ELOA1_YEAST - dbPTM
ELOA1_YEAST - PTM Information in dbPTM
Basic Information of Protein
UniProt ID ELOA1_YEAST
UniProt AC P53861
Protein Name Elongin-A
Gene Name ELA1
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length 379
Subcellular Localization
Protein Description
Protein Sequence MKSLQTLCEISLMRNHSNIQSVSNVPYHLLKRILQKVKIPQLLKLEKSNVLLIFDDDELWLEFLRQDFPTNVHEQFVSKRDIICKYYFDFVKENDIELYHSNQDLLKSCVRQSVVKDIRNNKYRIPYRMLYSKYQQEVEKKQEESAERLRLEMQKLQQEREKKQTIVVDHTVYFKKRNTKKTTRLHNEPHSQLYMKSLKDHESRLKHFKDGGFNIAKRHAQRVAFGGQAGGQSSSPKKGPLSIKPEPVKVNRQMDNVTAEKKDVTQPITPVKKRRSESPSIFLNRKKPALFRPTPKTNAAGSRPHTTAITNDHRTTSHPYPHKDVVTSISSVTANPVTKGHKKKKSGIFVRNAGSDGDSFPHVTATGPTTRPYIYEPRK
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure
ASA (%) Reference Orthologous
Protein Cluster
233PhosphorylationGGQAGGQSSSPKKGP
CCCCCCCCCCCCCCC
35.7430377154
234PhosphorylationGQAGGQSSSPKKGPL
CCCCCCCCCCCCCCC
42.6529734811
235PhosphorylationQAGGQSSSPKKGPLS
CCCCCCCCCCCCCCC
46.0825752575
269PhosphorylationKDVTQPITPVKKRRS
CCCCCCCCCCCCCCC
28.8121440633
276PhosphorylationTPVKKRRSESPSIFL
CCCCCCCCCCCCCCC
46.5929688323
278PhosphorylationVKKRRSESPSIFLNR
CCCCCCCCCCCCCCC
25.7921082442
280PhosphorylationKRRSESPSIFLNRKK
CCCCCCCCCCCCCCC
34.9429688323
306PhosphorylationAAGSRPHTTAITNDH
CCCCCCCCEEECCCC
22.1727017623
307PhosphorylationAGSRPHTTAITNDHR
CCCCCCCEEECCCCC
17.0227017623
310PhosphorylationRPHTTAITNDHRTTS
CCCCEEECCCCCCCC
31.9327017623

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of ELOA1_YEAST !!

Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of ELOA1_YEAST !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10)
Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of ELOA1_YEAST !!

Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
NOP12_YEASTNOP12physical
11805837
PUF6_YEASTPUF6physical
11805837
ERB1_YEASTERB1physical
11805837
NAT10_YEASTKRE33physical
11805837
YAK1_YEASTYAK1physical
11805837
PIL1_YEASTPIL1physical
11805837
RPF2_YEASTRPF2physical
11805837
LSP1_YEASTLSP1physical
11805837
MS116_YEASTMSS116physical
11805837
HSP7E_YEASTECM10physical
11805837
UTP22_YEASTUTP22physical
11805837
FBRL_YEASTNOP1physical
11805837
CIC1_YEASTCIC1physical
11805837
YTM1_YEASTYTM1physical
11805837
EBP2_YEASTEBP2physical
11805837
RRP12_YEASTRRP12physical
11805837
PWP1_YEASTPWP1physical
11805837
PT127_YEASTPET127physical
11805837
IMDH4_YEASTIMD4physical
11805837
MRX1_YEASTYER077Cphysical
11805837
CTH2_YEASTTIS11physical
11805837
IMDH3_YEASTIMD3physical
11805837
NOG1_YEASTNOG1physical
11805837
PESC_YEASTNOP7physical
11805837
LOC1_YEASTLOC1physical
11805837
YRA1_YEASTYRA1physical
11805837
HAT1_YEASTHAT1physical
11805837
ELOC_YEASTELC1physical
10753924
ELOC_YEASTELC1physical
10430890
ECM8_YEASTECM8genetic
20093466
SMP1_YEASTSMP1genetic
20093466
YC01A_YEASTYCL001W-Agenetic
20093466
ELO2_YEASTELO2genetic
20093466
CMR1_YEASTCMR1genetic
20093466
CEM1_YEASTCEM1genetic
20093466
RPOM_YEASTRPO41genetic
20093466
QCR9_YEASTQCR9genetic
20093466
OPI1_YEASTOPI1genetic
20093466
HTD2_YEASTHTD2genetic
20093466
YJH0_YEASTYJL070Cgenetic
20093466
VPS55_YEASTVPS55genetic
20093466
MOG1_YEASTMOG1genetic
20093466
FABG_YEASTOAR1genetic
20093466
MDM35_YEASTMDM35genetic
20093466
UTH1_YEASTUTH1genetic
20093466
RHO4_YEASTRHO4genetic
20093466
COX7_YEASTCOX7genetic
20093466
AEP2_YEASTAEP2genetic
20093466
CY1_YEASTCYT1genetic
20093466
WDR6_YEASTRTT10genetic
20093466
COX10_YEASTCOX10genetic
20093466
PEX10_YEASTPEX10genetic
27708008
SNF1_YEASTSNF1genetic
27708008
SIN3_YEASTSIN3genetic
27708008
MSS18_YEASTMSS18genetic
27708008
RL19A_YEASTRPL19Bgenetic
27708008
RL19B_YEASTRPL19Bgenetic
27708008
ECM8_YEASTECM8genetic
27708008
SMP1_YEASTSMP1genetic
27708008
YC01A_YEASTYCL001W-Agenetic
27708008
RIM1_YEASTRIM1genetic
27708008
ELO2_YEASTELO2genetic
27708008
TAH1_YEASTTAH1genetic
27708008
IMG2_YEASTIMG2genetic
27708008
BCS1_YEASTBCS1genetic
27708008
IRC4_YEASTIRC4genetic
27708008
CEM1_YEASTCEM1genetic
27708008
XRN1_YEASTXRN1genetic
27708008
QCR9_YEASTQCR9genetic
27708008
NPR3_YEASTNPR3genetic
27708008
HTD2_YEASTHTD2genetic
27708008
EMC5_YEASTEMC5genetic
27708008
TED1_YEASTTED1genetic
27708008
GPDM_YEASTGUT2genetic
27708008
LPLA_YEASTAIM22genetic
27708008
YJH0_YEASTYJL070Cgenetic
27708008
VPS55_YEASTVPS55genetic
27708008
MDM35_YEASTMDM35genetic
27708008
FABG_YEASTOAR1genetic
27708008
CBT1_YEASTCBT1genetic
27708008
LIPB_YEASTLIP2genetic
27708008
ITT1_YEASTITT1genetic
27708008
COX7_YEASTCOX7genetic
27708008
SWS2_YEASTSWS2genetic
27708008
HMI1_YEASTHMI1genetic
27708008
CY1_YEASTCYT1genetic
27708008
LIPA_YEASTLIP5genetic
27708008
COX10_YEASTCOX10genetic
27708008
HDA3_YEASTHDA3genetic
27708008
QCR2_YEASTQCR2genetic
27708008
SWI6_YEASTSWI6genetic
27453043
SSN3_YEASTSSN3genetic
27453043
PPA5_YEASTPHO5genetic
27453043

Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of ELOA1_YEAST

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Related Literatures of Post-Translational Modification
Phosphorylation
ReferencePubMed
"Analysis of phosphorylation sites on proteins from Saccharomycescerevisiae by electron transfer dissociation (ETD) massspectrometry.";
Chi A., Huttenhower C., Geer L.Y., Coon J.J., Syka J.E.P., Bai D.L.,Shabanowitz J., Burke D.J., Troyanskaya O.G., Hunt D.F.;
Proc. Natl. Acad. Sci. U.S.A. 104:2193-2198(2007).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-278, AND MASSSPECTROMETRY.

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