RL15B_YEAST - dbPTM
RL15B_YEAST - PTM Information in dbPTM
Basic Information of Protein
UniProt ID RL15B_YEAST
UniProt AC P54780
Protein Name 60S ribosomal protein L15-B {ECO:0000303|PubMed:9559554}
Gene Name RPL15B {ECO:0000303|PubMed:9559554}
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length 204
Subcellular Localization Cytoplasm .
Protein Description Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules. The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain. The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel..
Protein Sequence MGAYKYLEELERKKQSDVLRFLQRVRVWEYRQKNVIHRAARPTRPDKARRLGYKAKQGFVIYRVRVRRGNRKRPVPKGATYGKPTNQGVNELKYQRSLRATAEERVGRRAANLRVLNSYWVNQDSTYKYFEVILVDPQHKAIRRDARYNWICNPVHKHREARGLTATGKKSRGINKGHKFNNTKAGRRKTWKRQNTLSLWRYRK
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
5Ubiquitination---MGAYKYLEELER
---CCHHHHHHHHHH		42.7117644757
13UbiquitinationYLEELERKKQSDVLR
HHHHHHHHHHHHHHH		45.8717644757
14UbiquitinationLEELERKKQSDVLRF
HHHHHHHHHHHHHHH		62.3417644757
33UbiquitinationRVWEYRQKNVIHRAA
HHHHHHHCCHHHHHC		44.1522817900
54UbiquitinationKARRLGYKAKQGFVI
HHHHHCCEECCCEEE		47.5122817900
56UbiquitinationRRLGYKAKQGFVIYR
HHHCCEECCCEEEEE		46.9623749301
72UbiquitinationRVRRGNRKRPVPKGA
EEECCCCCCCCCCCC		66.1222817900
77UbiquitinationNRKRPVPKGATYGKP
CCCCCCCCCCCCCCC		62.5022817900
80PhosphorylationRPVPKGATYGKPTNQ
CCCCCCCCCCCCCCC		41.2821440633
81PhosphorylationPVPKGATYGKPTNQG
CCCCCCCCCCCCCCC		23.7128889911
83UbiquitinationPKGATYGKPTNQGVN
CCCCCCCCCCCCCHH		37.9523749301
85PhosphorylationGATYGKPTNQGVNEL
CCCCCCCCCCCHHHH		43.5921440633
93UbiquitinationNQGVNELKYQRSLRA
CCCHHHHHHHHHHHH		32.9123749301
118PhosphorylationANLRVLNSYWVNQDS
HCCEEEEEEEECCCC		19.0628152593
126PhosphorylationYWVNQDSTYKYFEVI
EEECCCCCCEEEEEE		32.1130377154
128UbiquitinationVNQDSTYKYFEVILV
ECCCCCCEEEEEEEE		43.4823749301
140UbiquitinationILVDPQHKAIRRDAR
EEECCCCHHHHHHHC		40.0223749301
157UbiquitinationWICNPVHKHREARGL
CCCCHHHHCHHHHCC		44.5917644757
170UbiquitinationGLTATGKKSRGINKG
CCCCCCCCCCCCCCC		46.8917644757
171PhosphorylationLTATGKKSRGINKGH
CCCCCCCCCCCCCCC		38.9419795423
176UbiquitinationKKSRGINKGHKFNNT
CCCCCCCCCCCCCCC		61.5417644757
179UbiquitinationRGINKGHKFNNTKAG
CCCCCCCCCCCCHHC		59.4622817900
184UbiquitinationGHKFNNTKAGRRKTW
CCCCCCCHHCCCCCH		51.4722817900
189UbiquitinationNTKAGRRKTWKRQNT
CCHHCCCCCHHHHCC		58.3322817900
192UbiquitinationAGRRKTWKRQNTLSL
HCCCCCHHHHCCHHH		49.7017644757
196PhosphorylationKTWKRQNTLSLWRYR
CCHHHHCCHHHEEEC		14.9123749301
198PhosphorylationWKRQNTLSLWRYRK-
HHHHCCHHHEEECC-		24.6917287358
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of RL15B_YEAST !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of RL15B_YEAST !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of RL15B_YEAST !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
RIM11_YEASTRIM11physical
18719252
SSZ1_YEASTSSZ1physical
19536198
SSB1_YEASTSSB1physical
19536198
HPC2_YEASTHPC2genetic
27708008
CHK1_YEASTCHK1genetic
27708008
DAL81_YEASTDAL81genetic
27708008
COQ2_YEASTCOQ2genetic
27708008
HMI1_YEASTHMI1genetic
27708008
PT127_YEASTPET127genetic
27708008
CDC37_YEASTCDC37genetic
27708008
SNU56_YEASTSNU56genetic
27708008
GPI11_YEASTGPI11genetic
27708008
RPB7_YEASTRPB7genetic
27708008
MED6_YEASTMED6genetic
27708008
SPC97_YEASTSPC97genetic
27708008
FNTA_YEASTRAM2genetic
27708008
ECM33_YEASTECM33genetic
27708008
ODPB_YEASTPDB1genetic
27708008
YB92_YEASTYBR242Wgenetic
27708008
YCY0_YEASTYCR090Cgenetic
27708008
RM01_YEASTMRPL1genetic
27708008
RPA14_YEASTRPA14genetic
27708008
GRH1_YEASTGRH1genetic
27708008
ODPA_YEASTPDA1genetic
27708008
PALF_YEASTRIM8genetic
27708008
ATC1_YEASTPMR1genetic
27708008
MSC7_YEASTMSC7genetic
27708008
HTD2_YEASTHTD2genetic
27708008
PTH_YEASTPTH1genetic
27708008
GSH1_YEASTGSH1genetic
27708008
COXM1_YEASTCMC1genetic
27708008
RL8B_YEASTRPL8Bgenetic
27708008
SWI6_YEASTSWI6genetic
27708008
ADY4_YEASTADY4genetic
27708008
COQ11_YEASTYLR290Cgenetic
27708008
SAP30_YEASTSAP30genetic
27708008
PET8_YEASTPET8genetic
27708008
ODP2_YEASTLAT1genetic
27708008
PFD4_YEASTGIM3genetic
27708008
MSO1_YEASTMSO1genetic
27708008
IZH2_YEASTIZH2genetic
27708008
SIN3_YEASTSIN3genetic
27708008
RLA2_YEASTRPP2Agenetic
27708008
GSHB_YEASTGSH2genetic
27708008
INO4_YEASTINO4genetic
27708008
SMF1_YEASTSMF1genetic
27708008
VPS68_YEASTVPS68genetic
27708008
RTC1_YEASTRTC1genetic
27708008
TYW4_YEASTPPM2genetic
27708008
RAD1_YEASTRAD1genetic
27708008
MTHR1_YEASTMET12genetic
27708008
NACB1_YEASTEGD1genetic
27708008
GGPPS_YEASTBTS1genetic
27708008
RBD2_YEASTRBD2genetic
27708008
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of RL15B_YEAST

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Related Literatures of Post-Translational Modification

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