PEX15_YEAST - dbPTM
PEX15_YEAST - PTM Information in dbPTM
Basic Information of Protein
UniProt ID PEX15_YEAST
UniProt AC Q08215
Protein Name Peroxisomal membrane protein PEX15
Gene Name PEX15
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length 383
Subcellular Localization Endoplasmic reticulum membrane
Single-pass membrane protein . Peroxisome membrane
Single-pass membrane protein .
Protein Description Essential for the biogenesis of peroxisomes. Has a role in anchoring PEX6 onto the peroxisomal membrane..
Protein Sequence MAASEIMNNLPMHSLDSSLRDLLNDDLFIESDESTKSVNDQRSEVFQECVNLFIKRDIKDCLEKMSEVGFIDITVFKSNPMILDLFVSACDIMPSFTKLGLTLQSEILNIFTLDTPQCIETRKIILGDLSKLLVINKFFRCCIKVIQFNLTDHTEQEEKTLELESIMSDFIFVYITKMRTTIDVVGLQELIEIFIFQVKVKLHHKKPSPNMYWALCKTLPKLSPTLKGLYLSKDVSIEDAILNSIDNKIQKDKAKSKGKQRGVKQKIHHFHEPMLHNSSEEQVKVEDAFNQRTSTDSRLQSTGTAPRKKNNDITVLAGSFWAVLKHHFTRSVLNKNGLLLTGLLLLLCLKKYKSLMAIFKHVPAAFHTVYPQIVGLLKLLASI
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
4Phosphorylation----MAASEIMNNLP
----CCHHHHHHCCC		20.3728132839
17PhosphorylationLPMHSLDSSLRDLLN
CCCCCCCHHHHHHHC		36.2428132839
18PhosphorylationPMHSLDSSLRDLLND
CCCCCCHHHHHHHCC		27.3928132839
66PhosphorylationKDCLEKMSEVGFIDI
HHHHHHHHHCCCEEE		39.9519823750
74PhosphorylationEVGFIDITVFKSNPM
HCCCEEEEEECCCHH		19.0119823750
297PhosphorylationNQRTSTDSRLQSTGT
HCCCCCCHHHHCCCC		34.6723749301
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of PEX15_YEAST !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of PEX15_YEAST !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of PEX15_YEAST !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
PEX6_YEASTPEX6physical
12808025
PEX1_YEASTPEX1physical
16911527
PEX6_YEASTPEX6physical
16911527
PEX5_YEASTPEX5physical
16911527
PEX13_YEASTPEX13physical
16911527
PEX14_YEASTPEX14physical
16911527
PEX17_YEASTPEX17physical
16911527
PEX10_YEASTPEX10physical
16911527
PEX8_YEASTPEX8physical
16911527
PEX11_YEASTPEX11physical
18467557
SRS2_YEASTSRS2genetic
21459050
HSP71_YEASTSSA1physical
22940862
HSP72_YEASTSSA2physical
22940862
ATG36_YEASTATG36genetic
24657987
PEX1_YEASTPEX1physical
16007078
PEX15_YEASTPEX15physical
16007078
PEX6_YEASTPEX6physical
16007078
PEX3_YEASTPEX3physical
21098289
PEX13_YEASTPEX13genetic
27708008
MOB2_YEASTMOB2genetic
27708008
EXO70_YEASTEXO70genetic
27708008
AFG2_YEASTAFG2genetic
27708008
CAP_YEASTSRV2genetic
27708008
RPA1_YEASTRPA190genetic
27708008
LDS1_YEASTLDS1genetic
27708008
RS8A_YEASTRPS8Agenetic
27708008
RS8B_YEASTRPS8Agenetic
27708008
ETR1_YEASTETR1genetic
27708008
ODPB_YEASTPDB1genetic
27708008
NHP10_YEASTNHP10genetic
27708008
MTU1_YEASTSLM3genetic
27708008
RL13A_YEASTRPL13Agenetic
27708008
ATG9_YEASTATG9genetic
27708008
RPA14_YEASTRPA14genetic
27708008
EXG2_YEASTEXG2genetic
27708008
TPA1_YEASTTPA1genetic
27708008
RAD4_YEASTRAD4genetic
27708008
ODPA_YEASTPDA1genetic
27708008
XRN1_YEASTXRN1genetic
27708008
FMP48_YEASTFMP48genetic
27708008
BUB1_YEASTBUB1genetic
27708008
YOR1_YEASTYOR1genetic
27708008
NPR3_YEASTNPR3genetic
27708008
HTD2_YEASTHTD2genetic
27708008
YHT1_YEASTYHR131Cgenetic
27708008
CSM2_YEASTCSM2genetic
27708008
ATG32_YEASTATG32genetic
27708008
VPS53_YEASTVPS53genetic
27708008
LPLA_YEASTAIM22genetic
27708008
CSN12_YEASTYJR084Wgenetic
27708008
FABG_YEASTOAR1genetic
27708008
TRM2_YEASTTRM2genetic
27708008
SDHB_YEASTSDH2genetic
27708008
SRL2_YEASTSRL2genetic
27708008
ADY4_YEASTADY4genetic
27708008
YL346_YEASTYLR346Cgenetic
27708008
SRR1L_YEASTBER1genetic
27708008
HXT2_YEASTHXT2genetic
27708008
DIA1_YEASTDIA1genetic
27708008
LSM7_YEASTLSM7genetic
27708008
MSO1_YEASTMSO1genetic
27708008
PMA2_YEASTPMA2genetic
27708008
ALDH6_YEASTALD6genetic
27708008
UBA3_YEASTUBA3genetic
27708008
ATG13_YEASTATG13genetic
27708008
PEX6_YEASTPEX6physical
26842748
PEX1_YEASTPEX1physical
26842748
PEX3_YEASTPEX3physical
28906250
PEX6_YEASTPEX6physical
29321502
PEX1_YEASTPEX1physical
29321502
PEX5_YEASTPEX5physical
29321502
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of PEX15_YEAST

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Related Literatures of Post-Translational Modification

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