| UniProt ID | HIS8_YEAST | |
|---|---|---|
| UniProt AC | P07172 | |
| Protein Name | Histidinol-phosphate aminotransferase | |
| Gene Name | HIS5 | |
| Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast). | |
| Sequence Length | 385 | |
| Subcellular Localization | ||
| Protein Description | ||
| Protein Sequence | MVFDLKRIVRPKIYNLEPYRCARDDFTEGILLDANENAHGPTPVELSKTNLHRYPDPHQLEFKTAMTKYRNKTSSYANDPEVKPLTADNLCLGVGSDESIDAIIRACCVPGKEKILVLPPTYSMYSVCANINDIEVVQCPLTVSDGSFQMDTEAVLTILKNDSLIKLMFVTSPGNPTGAKIKTSLIEKVLQNWDNGLVVVDEAYVDFCGGSTAPLVTKYPNLVTLQTLSKSFGLAGIRLGMTYATAELARILNAMKAPYNISSLASEYALKAVQDSNLKKMEATSKIINEEKMRLLKELTALDYVDDQYVGGLDANFLLIRINGGDNVLAKKLYYQLATQSGVVVRFRGNELGCSGCLRITVGTHEENTHLIKYFKETLYKLANE | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 12 | Acetylation | LKRIVRPKIYNLEPY HHHCCCCCCCCCCCC | 47.46 | 24489116 | |
| 63 | Ubiquitination | DPHQLEFKTAMTKYR CHHHHHHHHHHHHHC | 26.46 | 22817900 | |
| 68 | Ubiquitination | EFKTAMTKYRNKTSS HHHHHHHHHCCCCCC | 29.18 | 22817900 | |
| 171 | Phosphorylation | LIKLMFVTSPGNPTG EEEEEEEECCCCCCC | 20.24 | 22369663 | |
| 172 | Phosphorylation | IKLMFVTSPGNPTGA EEEEEEECCCCCCCH | 26.05 | 22369663 | |
| 177 | Phosphorylation | VTSPGNPTGAKIKTS EECCCCCCCHHHHHH | 54.49 | 22369663 | |
| 230 | N6-(pyridoxal phosphate)lysine | VTLQTLSKSFGLAGI EEHHHHHHHCCCHHH | 53.57 | - | |
| 230 | Acetylation | VTLQTLSKSFGLAGI EEHHHHHHHCCCHHH | 53.57 | 24489116 | |
| 230 | Other | VTLQTLSKSFGLAGI EEHHHHHHHCCCHHH | 53.57 | - | |
| 292 | Ubiquitination | SKIINEEKMRLLKEL HHHCCHHHHHHHHHH | 24.12 | 23749301 | |
| 331 | Ubiquitination | GGDNVLAKKLYYQLA CCCCHHHHHHHHHHH | 38.87 | 23749301 | |
| 373 | Acetylation | EENTHLIKYFKETLY CCCHHHHHHHHHHHH | 51.50 | 22865919 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of HIS8_YEAST !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of HIS8_YEAST !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of HIS8_YEAST !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
Oops, there are no PPI records of HIS8_YEAST !! | ||||
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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