RL34B_YEAST - dbPTM
RL34B_YEAST - PTM Information in dbPTM
Basic Information of Protein
UniProt ID RL34B_YEAST
UniProt AC P40525
Protein Name 60S ribosomal protein L34-B {ECO:0000303|PubMed:9559554}
Gene Name RPL34B {ECO:0000303|PubMed:9559554}
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length 121
Subcellular Localization Cytoplasm .
Protein Description Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules. The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain. The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel..
Protein Sequence MAQRVTFRRRNPYNTRSNKIKVVKTPGGILRAQHVKKLATRPKCGDCGSALQGISTLRPRQYATVSKTHKTVSRAYGGSRCANCVKERIVRAFLIEEQKIVKKVVKEQTEAAKKSEKKSKK
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
19UbiquitinationPYNTRSNKIKVVKTP
CCCCCCCCEEEEECC		45.1922817900
21UbiquitinationNTRSNKIKVVKTPGG
CCCCCCEEEEECCCH		42.4522817900
242-HydroxyisobutyrylationSNKIKVVKTPGGILR
CCCEEEEECCCHHHH		52.57-
24AcetylationSNKIKVVKTPGGILR
CCCEEEEECCCHHHH		52.5724489116
24UbiquitinationSNKIKVVKTPGGILR
CCCEEEEECCCHHHH		52.5723749301
25PhosphorylationNKIKVVKTPGGILRA
CCEEEEECCCHHHHH		18.6323749301
43AcetylationKKLATRPKCGDCGSA
HHHCCCCCCCCHHHH		47.7825381059
43UbiquitinationKKLATRPKCGDCGSA
HHHCCCCCCCCHHHH		47.7823749301
49PhosphorylationPKCGDCGSALQGIST
CCCCCHHHHHHHHHC		31.9421440633
55PhosphorylationGSALQGISTLRPRQY
HHHHHHHHCCCHHHE		28.3721440633
67UbiquitinationRQYATVSKTHKTVSR
HHEEEECCCCCCHHH		50.7623749301
672-HydroxyisobutyrylationRQYATVSKTHKTVSR
HHEEEECCCCCCHHH		50.76-
70UbiquitinationATVSKTHKTVSRAYG
EEECCCCCCHHHHHC		56.7223749301
70AcetylationATVSKTHKTVSRAYG
EEECCCCCCHHHHHC		56.7225381059
702-HydroxyisobutyrylationATVSKTHKTVSRAYG
EEECCCCCCHHHHHC		56.72-
76PhosphorylationHKTVSRAYGGSRCAN
CCCHHHHHCCCHHHH		22.4021440633
86UbiquitinationSRCANCVKERIVRAF
CHHHHHHHHHHHHHH		43.4023749301
99SuccinylationAFLIEEQKIVKKVVK
HHHHHHHHHHHHHHH		53.3923954790
99UbiquitinationAFLIEEQKIVKKVVK
HHHHHHHHHHHHHHH		53.3923749301
99AcetylationAFLIEEQKIVKKVVK
HHHHHHHHHHHHHHH		53.3924489116
102UbiquitinationIEEQKIVKKVVKEQT
HHHHHHHHHHHHHHH		43.2422817900
103UbiquitinationEEQKIVKKVVKEQTE
HHHHHHHHHHHHHHH		41.1722817900
106UbiquitinationKIVKKVVKEQTEAAK
HHHHHHHHHHHHHHH		47.2823749301
106AcetylationKIVKKVVKEQTEAAK
HHHHHHHHHHHHHHH		47.2825381059
106SuccinylationKIVKKVVKEQTEAAK
HHHHHHHHHHHHHHH		47.2823954790
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of RL34B_YEAST !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of RL34B_YEAST !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of RL34B_YEAST !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
GCN4_YEASTGCN4genetic
18423200
RQC2_YEASTTAE2genetic
20691087
RTC6_YEASTRTC6genetic
20691087
EBP2_YEASTEBP2physical
25119672
NOP12_YEASTNOP12physical
25119672
RL2A_YEASTRPL2Agenetic
27708008
RL2B_YEASTRPL2Agenetic
27708008
RL40A_YEASTRPL40Bgenetic
27708008
RL40B_YEASTRPL40Bgenetic
27708008
EDE1_YEASTEDE1genetic
27708008
NU170_YEASTNUP170genetic
27708008
ARL1_YEASTARL1genetic
27708008
PAT1_YEASTPAT1genetic
27708008
SLX5_YEASTSLX5genetic
27708008
RPN4_YEASTRPN4genetic
27708008
RTN2_YEASTRTN2genetic
27708008
TREA_YEASTNTH1genetic
27708008
TVP15_YEASTTVP15genetic
27708008
ARO1_YEASTARO1genetic
27708008
YCFI_YEASTYCF1genetic
27708008
RKM2_YEASTRKM2genetic
27708008
SEM1_YEASTSEM1genetic
27708008
ACA1_YEASTACA1genetic
27708008
COG7_YEASTCOG7genetic
27708008
XRN1_YEASTXRN1genetic
27708008
GOSR1_YEASTGOS1genetic
27708008
ARP1_YEASTARP1genetic
27708008
SYS1_YEASTSYS1genetic
27708008
LSM1_YEASTLSM1genetic
27708008
MOG1_YEASTMOG1genetic
27708008
FRMSR_YEASTYKL069Wgenetic
27708008
DYHC_YEASTDYN1genetic
27708008
LDB18_YEASTLDB18genetic
27708008
RIC1_YEASTRIC1genetic
27708008
YPT6_YEASTYPT6genetic
27708008
GIS4_YEASTGIS4genetic
27708008
COG8_YEASTCOG8genetic
27708008
MOT3_YEASTMOT3genetic
27708008
JNM1_YEASTJNM1genetic
27708008
DYN3_YEASTDYN3genetic
27708008
COG6_YEASTCOG6genetic
27708008
COG5_YEASTCOG5genetic
27708008
TLG2_YEASTTLG2genetic
27708008
BUB3_YEASTBUB3genetic
27708008
RUD3_YEASTRUD3genetic
27708008
LIS1_YEASTPAC1genetic
27708008
ARL3_YEASTARL3genetic
27708008
AIM44_YEASTAIM44genetic
27708008
NIP80_YEASTNIP100genetic
27708008
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of RL34B_YEAST

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Related Literatures of Post-Translational Modification

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