| UniProt ID | PPA5_YEAST | |
|---|---|---|
| UniProt AC | P00635 | |
| Protein Name | Repressible acid phosphatase | |
| Gene Name | PHO5 | |
| Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast). | |
| Sequence Length | 467 | |
| Subcellular Localization | Secreted. | |
| Protein Description | Partially mediates extracellular nucleotide derived phosphate hydrolysis along with NPP1 and NPP2.. | |
| Protein Sequence | MFKSVVYSILAASLANAGTIPLGKLADVDKIGTQKDIFPFLGGAGPYYSFPGDYGISRDLPEGCEMKQLQMVGRHGERYPTVSLAKTIKSTWYKLSNYTRQFNGSLSFLNDDYEFFIRDDDDLEMETTFANSDDVLNPYTGEMNAKRHARDFLAQYGYMVENQTSFAVFTSNSKRCHDTAQYFIDGLGDQFNITLQTVSEAESAGANTLSACNSCPAWDYDANDDIVNEYDTTYLDDIAKRLNKENKGLNLTSTDASTLFSWCAFEVNAKGYSDVCDIFTKDELVHYSYYQDLHTYYHEGPGYDIIKSVGSNLFNASVKLLKQSEIQDQKVWLSFTHDTDILNFLTTAGIIDDKNNLTAEYVPFMGNTFHRSWYVPQGARVYTEKFQCSNDTYVRYVINDAVVPIETCSTGPGFSCEINDFYDYAEKRVAGTDFLKVCNVSSVSNSTELTFYWDWNTTHYNASLLRQ | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 7 | Phosphorylation | -MFKSVVYSILAASL -CCHHHHHHHHHHHH | 6.45 | 29688323 | |
| 8 | Phosphorylation | MFKSVVYSILAASLA CCHHHHHHHHHHHHH | 10.26 | 29688323 | |
| 13 | Phosphorylation | VYSILAASLANAGTI HHHHHHHHHHHCCCC | 23.54 | 29688323 | |
| 19 | Phosphorylation | ASLANAGTIPLGKLA HHHHHCCCCCCCHHC | 19.60 | 29688323 | |
| 97 | N-linked_Glycosylation | STWYKLSNYTRQFNG HHHHHHHHCEEEECC | 53.27 | - | |
| 103 | N-linked_Glycosylation | SNYTRQFNGSLSFLN HHCEEEECCEEEECC | 30.70 | - | |
| 162 | N-linked_Glycosylation | QYGYMVENQTSFAVF HHCCEECCCCEEEEE | 38.73 | - | |
| 192 | N-linked_Glycosylation | DGLGDQFNITLQTVS CCCHHHEEEEEEEHH | 22.24 | - | |
| 230 | Phosphorylation | NDDIVNEYDTTYLDD CCCHHHHCCCHHHHH | 17.24 | 22369663 | |
| 232 | Phosphorylation | DIVNEYDTTYLDDIA CHHHHCCCHHHHHHH | 19.21 | 22369663 | |
| 233 | Phosphorylation | IVNEYDTTYLDDIAK HHHHCCCHHHHHHHH | 21.13 | 22369663 | |
| 234 | Phosphorylation | VNEYDTTYLDDIAKR HHHCCCHHHHHHHHH | 15.38 | 22369663 | |
| 250 | N-linked_Glycosylation | NKENKGLNLTSTDAS CCCCCCCCCCCCCHH | 50.36 | - | |
| 315 | N-linked_Glycosylation | SVGSNLFNASVKLLK HHHHHHHHHHHHHHH | 34.18 | - | |
| 356 | N-linked_Glycosylation | GIIDDKNNLTAEYVP CCCCCCCCEEEEEEE | 44.50 | - | |
| 390 | N-linked_Glycosylation | TEKFQCSNDTYVRYV EEEEECCCCCEEEEE | 53.95 | - | |
| 432 | Phosphorylation | AEKRVAGTDFLKVCN HHHHCCCCCEEEECC | 17.53 | 19795423 | |
| 439 | N-linked_Glycosylation | TDFLKVCNVSSVSNS CCEEEECCCCCCCCC | 39.43 | - | |
| 445 | N-linked_Glycosylation | CNVSSVSNSTELTFY CCCCCCCCCCEEEEE | 51.28 | - | |
| 456 | N-linked_Glycosylation | LTFYWDWNTTHYNAS EEEEEECCCCCCCHH | 32.40 | - | |
| 461 | N-linked_Glycosylation | DWNTTHYNASLLRQ- ECCCCCCCHHHHCC- | 18.56 | - |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of PPA5_YEAST !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of PPA5_YEAST !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of PPA5_YEAST !! | ||||||
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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