PEX1_YEAST - dbPTM
PEX1_YEAST - PTM Information in dbPTM
Basic Information of Protein
UniProt ID PEX1_YEAST
UniProt AC P24004
Protein Name Peroxisomal ATPase PEX1
Gene Name PEX1
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length 1043
Subcellular Localization Cytoplasm . Peroxisome membrane
Peripheral membrane protein
Cytoplasmic side . Shuttles between the cytoplasm and the peroxisomal membrane.
Protein Description Component of the peroxisomal protein import machinery. Together with PEX6, mediates the ATP-dependent relocation and recycling of the peroxisomal targeting signal-1 (PTS1) import receptor PEX5 from the peroxisomal membrane to the cytosol, where it is then available for another round of protein import into the organelle..
Protein Sequence MTTTKRLKFENLRIQFSNAIVGNFLRLPHSIINVLESTNYAIQEFGIAVHSHNSDIPIVHLGWDGHDSGSSENVVLINPVLATVYDLNQKSPLVDLYIQRYDHTHLATEVYVTPETSDDWEIIDANAMRFQNGEILHQTRIVTPGETLICYLEGIVTKFKIDRVEPSMKSARITDGSLVVVAPKVNKTRLVKAEYGHSNKTILKNGAIQLLKKVILRSTVCKMDFPKDNLFVVYISDGAQLPSQKGYASIVKCSLRQSKKSDSDNKSVGIPSKKIGVFIKCDSQIPENHIALSSHLWDAFFTHPMNGAKIKLEFLQMNQANIISGRNATVNIKYFGKDVPTKSGDQYSKLLGGSLLTNNLILPTEQIIIEIKKGESEQQLCNLNEISNESVQWKVTQMGKEEVKDIIERHLPKHYHVKETGEVSRTSKDEDDFITVNSIKKEMVNYLTSPIIATPAIILDGKQGIGKTRLLKELINEVEKDHHIFVKYADCETLHETSNLDKTQKLIMEWCSFCYWYGPSLIVLDNVEALFGKPQANDGDPSNNGQWDNASKLLNFFINQVTKIFNKDNKRIRVLFSGKQKTQINPLLFDKHFVSETWSLRAPDKHARAKLLEYFFSKNQIMKLNRDLQFSDLSLETEGFSPLDLEIFTEKIFYDLQLERDCDNVVTRELFSKSLSAFTPSALRGVKLTKETNIKWGDIGALANAKDVLLETLEWPTKYEPIFVNCPLRLRSGILLYGYPGCGKTLLASAVAQQCGLNFISVKGPEILNKFIGASEQNIRELFERAQSVKPCILFFDEFDSIAPKRGHDSTGVTDRVVNQLLTQMDGAEGLDGVYILAATSRPDLIDSALLRPGRLDKSVICNIPTESERLDILQAIVNSKDKDTGQKKFALEKNADLKLIAEKTAGFSGADLQGLCYNAYLKSVHRWLSAADQSEVVPGNDNIEYFSINEHGRREENRLRLKTLLQQDVVHETKTSTSAASELTAVVTINDLLEACQETKPSISTSELVKLRGIYDRFQKDRNGEMPNGENSIDIGSRLSLM
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
263PhosphorylationRQSKKSDSDNKSVGI
HCCCCCCCCCCCCCC		50.6119779198
552UbiquitinationGQWDNASKLLNFFIN
CCCCCHHHHHHHHHH		55.3617644757
563UbiquitinationFFINQVTKIFNKDNK
HHHHHHHHHHCCCCC		46.5817644757
610AcetylationPDKHARAKLLEYFFS
CCHHHHHHHHHHHCC		48.3124489116
744UbiquitinationYGYPGCGKTLLASAV
ECCCCCCHHHHHHHH		39.8217644757
763UbiquitinationGLNFISVKGPEILNK
CCCEEEECCHHHHHH		63.0617644757
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of PEX1_YEAST !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of PEX1_YEAST !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of PEX1_YEAST !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
