| UniProt ID | TAF14_YEAST | |
|---|---|---|
| UniProt AC | P35189 | |
| Protein Name | Transcription initiation factor TFIID subunit 14 | |
| Gene Name | TAF14 | |
| Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast). | |
| Sequence Length | 244 | |
| Subcellular Localization | Nucleus. | |
| Protein Description | Functions as a component of the DNA-binding general transcription factor complex TFIID, the RNA polymerase II associated general transcription factor complex TFIIF, and the chromatin-remodeling complex SWI/SNF. [PubMed: 10788514] | |
| Protein Sequence | MVATVKRTIRIKTQQHILPEVPPVENFPVRQWSIEIVLLDDEGKEIPATIFDKVIYHLHPTFANPNRTFTDPPFRIEEQGWGGFPLDISVFLLEKAGERKIPHDLNFLQESYEVEHVIQIPLNKPLLTEELAKSGSTEETTANTGTIGKRRTTTNTTAEPKAKRAKTGSASTVKGSVDLEKLAFGLTKLNEDDLVGVVQMVTDNKTPEMNVTNNVEEGEFIIDLYSLPEGLLKSLWDYVKKNTE | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 12 | Ubiquitination | VKRTIRIKTQQHILP EEEEEEEEECCCCCC | 30.36 | 17644757 | |
| 49 | Phosphorylation | EGKEIPATIFDKVIY CCCCCCCCHHCCHHH | 19.47 | 27017623 | |
| 134 | Phosphorylation | LTEELAKSGSTEETT CCHHHHHCCCCCEEE | 32.16 | 22369663 | |
| 136 | Phosphorylation | EELAKSGSTEETTAN HHHHHCCCCCEEECC | 39.47 | 22369663 | |
| 137 | Phosphorylation | ELAKSGSTEETTANT HHHHCCCCCEEECCC | 41.17 | 22369663 | |
| 140 | Phosphorylation | KSGSTEETTANTGTI HCCCCCEEECCCCCC | 25.61 | 22369663 | |
| 141 | Phosphorylation | SGSTEETTANTGTIG CCCCCEEECCCCCCC | 22.61 | 23749301 | |
| 144 | Phosphorylation | TEETTANTGTIGKRR CCEEECCCCCCCCCE | 32.98 | 22369663 | |
| 146 | Phosphorylation | ETTANTGTIGKRRTT EEECCCCCCCCCEEC | 25.23 | 22369663 | |
| 149 | Acetylation | ANTGTIGKRRTTTNT CCCCCCCCCEECCCC | 34.55 | 25381059 | |
| 149 | Ubiquitination | ANTGTIGKRRTTTNT CCCCCCCCCEECCCC | 34.55 | 23749301 | |
| 152 | Phosphorylation | GTIGKRRTTTNTTAE CCCCCCEECCCCCCC | 41.84 | 30377154 | |
| 153 | Phosphorylation | TIGKRRTTTNTTAEP CCCCCEECCCCCCCC | 19.08 | 23749301 | |
| 154 | Phosphorylation | IGKRRTTTNTTAEPK CCCCEECCCCCCCCC | 29.92 | 27214570 | |
| 161 | Acetylation | TNTTAEPKAKRAKTG CCCCCCCCHHHCCCC | 59.03 | 25381059 | |
| 167 | Phosphorylation | PKAKRAKTGSASTVK CCHHHCCCCCCCCCC | 35.07 | 28889911 | |
| 169 | Phosphorylation | AKRAKTGSASTVKGS HHHCCCCCCCCCCCC | 25.03 | 27214570 | |
| 171 | Phosphorylation | RAKTGSASTVKGSVD HCCCCCCCCCCCCCC | 35.12 | 30377154 | |
| 181 | Ubiquitination | KGSVDLEKLAFGLTK CCCCCHHHHHHCCCC | 53.03 | 23749301 | |
| 181 | Acetylation | KGSVDLEKLAFGLTK CCCCCHHHHHHCCCC | 53.03 | 24489116 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of TAF14_YEAST !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of TAF14_YEAST !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of TAF14_YEAST !! | ||||||
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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