UniProt ID | ELOA1_YEAST | |
---|---|---|
UniProt AC | P53861 | |
Protein Name | Elongin-A | |
Gene Name | ELA1 | |
Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast). | |
Sequence Length | 379 | |
Subcellular Localization | ||
Protein Description | ||
Protein Sequence | MKSLQTLCEISLMRNHSNIQSVSNVPYHLLKRILQKVKIPQLLKLEKSNVLLIFDDDELWLEFLRQDFPTNVHEQFVSKRDIICKYYFDFVKENDIELYHSNQDLLKSCVRQSVVKDIRNNKYRIPYRMLYSKYQQEVEKKQEESAERLRLEMQKLQQEREKKQTIVVDHTVYFKKRNTKKTTRLHNEPHSQLYMKSLKDHESRLKHFKDGGFNIAKRHAQRVAFGGQAGGQSSSPKKGPLSIKPEPVKVNRQMDNVTAEKKDVTQPITPVKKRRSESPSIFLNRKKPALFRPTPKTNAAGSRPHTTAITNDHRTTSHPYPHKDVVTSISSVTANPVTKGHKKKKSGIFVRNAGSDGDSFPHVTATGPTTRPYIYEPRK | |
Overview of Protein Modification Sites with Functional and Structural Information | ||
* ASA = Accessible Surface Area
Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
---|---|---|---|---|---|
233 | Phosphorylation | GGQAGGQSSSPKKGP CCCCCCCCCCCCCCC | 35.74 | 30377154 | |
234 | Phosphorylation | GQAGGQSSSPKKGPL CCCCCCCCCCCCCCC | 42.65 | 29734811 | |
235 | Phosphorylation | QAGGQSSSPKKGPLS CCCCCCCCCCCCCCC | 46.08 | 25752575 | |
269 | Phosphorylation | KDVTQPITPVKKRRS CCCCCCCCCCCCCCC | 28.81 | 21440633 | |
276 | Phosphorylation | TPVKKRRSESPSIFL CCCCCCCCCCCCCCC | 46.59 | 29688323 | |
278 | Phosphorylation | VKKRRSESPSIFLNR CCCCCCCCCCCCCCC | 25.79 | 21082442 | |
280 | Phosphorylation | KRRSESPSIFLNRKK CCCCCCCCCCCCCCC | 34.94 | 29688323 | |
306 | Phosphorylation | AAGSRPHTTAITNDH CCCCCCCCEEECCCC | 22.17 | 27017623 | |
307 | Phosphorylation | AGSRPHTTAITNDHR CCCCCCCEEECCCCC | 17.02 | 27017623 | |
310 | Phosphorylation | RPHTTAITNDHRTTS CCCCEEECCCCCCCC | 31.93 | 27017623 |
Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of ELOA1_YEAST !! |
Modified Location | Modified Residue | Modification | Function | Reference | ||
---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of ELOA1_YEAST !! |
* Distance = the distance between SAP position and PTM sites.
Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of ELOA1_YEAST !! |
Kegg Drug | ||||||
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DrugBank | ||||||
There are no disease associations of PTM sites. |
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Phosphorylation | |
Reference | PubMed |
"Analysis of phosphorylation sites on proteins from Saccharomycescerevisiae by electron transfer dissociation (ETD) massspectrometry."; Chi A., Huttenhower C., Geer L.Y., Coon J.J., Syka J.E.P., Bai D.L.,Shabanowitz J., Burke D.J., Troyanskaya O.G., Hunt D.F.; Proc. Natl. Acad. Sci. U.S.A. 104:2193-2198(2007). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-278, AND MASSSPECTROMETRY. |