| UniProt ID | MRX1_YEAST | |
|---|---|---|
| UniProt AC | P40050 | |
| Protein Name | MIOREX complex component 1 {ECO:0000305|PubMed:25683707} | |
| Gene Name | MRX1 {ECO:0000303|PubMed:25683707} | |
| Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast). | |
| Sequence Length | 688 | |
| Subcellular Localization | Mitochondrion . | |
| Protein Description | Component of MIOREX complexes, large expressome-like assemblies of ribosomes with factors involved in all the steps of post-transcriptional gene expression.. | |
| Protein Sequence | MGLKITKGQLRTKDLNQSSSKSSQSSRIGVDTCIFTRMLPRINTAINLTEHLLRRSFHSLTNLQKTQVKERLHELERHGFILNKTSKQLERINSKKRRQLKKLQKTAYPKDQAFHILRKFHKINNEALADTKLGPTSQSDLKFLSLTKDKRLFYTILGVNGEQLRDSKLIANDVQKFLKRGQLEKAVFLARLAKKKGVVGMNLIMKYYIEVVQSQQSAVDIFNWRKKWGVPIDQHSITILFNGLSKQENLVSKKYGELVLKTIDSLCDKNELTEIEYNTALAALINCTDETLVFKLLNKKCPGLKKDSITYTLMIRSCTRIADEKRFMVVLNDLMNKIPDYCVDSKLLFEYCEVICSQKSPKIEKQGMGLWALCEYFQFDKTIFKKYLTQSDFPTLVPLSHWNINKPFPLNKHVVGLFMNYCLKNKEYDLAMEIFKTLEAQNNQMLDQSIYHKYMETVITTRPITCGDECLDIYERVASSAQISITRRTLILVYNAFQRQSLKAVINKDASNAEATLHKIRGFIDSVEATYSSKLNGKVYRFNSWKFLFPIVKNLNMNDKVSTVELKSILDEYLKSLLNGEFGKEFKASIEDKRFVTLEGIRLVKVLTERIKLPSLDSEEIASLKGTERKKFLARRHLLRLKQILLEDLADIEGNSRRKGDSENTSTSEERIMEDLAELILETSYDKF | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 7 | Acetylation | -MGLKITKGQLRTKD -CCCCCCCCCCCCCC | 25381059 | ||
| 131 | Phosphorylation | NNEALADTKLGPTSQ CCHHHCCCCCCCCCH | 29136822 | ||
| 136 | Phosphorylation | ADTKLGPTSQSDLKF CCCCCCCCCHHHHHH | 29136822 | ||
| 137 | Phosphorylation | DTKLGPTSQSDLKFL CCCCCCCCHHHHHHH | 29136822 | ||
| 139 | Phosphorylation | KLGPTSQSDLKFLSL CCCCCCHHHHHHHHC | 29136822 | ||
| 154 | Phosphorylation | TKDKRLFYTILGVNG CCCHHHEEEEECCCH | 19779198 | ||
| 288 | Phosphorylation | LAALINCTDETLVFK HHHHHCCCCHHHHHH | 27017623 | ||
| 291 | Phosphorylation | LINCTDETLVFKLLN HHCCCCHHHHHHHHC | 27017623 | ||
| 376 | Phosphorylation | GLWALCEYFQFDKTI HHHHHHHHHCCCHHH | 27017623 | ||
| 589 | Phosphorylation | FGKEFKASIEDKRFV CCHHHHCCCCCCCEE | 27017623 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of MRX1_YEAST !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of MRX1_YEAST !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of MRX1_YEAST !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
| CHA4_YEAST | CHA4 | genetic | 27708008 | |
| RNY1_YEAST | RNY1 | genetic | 27708008 | |
| PRS4_YEAST | RPT2 | genetic | 27708008 | |
| CDC13_YEAST | CDC13 | genetic | 27708008 | |
| ACT_YEAST | ACT1 | genetic | 27708008 | |
| CDC14_YEAST | CDC14 | genetic | 27708008 | |
| PRS8_YEAST | RPT6 | genetic | 27708008 | |
| TEL2_YEAST | TEL2 | genetic | 27708008 | |
| TIM44_YEAST | TIM44 | genetic | 27708008 | |
| HYM1_YEAST | HYM1 | genetic | 27708008 | |
| PSB5_YEAST | PRE2 | genetic | 27708008 | |
| GEM1_YEAST | GEM1 | genetic | 27708008 | |
| SPS2_YEAST | SPS2 | genetic | 27708008 | |
| AVL9_YEAST | AVL9 | genetic | 27708008 |
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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