MNT2_YEAST - dbPTM
MNT2_YEAST - PTM Information in dbPTM
Basic Information of Protein
UniProt ID MNT2_YEAST
UniProt AC P53059
Protein Name Alpha-1,3-mannosyltransferase MNT2
Gene Name MNT2
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length 558
Subcellular Localization Golgi apparatus membrane
Single-pass type II membrane protein .
Protein Description Mannosyltransferase involved in adding the 4th and 5th mannose residues of O-linked glycans..
Protein Sequence MRRKNRLFILVVLLGIVLVVYYSQLNSLDLVEPVQSSSSGNGGCWSYYEGLTPGWLNDFYDVNQITPNPAKDVIELVTRIKIFFNCLQQVDGHNIQRLRDIEKKLFPYINFEKLETDESAFWHTTTRWNGEVYHASMLEFDPKNHQFLRSKPINFDTGLSFWENWLHTVTQSGSKGIVISASDVQLNETIRLLKVLRFIKNDYPIQIVHNADLSQDSMKSIIKYARSLDTAEYPAQELWFLNVHSLLNPKYSKKFTTYSNKWLALTFSSFEIPILMDSDTVPFVSIEKFYELEEFQKTGVLFFKDRVISDDLFESSELKILREIVYGCIGLDLEDESKIHEQVEDPVVAQVLENMFIKKYKHHLESGLVILHKGKHLFSMLTSIALQFSPIAEYFHGDKDFFWLGELLSNNRFTFHPVDASNIGQLGNVVSKESTGEFYQICSVQLSHTDRDGSLLWLNGGLNICKKTSWEYDYEHRQRLNDMFQNADELREYYASPVKLEGIIIPDTSISGWINSGECFLFNYCTLFKEGEFGKLIKFKEDEKLRLSQIVDIWNKDI
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
187N-linked_GlycosylationSASDVQLNETIRLLK
ECHHCCHHHHHHHHH		27.55-
414PhosphorylationLLSNNRFTFHPVDAS
HHHCCCCEECEECHH		20.1429136822
421PhosphorylationTFHPVDASNIGQLGN
EECEECHHHCHHHCC		25.2329136822
431PhosphorylationGQLGNVVSKESTGEF
HHHCCEEECCCCCCE		26.8229136822
434PhosphorylationGNVVSKESTGEFYQI
CCEEECCCCCCEEEE		45.5129136822
435PhosphorylationNVVSKESTGEFYQIC
CEEECCCCCCEEEEE		41.6529136822
439PhosphorylationKESTGEFYQICSVQL
CCCCCCEEEEEEEEE		7.8329136822
443PhosphorylationGEFYQICSVQLSHTD
CCEEEEEEEEECEEC		17.9629136822
447PhosphorylationQICSVQLSHTDRDGS
EEEEEEECEECCCCC		13.7829136822
449PhosphorylationCSVQLSHTDRDGSLL
EEEEECEECCCCCEE		29.3829136822
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of MNT2_YEAST !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of MNT2_YEAST !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of MNT2_YEAST !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
DEP1_YEASTDEP1genetic
20093466
RTG3_YEASTRTG3genetic
20093466
NRG2_YEASTNRG2genetic
20093466
TPS1_YEASTTPS1genetic
20093466
MSB2_YEASTMSB2genetic
20093466
PSD10_YEASTNAS6genetic
20093466
AIM24_YEASTAIM24genetic
20093466
MPS1_YEASTMPS1genetic
27708008
PRP9_YEASTPRP9genetic
27708008
TCPZ_YEASTCCT6genetic
27708008
SWC4_YEASTSWC4genetic
27708008
MPPA_YEASTMAS2genetic
27708008
KTHY_YEASTCDC8genetic
27708008
OLA1_YEASTOLA1genetic
27708008
CCZ1_YEASTCCZ1genetic
27708008
THRC_YEASTTHR4genetic
27708008
OST4_YEASTOST4genetic
27708008
MSB2_YEASTMSB2genetic
27708008
PSD10_YEASTNAS6genetic
27708008
UBA4_YEASTUBA4genetic
27708008
GVP36_YEASTGVP36genetic
27708008
AIM24_YEASTAIM24genetic
27708008
VPS24_YEASTVPS24genetic
27708008
SST2_YEASTSST2genetic
27708008
PHO80_YEASTPHO80genetic
27708008
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of MNT2_YEAST

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Related Literatures of Post-Translational Modification

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