RMAR_YEAST - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: RMAR_YEAST
• UniProt AC: P02381
• Protein Name: Ribosomal protein VAR1, mitochondrial
• Gene Name: VAR1
• Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
• Sequence Length: 398
• Subcellular Localization: Mitochondrion . Mitoribosomes are tethered to the mitochondrial inner membrane and spatially aligned with the membrane insertion machinery through two distinct membrane contact sites, formed by the 21S rRNA expansion segment 96-ES1 and the inner memb
• Protein Description: Component of the mitochondrial ribosome (mitoribosome), a dedicated translation machinery responsible for the synthesis of mitochondrial genome-encoded proteins, including at least some of the essential transmembrane subunits of the mitochondrial respiratory chain. The mitoribosomes are attached to the mitochondrial inner membrane and translation products are cotranslationally integrated into the membrane. [PubMed: 25609543]
• Protein Sequence: MKLKLLNMILSMMNKTNNNNNIIINNTLDSLMNKKLLLKNMLLDMNNKKMNNMKRMLNNNNMNPAGANPVVHRIGPAGNINNKLQHLNNMNNWNTQIYNYNKNMEIMNTMNDKLINKLLYKMMTLKLNNMNINKIIMSKTINQHSLNKLNIKFYYYNNDINNNNNNNNNNYYMNMMNKLMNIMNNNMNNNLCNILSYYYKKKVTIEPIKLSYIYLNSDIFSKYISLNDMDKYNNGILTNYQRMLNNIMPKLNDHNISMNYINNINNINNNKYNNMINLLNNNNNINNNNNYNNNNNNYIGNINNIYNNMTIDNIPMDILMYKYLVGWSIKFKGRLSNNNGRTSTTNLLNGTFNNKKYLWSNINNNYKLNYIPSNHNLYNNSNINKNGKYNIKVKLNFI

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
11	Phosphorylation	KLLNMILSMMNKTNN HHHHHHHHHHHHCCC	12.69	28132839
39	Acetylation	MNKKLLLKNMLLDMN HCHHHHHHHHHHHCC	40.04	25381059
48	Acetylation	MLLDMNNKKMNNMKR HHHHCCHHHHHHHHH	48.68	25381059
370	Phosphorylation	NNNYKLNYIPSNHNL CCCEEEEECCCCCCC	25.33	29688323
373	Phosphorylation	YKLNYIPSNHNLYNN EEEEECCCCCCCCCC	40.96	29688323
378	Phosphorylation	IPSNHNLYNNSNINK CCCCCCCCCCCCCCC	20.02	29688323
381	Phosphorylation	NHNLYNNSNINKNGK CCCCCCCCCCCCCCC	35.13	29688323

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of RMAR_YEAST !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of RMAR_YEAST !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of RMAR_YEAST !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
SUV3_YEAST	SUV3	genetic	2698840

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.