PSMD9_YEAST - dbPTM
PSMD9_YEAST - PTM Information in dbPTM
Basic Information of Protein
UniProt ID PSMD9_YEAST
UniProt AC P40555
Protein Name Probable 26S proteasome regulatory subunit p27
Gene Name NAS2
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length 220
Subcellular Localization
Protein Description Acts as a chaperone during the assembly of the 26S proteasome, specifically of the base subcomplex of the 19S regulatory complex (RC). During the base subcomplex assembly is part of a NAS2:RPT4:RPT5 module; NAS2 is released during the further base assembly process..
Protein Sequence MEEEELSKLLANVKIDPSLTSRISQIDSFKLSELMVLKTDIETQLEAYFSVLEQQGIGMDSALVTPDGYPRSDVDVLQVTMIRKNVNMLKNDLNHLLQRSHVLLNQHFDNMNVKSNQDARRNNDDQAIQYTIPFAFISEVVPGSPSDKADIKVDDKLISIGNVHAANHSKLQNIQMVVMKNEDRPLPVLLLREGQILKTSLTPSRNWNGRGLLGCRIQEL
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
20PhosphorylationVKIDPSLTSRISQID
CCCCHHHHHHHHHCC		21.9427017623
24PhosphorylationPSLTSRISQIDSFKL
HHHHHHHHHCCCCCH		21.7027017623
30UbiquitinationISQIDSFKLSELMVL
HHHCCCCCHHEEEEE		55.8719722269
32PhosphorylationQIDSFKLSELMVLKT
HCCCCCHHEEEEECC		29.3127017623
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of PSMD9_YEAST !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of PSMD9_YEAST !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of PSMD9_YEAST !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
ACON_YEASTACO1physical
11805837
ADY1_YEASTPFS1physical
10688190
SKT5_YEASTSKT5physical
11489916
ADY1_YEASTPFS1physical
11489916
RPN4_YEASTRPN4physical
11489916
PRS6A_YEASTRPT5physical
11283351
ADY1_YEASTPFS1physical
18719252
RV161_YEASTRVS161genetic
18931302
PRS10_YEASTRPT4physical
19446322
PRS6A_YEASTRPT5physical
19446322
HSM3_YEASTHSM3genetic
19446322
PRS6B_YEASTRPT3physical
19446323
PRS10_YEASTRPT4physical
19446323
PRS6A_YEASTRPT5physical
19446323
RPN6_YEASTRPN6physical
19446323
PRS8_YEASTRPT6physical
19446323
HSM3_YEASTHSM3genetic
19446323
PRS4_YEASTRPT2physical
19446323
RPN3_YEASTRPN3genetic
19446323
PRS10_YEASTRPT4physical
15687504
PRS7_YEASTRPT1physical
15687504
PRS6B_YEASTRPT3physical
20471945
PRS8_YEASTRPT6physical
20471945
PSD10_YEASTNAS6physical
20471945
RPN14_YEASTRPN14physical
20471945
PRS6A_YEASTRPT5physical
20471945
PRS6A_YEASTRPT5physical
21878651
ECM29_YEASTECM29genetic
21878651
ECM29_YEASTECM29genetic
23995839
MOB2_YEASTMOB2genetic
27708008
STE50_YEASTSTE50genetic
27708008
VMA21_YEASTVMA21genetic
27708008
GTR2_YEASTGTR2genetic
27708008
KRR1_YEASTKRR1genetic
27708008
APC11_YEASTAPC11genetic
27708008
CDC53_YEASTCDC53genetic
27708008
NOP14_YEASTNOP14genetic
27708008
FCF1_YEASTFCF1genetic
27708008
SMD1_YEASTSMD1genetic
27708008
RPN1_YEASTRPN1genetic
27708008
ORC6_YEASTORC6genetic
27708008
KTHY_YEASTCDC8genetic
27708008
NSE1_YEASTNSE1genetic
27708008
DCP2_YEASTDCP2genetic
27708008
RIB2_YEASTRIB2genetic
27708008
PRS10_YEASTRPT4genetic
27708008
PSB5_YEASTPRE2genetic
27708008
BUR1_YEASTSGV1genetic
27708008
NTH1_YEASTNTG1genetic
27708008
ETR1_YEASTETR1genetic
27708008
SWC5_YEASTSWC5genetic
27708008
PP2C1_YEASTPTC1genetic
27708008
AAD4_YEASTAAD4genetic
27708008
ACL4_YEASTYDR161Wgenetic
27708008
H2A1_YEASTHTA1genetic
27708008
CEM1_YEASTCEM1genetic
27708008
ADH4_YEASTADH4genetic
27708008
CUL3_YEASTCUL3genetic
27708008
YG51_YEASTYGR237Cgenetic
27708008
TBP7_YEASTYTA7genetic
27708008
RL8A_YEASTRPL8Agenetic
27708008
SODM_YEASTSOD2genetic
27708008
HTD2_YEASTHTD2genetic
27708008
NCA3_YEASTNCA3genetic
27708008
DAS1_YEASTDAS1genetic
27708008
ITPA_YEASTHAM1genetic
27708008
IME1_YEASTIME1genetic
27708008
YJ90_YEASTYJR120Wgenetic
27708008
FABG_YEASTOAR1genetic
27708008
ZRT3_YEASTZRT3genetic
27708008
SAC1_YEASTSAC1genetic
27708008
MCH2_YEASTMCH2genetic
27708008
UTH1_YEASTUTH1genetic
27708008
YL032_YEASTYLL032Cgenetic
27708008
YL149_YEASTYLR149Cgenetic
27708008
LIPB_YEASTLIP2genetic
27708008
YL278_YEASTYLR278Cgenetic
27708008
NKP2_YEASTNKP2genetic
27708008
RL6B_YEASTRPL6Bgenetic
27708008
TRI1_YEASTTRI1genetic
27708008
PMS1_YEASTPMS1genetic
27708008
OCA1_YEASTOCA1genetic
27708008
ATG3_YEASTATG3genetic
27708008
BRE5_YEASTBRE5genetic
27708008
YAP4_YEASTCIN5genetic
27708008
CY1_YEASTCYT1genetic
27708008
LIPA_YEASTLIP5genetic
27708008
FABD_YEASTMCT1genetic
27708008
PMT3_YEASTPMT3genetic
27708008
HAT1_YEASTHAT1genetic
27708008
MRX11_YEASTYPL041Cgenetic
27708008
SUE1_YEASTSUE1genetic
27708008
VPS4_YEASTVPS4genetic
27708008
SSB1_YEASTSSB1genetic
28322792
PRS10_YEASTRPT4physical
24685148
PRS6A_YEASTRPT5physical
24685148
PRS6B_YEASTRPT3physical
24685148
PRS8_YEASTRPT6physical
24685148
RPN2_YEASTRPN2physical
24685148
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of PSMD9_YEAST

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Related Literatures of Post-Translational Modification

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