FA81B_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: FA81B_HUMAN
• UniProt AC: Q96LP2
• Protein Name: Protein FAM81B
• Gene Name: FAM81B
• Organism: Homo sapiens (Human).
• Sequence Length: 452
• Protein Sequence: MQLQFLGTLASSEKRKKSQRLFFKNIKSTKNKAGKASIMSSDTNVNKSASPTATAEEQPVEPDGPLPGSDNNQEKKVRLSPAKMSTKNSTDLVEYVDKSHAFLPIIPNTQRGQLEDRLNNQARTIAFLLEQAFRIKEDISACLQGTHGFRKEESLARKLLESHIQTITSIVKKLSQNIEILEDQIRARDQAATGTNFAVHEINIKHLQGVGDLRGRVARCDSSIVKLSGDIHLFRQEHRQIEKAIQEFVPALETLSKNLDMKVMQLLGKIETASPEQTSNLKMVQGDYRHEMNLLEFKFHSLSSNLYEEVENNKKWTENQFLKYRKDHLGHINECLKVLQEKLEKSENKMEEKLLQLSSKVENFINTQKQETQLSKVKHMENKLSKKMEQMEKQIWGELETMQNEYQSGFKSIHDSLSSLQQIQKTKMDLEKYKVQKDLKKLQRKIVELQEV

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
28	Phosphorylation	LFFKNIKSTKNKAGK HHHCHHHCCCCCCCC	40.60	29083192
29	Phosphorylation	FFKNIKSTKNKAGKA HHCHHHCCCCCCCCC	33.37	29083192
76	Ubiquitination	SDNNQEKKVRLSPAK CCCCCCCCEECCCCC	31.66	-
80	Phosphorylation	QEKKVRLSPAKMSTK CCCCEECCCCCCCCC	16.55	24719451
87	Ubiquitination	SPAKMSTKNSTDLVE CCCCCCCCCCCCHHH	41.41	-
89	Phosphorylation	AKMSTKNSTDLVEYV CCCCCCCCCCHHHHH	25.50	30622161
90	Phosphorylation	KMSTKNSTDLVEYVD CCCCCCCCCHHHHHC	42.62	30622161
99	Phosphorylation	LVEYVDKSHAFLPII HHHHHCCCCCCCEEC	18.65	-
162	Phosphorylation	LARKLLESHIQTITS HHHHHHHHHHHHHHH	26.34	-
168	Phosphorylation	ESHIQTITSIVKKLS HHHHHHHHHHHHHHH	18.78	27732954
169	Phosphorylation	SHIQTITSIVKKLSQ HHHHHHHHHHHHHHH	22.87	27732954
358	Phosphorylation	EEKLLQLSSKVENFI HHHHHHHHHHHHHHH	18.36	-
359	Phosphorylation	EKLLQLSSKVENFIN HHHHHHHHHHHHHHH	49.68	-
372	Phosphorylation	INTQKQETQLSKVKH HHHHHHHHHHHHHHH	32.11	-
385	Phosphorylation	KHMENKLSKKMEQME HHHHHHHHHHHHHHH	31.66	22985185
386	Acetylation	HMENKLSKKMEQMEK HHHHHHHHHHHHHHH	67.58	11921465
412	Phosphorylation	EYQSGFKSIHDSLSS HHHHCHHHHHHHHHH	23.93	30622161
416	Phosphorylation	GFKSIHDSLSSLQQI CHHHHHHHHHHHHHH	18.91	30622161
418	Phosphorylation	KSIHDSLSSLQQIQK HHHHHHHHHHHHHHH	32.71	30622161
419	Phosphorylation	SIHDSLSSLQQIQKT HHHHHHHHHHHHHHH	35.18	30622161

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of FA81B_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of FA81B_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of FA81B_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
PCNT_HUMAN	PCNT	physical	28514442
PCM1_HUMAN	PCM1	physical	28514442
CK5P2_HUMAN	CDK5RAP2	physical	28514442

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.