JHD2_YEAST - dbPTM
JHD2_YEAST - PTM Information in dbPTM
Basic Information of Protein
UniProt ID JHD2_YEAST
UniProt AC P47156
Protein Name Histone demethylase JHD2
Gene Name JHD2
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length 728
Subcellular Localization Nucleus .
Protein Description Histone demethylase that demethylates 'Lys-4' of histone H3, thereby playing a central role in histone code. Demethylates trimethylated H3 'Lys-4'..
Protein Sequence MEEIPALYPTEQEFKNPIDYLSNPHIKRLGVRYGMVKVVPPNGFCPPLSIDMENFTFQPRIQNLENLDLKNRCRLFFMKQLNNFKRSVKDPSKLILREPYTIVEYSDSTHASEILKKKVYFYDVFSELIKDNRTLTDTTQSFRRKLKFRDISQLRGDISLWRTISKKFNVPIGLLKEIFEKYIASYYIFLHSLNENVHTALHADQYPKSLLSDDEDDFDLGPDSNSGSDFEEDDDDACIVCRKTNDPKRTILCDSCDKPFHIYCLSPPLERVPSGDWICNTCIVGNGYYGFTQDTHDYSLPEFQEYCKRQNSRLLPARKLSIDELEEMFWSLVTKNRRSSLTTVKYGADIHNELPGQITGFPTREFIPKNINGDELIDYLKYCDHPMNLTNLPMAHNSLLPLFKRNISGMTIPWIYIGSLFSTFCWHMEDQYTLSANYQHEGDPKVWYSIPESGCTKFNDLLNDMSPDLFIKQPDLLHQLVTLISPYDPNFKKSGIPVYKAVQKPNEYIITFPKCYHAGFNTGYNFNEAVNFTIDFWLPYGFGAITDYKLTQKACVFDMFDLMINVLDKYNKDTLLFNDAFVRQCYSSLIVFYNTELKRIRKIQAIVPRTTLLEVHTDPNDEDEEYDIFCSQCKTICSIAFVLRKNNYDSIRTYKRHKKNHLSIRQWNELSTTDSKVSILCTQDYLKSIQNLNNSDGEEPYIDDELYFTKSLKDIDSLIKQVGVKLDR
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
340PhosphorylationVTKNRRSSLTTVKYG
HHCCCCCCCEEEEEC		28.1130377154
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of JHD2_YEAST !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of JHD2_YEAST !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of JHD2_YEAST !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
FUN30_YEASTFUN30physical
16554755
SAS10_YEASTSAS10physical
16554755
UTP25_YEASTUTP25physical
16554755
MAD3_YEASTMAD3genetic
17314980
ASK10_YEASTASK10genetic
17314980
UBR1_YEASTUBR1genetic
17314980
BMH1_YEASTBMH1genetic
17314980
UBP3_YEASTUBP3genetic
17314980
RV161_YEASTRVS161genetic
17314980
UBX1_YEASTSHP1genetic
17314980
CSK2B_YEASTCKB1genetic
17314980
HTL1_YEASTHTL1genetic
17314980
FUN30_YEASTFUN30genetic
17314980
MRC1_YEASTMRC1genetic
17314980
H3_YEASTHHT1physical
17310254
H3_YEASTHHT1physical
17875926
AF9_YEASTYAF9genetic
19547744
RAD9_YEASTRAD9genetic
19547744
NOT4_YEASTMOT2genetic
19346402
JHD2_YEASTJHD2physical
20538609
H3_YEASTHHT1physical
23091032
NOT4_YEASTMOT2genetic
24489688
RS29A_YEASTRPS29Agenetic
27708008
INO4_YEASTINO4genetic
27708008
CDC37_YEASTCDC37genetic
27708008
MOB2_YEASTMOB2genetic
27708008
NBP35_YEASTNBP35genetic
27708008
STS1_YEASTSTS1genetic
27708008
ARP4_YEASTARP4genetic
27708008
DPB11_YEASTDPB11genetic
27708008
DCP2_YEASTDCP2genetic
27708008
YBB0_YEASTYBL010Cgenetic
27708008
GPT1_YEASTSCT1genetic
27708008
MNN2_YEASTMNN2genetic
27708008
SIF2_YEASTSIF2genetic
27708008
RRT12_YEASTRRT12genetic
27708008
CSM1_YEASTCSM1genetic
27708008
YCY0_YEASTYCR090Cgenetic
27708008
NDH2_YEASTNDE2genetic
27708008
YD180_YEASTYDL180Wgenetic
27708008
RM01_YEASTMRPL1genetic
27708008
ODO2_YEASTKGD2genetic
27708008
RPA14_YEASTRPA14genetic
27708008
IES1_YEASTIES1genetic
27708008
DLDH_YEASTLPD1genetic
27708008
YGS6_YEASTYGL176Cgenetic
27708008
PHB2_YEASTPHB2genetic
27708008
HTD2_YEASTHTD2genetic
27708008
MDM35_YEASTMDM35genetic
27708008
FABG_YEASTOAR1genetic
27708008
COX12_YEASTCOX12genetic
27708008
PET8_YEASTPET8genetic
27708008
LIPA_YEASTLIP5genetic
27708008
NIP80_YEASTNIP100genetic
27708008
MDL2_YEASTMDL2genetic
27708008
SPP1_YEASTSPP1genetic
27897198
SET1_YEASTSET1genetic
27897198
H2A1_YEASTHTA1physical
26451043
SPT5_YEASTSPT5physical
28138513
PRP43_YEASTPRP43physical
28138513
PBP1_YEASTPBP1physical
28138513
PABP_YEASTPAB1physical
28138513
HRP1_YEASTHRP1physical
28138513
PUB1_YEASTPUB1physical
28138513
SUB2_YEASTSUB2physical
28138513
FIP1_YEASTFIP1physical
28138513
YRA1_YEASTYRA1physical
28138513
LSM12_YEASTLSM12physical
28138513
PBP4_YEASTPBP4physical
28138513
JHD2_YEASTJHD2physical
28138513
CFT2_YEASTCFT2physical
28138513
PFS2_YEASTPFS2physical
28138513
MPE1_YEASTMPE1physical
28138513
PTI1_YEASTPTI1physical
28138513
REF2_YEASTREF2physical
28138513
PAP_YEASTPAP1physical
28138513
RNA15_YEASTRNA15physical
28138513
RNA14_YEASTRNA14physical
28138513
PCF11_YEASTPCF11physical
28138513
SSN8_YEASTSSN8genetic
28143948
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of JHD2_YEAST

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Related Literatures of Post-Translational Modification

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