRKTK
CCCCCHHHHHHHHHH		47.3224603354
176PhosphorylationSDDEEHSSKKRKTKK
CCCCHHHHHHHHHHH		44.0726447709
185PhosphorylationKRKTKKKSITDFFKK
HHHHHHHHHHHHHHH		39.3321551504
212UbiquitinationAPDDAAIKQPRLLKN
CCCHHHHCCHHHHHH		49.9123749301
343PhosphorylationRDTDLIMSQNWKFLI
CCCCHHHCCCCEEEE		17.2321440633
450UbiquitinationSNLHTILKPFLLRRL
HHHHHHHHHHHHHHH		29.8523749301
541AcetylationETSNTDNKINPTLLQ
CCCCCCCCCCHHHHH		46.8224489116
551UbiquitinationPTLLQMDKLYKKNLQ
HHHHHHHHHHHHHCH		48.6623749301
769PhosphorylationKLALNEGSFLKANKA
HHHHCCCCHHHHHCC		22.6430377154
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of IRC5_YEAST !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of IRC5_YEAST !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of IRC5_YEAST !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
RSC8_YEASTRSC8genetic
15870268
BMH1_YEASTBMH1genetic
17314980
SRB8_YEASTSRB8genetic
17314980
RAD51_YEASTRAD51genetic
17314980
CDC10_YEASTCDC10genetic
17314980
RSC6_YEASTRSC6genetic
17314980
DEP1_YEASTDEP1genetic
17314980
MMS4_YEASTMMS4genetic
20093466
SSD1_YEASTSSD1genetic
20093466
RAD51_YEASTRAD51genetic
20093466
RAD54_YEASTRAD54genetic
20093466
DOA1_YEASTDOA1genetic
20093466
MMS22_YEASTMMS22genetic
20093466
MRE11_YEASTMRE11genetic
20093466
OCA1_YEASTOCA1genetic
20093466
YP089_YEASTYPR089Wgenetic
20093466
MMS1_YEASTMMS1genetic
20093466
GPR1_YEASTGPR1genetic
27708008
RV167_YEASTRVS167genetic
27708008
CP56_YEASTDIT2genetic
27708008
RAD54_YEASTRAD54genetic
27708008
RAD52_YEASTRAD52genetic
27708008
GBLP_YEASTASC1genetic
27708008
MRE11_YEASTMRE11genetic
27708008
YP089_YEASTYPR089Wgenetic
27708008
MRC1_YEASTMRC1genetic
28383696
CTF18_YEASTCTF18genetic
28383696
CTF4_YEASTCTF4genetic
28383696
CSM3_YEASTCSM3genetic
28383696
SCC1_YEASTMCD1physical
28383696
SCC2_YEASTSCC2genetic
28383696
CHL1_YEASTCHL1genetic
28383696
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of IRC5_YEAST

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Related Literatures of Post-Translational Modification

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