SMP1_YEAST - dbPTM
SMP1_YEAST - PTM Information in dbPTM
Basic Information of Protein
UniProt ID SMP1_YEAST
UniProt AC P38128
Protein Name Transcription factor SMP1
Gene Name SMP1
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length 452
Subcellular Localization Nucleus .
Protein Description Transcription factor that controls part of the HOG1-mediated osmostress responses. Binds to the DNA sequence 5'-ACTACTA[TA](4)TAG-3'. Does not appear to function in the MPK1 pathway..
Protein Sequence MGRRKIEIEPIKDDRNRTVTFIKRKAGLFKKAHELSVLCQVDIAVIILGSNNTFYEYSSVDMSNLLNVHQNNTDLPHNIIEPSDYGDYVKKPRVVLNERKRRRRRATVLQPASHSGSCTVSSQDSSSVQNNGNLSAPLASNDAGNAGVSTPLVHCHGAISRSGSNHSDCARNSADYQMLQGGLNSGGSFHANDYKESVDQQHVANEAIHRNFMNKRIRPDTHLLLSESNHSNYHNFYPSPYENLPKPSLPASLVGNIPSFQSQFVQVIPANSNPMGKGFNGTGDSESFEAKQKIHPTVAISNTLEGPAPVQAMVHHLHQLNSNRGKLSGKPYLKLNIPKATNDACQRSPAMYSGTASPKTDVQATPNQMLASNMSSPLSRSKFLGFKNNDMDDLYHNGRCGSTYVNNKTFFLKPPIGRPPKFPKSPSSSIVVFPSSVASSTLKSTSSTNSPD
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure
ASA (%) Reference Orthologous
Protein Cluster
348PhosphorylationTNDACQRSPAMYSGT
CCHHHHHCCCCCCCC
7.3728889911
353PhosphorylationQRSPAMYSGTASPKT
HHCCCCCCCCCCCCC
19.3127017623
357PhosphorylationAMYSGTASPKTDVQA
CCCCCCCCCCCCCCC
27.1128889911
360PhosphorylationSGTASPKTDVQATPN
CCCCCCCCCCCCCHH
44.8027017623
365PhosphorylationPKTDVQATPNQMLAS
CCCCCCCCHHHHHHH
12.9928889911
375PhosphorylationQMLASNMSSPLSRSK
HHHHHCCCCCCCHHH
32.8128889911
376PhosphorylationMLASNMSSPLSRSKF
HHHHCCCCCCCHHHH
21.0628889911
379PhosphorylationSNMSSPLSRSKFLGF
HCCCCCCCHHHHCCC
37.5827017623
425PhosphorylationRPPKFPKSPSSSIVV
CCCCCCCCCCCCEEE
30.1924961812
427PhosphorylationPKFPKSPSSSIVVFP
CCCCCCCCCCEEEEE
43.7524961812

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of SMP1_YEAST !!

Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of SMP1_YEAST !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10)
Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of SMP1_YEAST !!

Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
HOG1_YEASTHOG1physical
12482976
RLM1_YEASTRLM1physical
9121433
ATG17_YEASTATG17physical
18719252
RSP5_YEASTRSP5physical
18719252
MNN10_YEASTMNN10genetic
19269370
CSK2B_YEASTCKB1genetic
19269370
IES3_YEASTIES3genetic
19269370
PFD2_YEASTGIM4genetic
20959818
STB2_YEASTSTB2genetic
20959818
IES1_YEASTIES1genetic
20959818
HOT1_YEASTHOT1physical
21193057
MSN2_YEASTMSN2physical
21193057
MSN4_YEASTMSN4physical
21193057
EIF2A_YEASTYGR054Wgenetic
27708008
ICE2_YEASTICE2genetic
27708008
CSN12_YEASTYJR084Wgenetic
27708008
IDH2_YEASTIDH2genetic
27708008
MSS18_YEASTMSS18genetic
27708008
SLA1_YEASTSLA1genetic
27708008
RV161_YEASTRVS161genetic
27708008
YCQ6_YEASTYCR016Wgenetic
27708008
RIM1_YEASTRIM1genetic
27708008
RBSK_YEASTRBK1genetic
27708008
PP2C1_YEASTPTC1genetic
27708008
GPR1_YEASTGPR1genetic
27708008
VAM6_YEASTVAM6genetic
27708008
CRD1_YEASTCRD1genetic
27708008
FADH_YEASTSFA1genetic
27708008
AIR2_YEASTAIR2genetic
27708008
TPS2_YEASTTPS2genetic
27708008
ARX1_YEASTARX1genetic
27708008
IPK1_YEASTIPK1genetic
27708008
RL27B_YEASTRPL27Bgenetic
27708008
ICP55_YEASTICP55genetic
27708008
SHC1_YEASTSHC1genetic
27708008
SWI4_YEASTSWI4genetic
27708008
ERJ5_YEASTERJ5genetic
27708008
CGR1_YEASTCGR1genetic
27708008
TFS2_YEASTDST1genetic
27708008
RL9A_YEASTRPL9Agenetic
27708008
HUR1_YEASTHUR1genetic
27708008
SPO74_YEASTSPO74genetic
27708008
XRN1_YEASTXRN1genetic
27708008
VAM7_YEASTVAM7genetic
27708008
YGY5_YEASTYGL235Wgenetic
27708008
ASK10_YEASTASK10genetic
27708008
RIM4_YEASTRIM4genetic
27708008
SNF6_YEASTSNF6genetic
27708008
QCR10_YEASTQCR10genetic
27708008
NAM8_YEASTNAM8genetic
27708008
PTH_YEASTPTH1genetic
27708008
FMC1_YEASTFMC1genetic
27708008
PTPA1_YEASTRRD1genetic
27708008
IMPX_YEASTIMP2genetic
27708008
BNA3_YEASTBNA3genetic
27708008
RS21B_YEASTRPS21Bgenetic
27708008
RPA34_YEASTRPA34genetic
27708008
PIR5_YEASTYJL160Cgenetic
27708008
HSL1_YEASTHSL1genetic
27708008
FEN1_YEASTRAD27genetic
27708008
SAC1_YEASTSAC1genetic
27708008
RAD5_YEASTRAD5genetic
27708008
FRE8_YEASTFRE8genetic
27708008
STM1_YEASTSTM1genetic
27708008
YL456_YEASTYLR456Wgenetic
27708008
CTF18_YEASTCTF18genetic
27708008
RAD14_YEASTRAD14genetic
27708008
DIA1_YEASTDIA1genetic
27708008
MAS5_YEASTYDJ1genetic
27708008
IRA2_YEASTIRA2genetic
27708008
SGT2_YEASTSGT2genetic
27708008
HST3_YEASTHST3genetic
27708008
CY1_YEASTCYT1genetic
27708008
DIA2_YEASTDIA2genetic
27708008
WHI5_YEASTWHI5genetic
27708008
VPS21_YEASTVPS21genetic
27708008
LGE1_YEASTLGE1genetic
27708008
NCBP2_YEASTCBC2genetic
27708008
RTC6_YEASTRTC6genetic
27708008
KAR3_YEASTKAR3genetic
27708008
QCR2_YEASTQCR2genetic
27708008
PLS4_HUMANPLSCR4physical
27107014
IMA4_HUMANKPNA3physical
27107014
TRI27_HUMANTRIM27physical
27107014
PP2AB_HUMANPPP2CBphysical
27107014
DVL2_HUMANDVL2physical
27107014
GOGA2_HUMANGOLGA2physical
27107014

Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of SMP1_YEAST

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Related Literatures of Post-Translational Modification

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