RED1_YEAST - dbPTM
RED1_YEAST - PTM Information in dbPTM
Basic Information of Protein
UniProt ID RED1_YEAST
UniProt AC P14291
Protein Name Protein RED1
Gene Name RED1
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length 827
Subcellular Localization Nucleus.
Protein Description Probable constituent of the synaptonemal complex during meiosis. May interact with HOP1. Required for meiosis I chromosome segregation..
Protein Sequence MEGLKKKIFGVCLKNDLAQTRNETKGIHYGLMTLETSKQLQEFLHLLVIKREVIQNFELLFHIINVAVKITDSNLPSDDIWHFILKLRFSSEINIDEDSKVLNYLLETGIAMENPVSWKCLAVISSILSSVPQSKKIITNLIETEHAKKIGQLFDNIQDLQQGNFLVEILSNCFKKSASNSKKVEKIPQLWQSRSKNKFFFENEFYPFSSKNGSLQTCQFLCNNFMSTLSFTGILRQVSYSGSETLKNLRIFKKKDDENSYFIQCIYNKIYLWLDEKAPLEFERKKIRITKNLKNKIQIKLRQPFHECVRTTADKTALLFNKTKGFQLEFEDEKLGETFFHNVNNIPKISEVQNFLVLDYIEEEPENEGEEEEQIGRADEQKEDEEEESLDELSTPMVYPIKSSIPHNHNEKVQLVTPDRSVSIRSDEWDLKSNTEDEEGNVLADLKISSTKETKRQTDYVHIDSEDQSPVVSAQMRKMRRESTKTLEILRQEFKDKDVQNKEDQSEQIQNPFVNTSSLVVGKSCLVNPKEKPNIDQTVVGITELKSNSSIKKRDINILDTIFGQPPSKKQKQFHKKEKKKQQKKLTNFKPIIDVPSQDKRNLRSNAPTKPKSIKVSKLRTDKKVTGEKSSPETAAEKVDDQTVRSNDEQAMSRATKEKCFPDVNEGKEITKDDAKVSLESKKNNETFVDSSVVEKHTPPDKDCNNCNITDILESTTVIDLQSPHGLSAPGQNTFTNKLQEQIYSSINHFSNELVRKISIINQELNKKILKELSEKYQKLFSELQDNFQNDTNEMLKFMGEIKDMMNLPEDQLVHAIRTRKFDNNKR
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure
ASA (%) Reference Orthologous
Protein Cluster
389PhosphorylationKEDEEEESLDELSTP
CCHHHHHCHHHCCCC
44.3827214570
395PhosphorylationESLDELSTPMVYPIK
HCHHHCCCCCEEECC
28.2021173162
403PhosphorylationPMVYPIKSSIPHNHN
CCEEECCCCCCCCCC
33.9321173162
404PhosphorylationMVYPIKSSIPHNHNE
CEEECCCCCCCCCCC
34.8321173162
417PhosphorylationNEKVQLVTPDRSVSI
CCCCEEECCCCCEEE
28.2327214570
421PhosphorylationQLVTPDRSVSIRSDE
EEECCCCCEEECCCC
27.8327214570
423PhosphorylationVTPDRSVSIRSDEWD
ECCCCCEEECCCCCC
17.3327214570
433PhosphorylationSDEWDLKSNTEDEEG
CCCCCCCCCCCCCCC
57.1721173162
435PhosphorylationEWDLKSNTEDEEGNV
CCCCCCCCCCCCCCE
52.4821173162
450PhosphorylationLADLKISSTKETKRQ
EEEEEECCCCCCCCC
47.1524930733
469PhosphorylationHIDSEDQSPVVSAQM
EECCCCCCHHHHHHH
31.8021173162
550PhosphorylationTELKSNSSIKKRDIN
EECCCCCCCCHHHCC
42.5521173162
597PhosphorylationKPIIDVPSQDKRNLR
CCCCCCCCHHCCCHH
51.3527214570
631PhosphorylationKVTGEKSSPETAAEK
CCCCCCCCHHHHHHH
37.5121173162
691PhosphorylationNNETFVDSSVVEKHT
CCCCCCCHHHHCCCC
21.5227214570
698PhosphorylationSSVVEKHTPPDKDCN
HHHHCCCCCCCCCCC
47.8121173162
723PhosphorylationTTVIDLQSPHGLSAP
CEEEECCCCCCCCCC
26.5921173162

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of RED1_YEAST !!

Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of RED1_YEAST !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10)
Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of RED1_YEAST !!

Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
SEC7_YEASTSEC7physical
11805837
MEK1_YEASTMEK1physical
9832507
MEK1_YEASTMEK1physical
10786836
PP12_YEASTGLC7physical
10786836
HOP1_YEASTHOP1physical
9060462
RED1_YEASTRED1physical
9286666
RED1_YEASTRED1physical
10958662
MEK1_YEASTMEK1genetic
14595109
ZIP1_YEASTZIP1genetic
8799151
SPO13_YEASTSPO13genetic
3413075
HOP1_YEASTHOP1physical
16221890
HED1_YEASTHED1genetic
16818607
AIM4_YEASTAIM4genetic
17314980
SSN2_YEASTSSN2genetic
17314980
TOP3_YEASTTOP3genetic
17314980
BUG1_YEASTBUG1genetic
17314980
FUS3_YEASTFUS3genetic
17314980
ODPA_YEASTPDA1genetic
17314980
MNN10_YEASTMNN10genetic
17314980
CSK2B_YEASTCKB1genetic
17314980
SMT3_YEASTSMT3physical
11283351
SMT3_YEASTSMT3physical
20534433
UBC9_YEASTUBC9physical
20534433
HOP1_YEASTHOP1genetic
10958662
PCH2_YEASTPCH2genetic
24465650
REC8_YEASTREC8physical
26258962
CHK1_YEASTCHK1genetic
27708008
THRC_YEASTTHR4genetic
27708008
YCY0_YEASTYCR090Cgenetic
27708008
MDHP_YEASTMDH3genetic
27708008
SAC3_YEASTSAC3genetic
27708008
LIC4_YEASTATC1genetic
27708008
GIC2_YEASTGIC2genetic
27708008
RTF1_YEASTRTF1genetic
27708008
SUCA_YEASTLSC1genetic
27708008
HOP1_YEASTHOP1physical
29186573
MAS5_YEASTYDJ1genetic
29674565
CHO2_YEASTCHO2genetic
29674565
CHL1_YEASTCHL1genetic
29674565
GGPPS_YEASTBTS1genetic
29674565

Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of RED1_YEAST

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Related Literatures of Post-Translational Modification

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