MDJ2_YEAST - dbPTM
MDJ2_YEAST - PTM Information in dbPTM
Basic Information of Protein
UniProt ID MDJ2_YEAST
UniProt AC P42834
Protein Name Mitochondrial DnaJ homolog 2
Gene Name MDJ2
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length 146
Subcellular Localization Mitochondrion inner membrane .
Protein Description Plays a role in mitochondrial biogenesis and protein folding. Participates in the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner, probably by stimulating activity of mtHSP70 (SSC1)..
Protein Sequence MVLPIIIGLGVTMVALSVKSGLNAWTVYKTLSPLTIAKLNNIRIENPTAGYRDALKFKSSLIDEELKNRLNQYQGGFAPRMTEPEALLILDISAREINHLDEKLLKKKHRKAMVRNHPDRGGSPYMAAKINEAKEVLERSVLLRKR
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure
ASA (%) Reference Orthologous
Protein Cluster
103AcetylationEINHLDEKLLKKKHR
HCCHHCHHHHHHHHH
59.8024489116

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of MDJ2_YEAST !!

Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of MDJ2_YEAST !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10)
Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of MDJ2_YEAST !!

Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
TIM16_YEASTPAM16physical
16027163
TIM14_YEASTPAM18physical
16027163
TIM44_YEASTTIM44physical
16027163
EAF1_YEASTEAF1genetic
20093466
MED5_YEASTNUT1genetic
20093466
ROM2_YEASTROM2genetic
20093466
GBLP_YEASTASC1genetic
20093466
MED9_YEASTCSE2genetic
20093466
INO4_YEASTINO4genetic
20093466
TSR3_YEASTTSR3genetic
20093466
RS10A_YEASTRPS10Agenetic
20093466
HSP7F_YEASTSSE1genetic
20093466
ATC2_YEASTPMC1physical
16093310
RLA1_YEASTRPP1Agenetic
27708008
RU2A_YEASTLEA1genetic
27708008

Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of MDJ2_YEAST

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Related Literatures of Post-Translational Modification

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