BUD17_YEAST - dbPTM
BUD17_YEAST - PTM Information in dbPTM
Basic Information of Protein
UniProt ID BUD17_YEAST
UniProt AC P53727
Protein Name Putative pyridoxal kinase BUD17
Gene Name BUD17
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length 317
Subcellular Localization Cytoplasm . Nucleus .
Protein Description Required for synthesis of pyridoxal-5-phosphate from vitamin B6 (By similarity). Important for bud site selection..
Protein Sequence MTSTLHTTKKVLSIQSHVIHGYVGNKAATFPLQYRGWDVDVLNTVQFSNHSGYAHFTGFKCSTEELVDIVEKGLIGSLRIKYDAVLSGYLPNVQALQKVAGIVGQLCEGSENVKWILDPVLGDNGRLYVDRECVAVYQDILQNFKIFLATPNQFEMELLVGMSIRTLDDAKQAFKLFHKKYPRVSRIVVTSLELSEFLSNDTYVVAGFDCSASEEIFFYEIPKINAKFSGSGDLISAMLTDSLLGDRRCTQLSLSASLGQVLWLVTSILQKTYDLNIAERGPQDSTIDIKDLKLIQCRDILKQDLIPSIGKPKTIKI
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure
ASA (%) Reference Orthologous
Protein Cluster
2Phosphorylation------MTSTLHTTK
------CCCCCHHCH
30.3422369663
3Phosphorylation-----MTSTLHTTKK
-----CCCCCHHCHH
27.8922369663
4Phosphorylation----MTSTLHTTKKV
----CCCCCHHCHHE
17.2522369663
7Phosphorylation-MTSTLHTTKKVLSI
-CCCCCHHCHHEHEE
43.3422369663
8PhosphorylationMTSTLHTTKKVLSIQ
CCCCCHHCHHEHEEE
20.3722369663
13PhosphorylationHTTKKVLSIQSHVIH
HHCHHEHEEECCEEC
22.9022369663
16PhosphorylationKKVLSIQSHVIHGYV
HHEHEEECCEECCCC
20.3222369663
22PhosphorylationQSHVIHGYVGNKAAT
ECCEECCCCCCCEEE
7.3322369663
290AcetylationQDSTIDIKDLKLIQC
CCCCCCHHHCCEEEE
53.9424489116

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of BUD17_YEAST !!

Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of BUD17_YEAST !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10)
Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of BUD17_YEAST !!

Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
BUD16_YEASTBUD16physical
18719252
HSP7F_YEASTSSE1physical
19536198
PP2C1_YEASTPTC1genetic
27708008
MTU1_YEASTSLM3genetic
27708008
S2538_YEASTYDL119Cgenetic
27708008
VMA21_YEASTVMA21genetic
27708008
PHB2_YEASTPHB2genetic
27708008
RS27B_YEASTRPS27Bgenetic
27708008
DAL81_YEASTDAL81genetic
27708008
FEN1_YEASTRAD27genetic
27708008
PCKA_YEASTPCK1genetic
27708008
CY1_YEASTCYT1genetic
27708008

Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of BUD17_YEAST

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Related Literatures of Post-Translational Modification

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