PSD10_YEAST - dbPTM
PSD10_YEAST - PTM Information in dbPTM
Basic Information of Protein
UniProt ID PSD10_YEAST
UniProt AC P50086
Protein Name Probable 26S proteasome regulatory subunit p28
Gene Name NAS6
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length 228
Subcellular Localization
Protein Description Acts as a chaperone during the assembly of the 26S proteasome, specifically of the 19S regulatory complex (RC) and appears to have an overlapping role with RPN14..
Protein Sequence MSNYPLHQACMENEFFKVQELLHSKPSLLLQKDQDGRIPLHWSVSFQAHEITSFLLSKMENVNLDDYPDDSGWTPFHIACSVGNLEVVKSLYDRPLKPDLNKITNQGVTCLHLAVGKKWFEVSQFLIENGASVRIKDKFNQIPLHRAASVGSLKLIELLCGLGKSAVNWQDKQGWTPLFHALAEGHGDAAVLLVEKYGAEYDLVDNKGAKAEDVALNEQVKKFFLNNV
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
2Phosphorylation------MSNYPLHQA
------CCCCHHHHH		45.1028889911
4Phosphorylation----MSNYPLHQACM
----CCCCHHHHHHH		10.4028889911
24PhosphorylationKVQELLHSKPSLLLQ
HHHHHHHCCCCEEEE		46.3528889911
25AcetylationVQELLHSKPSLLLQK
HHHHHHCCCCEEEEE		28.0724489116
136AcetylationNGASVRIKDKFNQIP
CCCEEEEECCCCCCC		44.2824489116
138AcetylationASVRIKDKFNQIPLH
CEEEEECCCCCCCCC		41.0124489116
149PhosphorylationIPLHRAASVGSLKLI
CCCCCCCCCHHHHHH		26.4821440633
152PhosphorylationHRAASVGSLKLIELL
CCCCCCHHHHHHHHH		21.8524961812
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of PSD10_YEAST !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of PSD10_YEAST !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of PSD10_YEAST !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
PRS6B_YEASTRPT3physical
11283351
RPN10_YEASTRPN10physical
11029046
PRS8_YEASTRPT6physical
11029046
PRS6B_YEASTRPT3physical
16554755
RPN1_YEASTRPN1physical
16554755
PRS7_YEASTRPT1physical
16554755
SSB2_YEASTSSB2physical
16554755
PRS6A_YEASTRPT5physical
16554755
RPN8_YEASTRPN8physical
16554755
RPN2_YEASTRPN2physical
16429126
RPN3_YEASTRPN3physical
16429126
RPN8_YEASTRPN8physical
16429126
RPN1_YEASTRPN1physical
16429126
RPN9_YEASTRPN9physical
16429126
PRS7_YEASTRPT1physical
16429126
PRS6B_YEASTRPT3physical
16429126
PRS6A_YEASTRPT5physical
16429126
PRS8_YEASTRPT6physical
16429126
PRS6B_YEASTRPT3physical
17329811
PRS6B_YEASTRPT3physical
17555716
PRS7_YEASTRPT1physical
19412159
RPN11_YEASTRPN11physical
19412159
RPN8_YEASTRPN8physical
19412159
RPN12_YEASTRPN12physical
19412159
RPN3_YEASTRPN3physical
19412159
RPN5_YEASTRPN5physical
19412159
RPN6_YEASTRPN6physical
19412159
RPN7_YEASTRPN7physical
19412159
RPN9_YEASTRPN9physical
19412159
RPN1_YEASTRPN1physical
19412159
RPN2_YEASTRPN2physical
19412159
RPN10_YEASTRPN10physical
19412159
RPN13_YEASTRPN13physical
19412159
PRS4_YEASTRPT2physical
19412159
PRS6B_YEASTRPT3physical
19412159
PRS10_YEASTRPT4physical
19412159
PRS6A_YEASTRPT5physical
19412159
PRS8_YEASTRPT6physical
19412159
EMI2_YEASTEMI2physical
19412159
RL30_YEASTRPL30physical
19412159
G3P3_YEASTTDH3physical
19412159
STE23_YEASTSTE23physical
19412159
RL9A_YEASTRPL9Aphysical
19412159
RL9B_YEASTRPL9Bphysical
19412159
RL15A_YEASTRPL15Aphysical
19412159
RL15B_YEASTRPL15Bphysical
19412159
RPN14_YEASTRPN14genetic
19412159
HSM3_YEASTHSM3genetic
19412159
PSMD9_YEASTNAS2genetic
19446322
PRS8_YEASTRPT6genetic
19446322
RPN1_YEASTRPN1physical
19446323
RPN2_YEASTRPN2physical
19446323
RPN3_YEASTRPN3physical
19446323
PRS7_YEASTRPT1physical
19446323
PRS4_YEASTRPT2physical
19446323
PRS6B_YEASTRPT3physical
19446323
PRS10_YEASTRPT4physical
19446323
PRS6A_YEASTRPT5physical
19446323
RPN6_YEASTRPN6physical
19446323
PRS8_YEASTRPT6physical
19446323
RPN5_YEASTRPN5physical
19446323
RPN7_YEASTRPN7physical
19446323
RPN9_YEASTRPN9physical
19446323
RPN8_YEASTRPN8physical
19446323
RPN10_YEASTRPN10physical
19446323
RPN11_YEASTRPN11physical
19446323
RPN12_YEASTRPN12physical
19446323
SEM1_YEASTSEM1physical
19446323
RPN13_YEASTRPN13physical
19446323
RPN14_YEASTRPN14genetic
19446323
PSMD9_YEASTNAS2genetic
19446323
RPN14_YEASTRPN14physical
19446323
PSMD9_YEASTNAS2physical
20471945
RPN14_YEASTRPN14genetic
21878651
ECM29_YEASTECM29genetic
23995839
DHOM_YEASTHOM6genetic
27708008
YAJ9_YEASTYAR029Wgenetic
27708008
PANB_YEASTECM31genetic
27708008
MRM2_YEASTMRM2genetic
27708008
SDS3_YEASTSDS3genetic
27708008
SGN1_YEASTSGN1genetic
27708008
RL14A_YEASTRPL14Agenetic
27708008
MGLL_YEASTYJU3genetic
27708008
DS1P2_YEASTYSR3genetic
27708008
UBI4P_YEASTUBI4genetic
27708008
ARK1_YEASTARK1genetic
27708008
SSB1_YEASTSSB1genetic
28322792
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of PSD10_YEAST

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Related Literatures of Post-Translational Modification

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