dbPTM

OPY1_YEAST - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	OPY1_YEAST
UniProt AC	P38271
Protein Name	Protein OPY1
Gene Name	OPY1
Organism	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length	328
Subcellular Localization
Protein Description
Protein Sequence	MIAGATAPSSQHEILIASNLIKKPSTSQNKTPTAQSSSGNNGAADGAPQGYHHHHHHHRHLWWPRTTDHQYWCVLRKNQFAYYKTRDEREAISVIPRFDILNFKISELDGILTVYTPSKDLIFKFPRGQNEKVGMELMHNWKIALEKFLSSPSGNESVTTGSDYDEEEDDDDLIVVDEKAGPSSSKHSCSLTMDEQLSREDKEFYRMFDPRNAEHQVCSGILYTKVKKKKLFNRAKWQKFNVELTNTSFNLYSFKTGKLKKSIKLDKIIDCIELDNNSKMKNDDTNFALITFDERLSFKAANDQDMVDWIINFKSGILIRKKLKAENI

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
25	Phosphorylation	SNLIKKPSTSQNKTP ECCCCCCCCCCCCCC	49.96	27214570
31	Phosphorylation	PSTSQNKTPTAQSSS CCCCCCCCCCCCCCC	33.16	23749301
33	Phosphorylation	TSQNKTPTAQSSSGN CCCCCCCCCCCCCCC	42.43	23749301
124	Acetylation	PSKDLIFKFPRGQNE CCCCEEEECCCCCCC	47.68	24489116
151	Phosphorylation	ALEKFLSSPSGNESV HHHHHHCCCCCCCCC	25.82	25882841
159	Phosphorylation	PSGNESVTTGSDYDE CCCCCCCCCCCCCCC	34.42	27214570
162	Phosphorylation	NESVTTGSDYDEEED CCCCCCCCCCCCCCC	30.79	28889911
164	Phosphorylation	SVTTGSDYDEEEDDD CCCCCCCCCCCCCCC	27.27	21440633
183	Phosphorylation	VDEKAGPSSSKHSCS EECCCCCCCCCCEEE	46.45	23749301
184	Phosphorylation	DEKAGPSSSKHSCSL ECCCCCCCCCCEEEC	46.68	23749301
185	Phosphorylation	EKAGPSSSKHSCSLT CCCCCCCCCCEEECC	38.43	20377248
186	Ubiquitination	KAGPSSSKHSCSLTM CCCCCCCCCEEECCC	41.29	23749301
188	Phosphorylation	GPSSSKHSCSLTMDE CCCCCCCEEECCCCC	14.78	20377248
190	Phosphorylation	SSSKHSCSLTMDEQL CCCCCEEECCCCCHH	29.86	21440633
192	Phosphorylation	SKHSCSLTMDEQLSR CCCEEECCCCCHHCH	13.29	23749301
198	Phosphorylation	LTMDEQLSREDKEFY CCCCCHHCHHHHHHH	33.06	19823750

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of OPY1_YEAST !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of OPY1_YEAST !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of OPY1_YEAST !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
SLT2_YEAST	SLT2	genetic	19269370
SWD1_YEAST	SWD1	genetic	19269370
RXT2_YEAST	RXT2	genetic	19269370
STE50_YEAST	STE50	genetic	19269370
MNN10_YEAST	MNN10	genetic	19269370
BMH1_YEAST	BMH1	genetic	19269370
CSK2B_YEAST	CKB1	genetic	19269370
BCK1_YEAST	BCK1	genetic	19269370
MNN11_YEAST	MNN11	genetic	19269370
DOA1_YEAST	DOA1	genetic	19269370
H2AZ_YEAST	HTZ1	genetic	19269370
PLC1_YEAST	PLC1	genetic	19269370
SKI3_YEAST	SKI3	genetic	19269370
INP52_YEAST	INP52	genetic	22562153
INP51_YEAST	INP51	genetic	22562153
RV161_YEAST	RVS161	genetic	27708008
VPS41_YEAST	VPS41	genetic	27708008
ARO1_YEAST	ARO1	genetic	27708008
SAC3_YEAST	SAC3	genetic	27708008
NACB2_YEAST	BTT1	genetic	27708008
SUR2_YEAST	SUR2	genetic	27708008
RV167_YEAST	RVS167	genetic	27708008
SAC7_YEAST	SAC7	genetic	27708008
GTR2_YEAST	GTR2	genetic	27708008
MEH1_YEAST	MEH1	genetic	27708008
SOK2_YEAST	SOK2	genetic	27708008
NST1_YEAST	NST1	genetic	27708008
RTC1_YEAST	RTC1	genetic	27708008
2A5D_YEAST	RTS1	genetic	27708008
VAM10_YEAST	VAM10	genetic	27708008
FA81B_HUMAN	FAM81B	physical	27107014

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of OPY1_YEAST

Related Literatures of Post-Translational Modification