MSC2_YEAST - dbPTM
MSC2_YEAST - PTM Information in dbPTM
Basic Information of Protein
UniProt ID MSC2_YEAST
UniProt AC Q03455
Protein Name Probable zinc transporter MSC2
Gene Name MSC2
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length 724
Subcellular Localization Endoplasmic reticulum membrane
Multi-pass membrane protein . Nucleus membrane
Multi-pass membrane protein .
Protein Description Probably act as a zinc ion transporter moving zinc from the nucleus/endoplasmic reticulum to the cytoplasm. Involved in zinc ion homeostasis and cellular distribution..
Protein Sequence MNLQELLAKVPLLLSYPTIILSSNLIVPSHNDLISRAASTSAAEYADEKLIFFSTDHAIRLIFLPTFVASSFNLFAHYFNFINYSSRRKYYVLFTAIYFLSILTAIFHPIQSTCITLLIIKLLTTADESSPKIALNFKTILKTFVPFITLTLVILRWDPSFDASSGDVNKISTSLAAYALLILTLRYASPLILSTLSSSIGVVSKDTSVAQHSISRNKRFPLILVLPIFSFVLLYLMTIVNKTYNIQLLMVFVFFGCLSIFFLSLKDLFTEDGNQKKGGQEDEYCRMFDIKYMISYLWLTRFTILLTGIMAIVVHFLSFNEITSSIKTDLLSLLFVVVAEYVSSFSNKQPDSHSHNHAHHHSHLTDSLPLENESMFKQMALNKDTRSIFSFLLLNTAFMFVQLLYSFRSKSLGLLSDSLHMALDCTSLLLGLIAGVLTKKPASDKFPFGLNYLGTLAGFTNGVLLLGIVCGIFVEAIERIFNPIHLHATNELLVVATLGLLVNLVGLFAFDHGAHDHGGTDNENMKGIFLHILADTLGSVGVVISTLLIKLTHWPIFDPIASLLIGSLILLSALPLLKSTSANILLRLDDKKHNLVKSALNQISTTPGITGYTTPRFWPTESGSSGHSHAHTHSHAENHSHEHHHDQKNGSQEHPSLVGYIHVQYVDGENSTIIKKRVEKIFENVSIKAWVQVEPQNSTCWCRATSMNTISANPNSLPLQPIAN
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure
ASA (%) Reference Orthologous
Protein Cluster

Oops, there are no PTM records of MSC2_YEAST !!

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of MSC2_YEAST !!

Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of MSC2_YEAST !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10)
Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of MSC2_YEAST !!

Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
ZRG17_YEASTZRG17physical
15961382
HS150_YEASTHSP150genetic
15961382
SEC22_YEASTSEC22genetic
16269340
RTN1_YEASTRTN1genetic
16269340
PMT4_YEASTPMT4genetic
16269340
ZRG17_YEASTZRG17physical
11283351
ZRG17_YEASTZRG17physical
18719252
SIN3_YEASTSIN3genetic
19547744
XYL2_YEASTXYL2genetic
27708008
YL287_YEASTYLR287Cgenetic
27708008
RTG3_YEASTRTG3genetic
27708008
H3_YEASTHHT1genetic
27708008
ECM8_YEASTECM8genetic
27708008
BCS1_YEASTBCS1genetic
27708008
RLA4_YEASTRPP2Bgenetic
27708008
RV167_YEASTRVS167genetic
27708008
NPR3_YEASTNPR3genetic
27708008
SLT2_YEASTSLT2genetic
27708008
ARP1_YEASTARP1genetic
27708008
SDS3_YEASTSDS3genetic
27708008
FYV10_YEASTFYV10genetic
27708008
ILM1_YEASTILM1genetic
27708008
SAC1_YEASTSAC1genetic
27708008
DOA1_YEASTDOA1genetic
27708008
DID2_YEASTDID2genetic
27708008
ENV10_YEASTENV10genetic
27708008
ARP6_YEASTARP6genetic
27708008
SHH4_YEASTSHH4genetic
27708008
RS30A_YEASTRPS30Agenetic
27708008
RS30B_YEASTRPS30Agenetic
27708008
UBC12_YEASTUBC12genetic
27708008
RL31B_YEASTRPL31Bgenetic
27708008
FAR3_YEASTFAR3genetic
27708008
PFKA2_YEASTPFK2genetic
27708008
MRE11_YEASTMRE11genetic
27708008
SAP30_YEASTSAP30genetic
27708008
SIN3_YEASTSIN3genetic
27708008
HMI1_YEASTHMI1genetic
27708008
MSN1_YEASTMSN1genetic
27708008
GLO4_YEASTGLO4genetic
27708008
MCH5_YEASTMCH5genetic
27708008
RL21B_YEASTRPL21Bgenetic
27708008

Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of MSC2_YEAST

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Related Literatures of Post-Translational Modification

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