PEX6_YEASTPEX6physical
15634331
PEX6_YEASTPEX6physical
16911527
PEX5_YEASTPEX5physical
16911527
PEX15_YEASTPEX15physical
16911527
PEX13_YEASTPEX13physical
16911527
PEX14_YEASTPEX14physical
16911527
PEX17_YEASTPEX17physical
16911527
PEX10_YEASTPEX10physical
16911527
PEX8_YEASTPEX8physical
16911527
PEX6_YEASTPEX6physical
18719252
SLT2_YEASTSLT2genetic
20526336
PEX6_YEASTPEX6physical
22710083
PEX6_YEASTPEX6physical
22500805
UBP15_YEASTUBP15physical
21665945
PEX12_YEASTPEX12genetic
23891562
ATG36_YEASTATG36genetic
24657987
PEX6_YEASTPEX6physical
16007078
PEX15_YEASTPEX15physical
16007078
PEX5_YEASTPEX5physical
16007078
PEX6_YEASTPEX6physical
25659908
PEX15_YEASTPEX15physical
25659908
PEX6_YEASTPEX6physical
26066397
PEX6_YEASTPEX6physical
26170309
PEX13_YEASTPEX13genetic
27708008
LCB2_YEASTLCB2genetic
27708008
MPPA_YEASTMAS2genetic
27708008
DPOD2_YEASTPOL31genetic
27708008
CH10_YEASTHSP10genetic
27708008
MED10_YEASTNUT2genetic
27708008
ODPB_YEASTPDB1genetic
27708008
THRC_YEASTTHR4genetic
27708008
GPR1_YEASTGPR1genetic
27708008
RXT3_YEASTRXT3genetic
27708008
PLP1_YEASTPLP1genetic
27708008
SGPL_YEASTDPL1genetic
27708008
CAJ1_YEASTCAJ1genetic
27708008
ODPA_YEASTPDA1genetic
27708008
DLDH_YEASTLPD1genetic
27708008
YG036_YEASTYGL036Wgenetic
27708008
NPR3_YEASTNPR3genetic
27708008
HTD2_YEASTHTD2genetic
27708008
LPLA_YEASTAIM22genetic
27708008
YJ24_YEASTKCH1genetic
27708008
MRT4_YEASTMRT4genetic
27708008
MSN4_YEASTMSN4genetic
27708008
YL053_YEASTYLR053Cgenetic
27708008
ENV10_YEASTENV10genetic
27708008
LIPB_YEASTLIP2genetic
27708008
SIW14_YEASTSIW14genetic
27708008
ATG3_YEASTATG3genetic
27708008
NOP12_YEASTNOP12genetic
27708008
INO4_YEASTINO4genetic
27708008
VPS17_YEASTVPS17genetic
27708008
LIPA_YEASTLIP5genetic
27708008
FABD_YEASTMCT1genetic
27708008
PMA2_YEASTPMA2genetic
27708008
RL21B_YEASTRPL21Bgenetic
27708008
YAR1_YEASTYAR1genetic
27708008
ATG41_YEASTICY2genetic
27708008
PEX6_YEASTPEX6physical
26842748
PEX5_YEASTPEX5physical
26842748
PEX18_YEASTPEX18physical
26842748
PEX15_YEASTPEX15physical
26842748
PEX12_YEASTPEX12physical
26842748
PEX14_YEASTPEX14physical
26842748
PEX17_YEASTPEX17physical
26842748
PEX13_YEASTPEX13physical
26842748
PEX6_YEASTPEX6physical
29321502
PEX15_YEASTPEX15physical
29321502
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of PEX1_YEAST

loading...

Related Literatures of Post-Translational Modification

TOP
© 2024 Institute of Bioinformatics and Systems Biology, NYCU | Designed by : BiOmics Laboratory