UBP15_YEAST - dbPTM
UBP15_YEAST - PTM Information in dbPTM
Basic Information of Protein
UniProt ID UBP15_YEAST
UniProt AC P50101
Protein Name Ubiquitin carboxyl-terminal hydrolase 15
Gene Name UBP15
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length 1230
Subcellular Localization
Protein Description
Protein Sequence MSSEDELGSIGTVFPGSPIDKSIGSILPQFDEEVETLLEDSFTWNIPDWNELTNPKYNSPRFRIGDFEWDILLFPQGNHNKGVAVYLEPHPEEKLDETTGEMVPVDPDWYCCAQFAIGISRPGNGDTINLINKSHHRFNALDTDWGFANLIDLNNLKHPSKGRPLSFLNEGTLNITAYVRILKDPTGVLWHNFLNYDSKKVTGYVGFRNQGATCYLNSLLQSYFFTKYFRKLVYEIPTEHESPNNSVPLALQRAFYQLQVSDIPLDTLELTRSFGWDTAESFTQHDVQELNRILMDRLENNMKGTPVEGKLNEIFVGKMKSYIKCINVDYESARVEDFWDLQLNVKNFKNLQESFDNYIEMELMNGENQYAAQDYGLQDAQKGVIFESFPPVLHLQLKRFEYDFNYDQMVKVNDKYEFPETIDLSPFVDKDVLKKTLDSENKDKNPYVYNLHGVLVHSGDISTGHYYTLIKPGVEDQWYRFDDERVWRVTKKQVFQENFGCDRLPDEKVRTMTRGEYQNYIIQRHTSAYMLVYIRQEQEEDLLRPVLESDVPKHVITRVREEIKERETKEKEIREAHLYVTLRLHSIKEFIHYEGFDYFAHDGFRLFAEELNDSGLQQINLKVLRTTKLSDIFASIKETMNIPQERDVKYWKMDYRRNSTLRLTQPINFESVNITLQEALKKEKKRTMQTQYGEEGVASTEEDDKALLETVSFLDLFIEEPYLELQFLNKLKEASLISKAQLDDELISTIRTNLPELTKGGIEPVFATDNKSNLLFVKSYDPHTQKLLGFGHFAVNQLQQLSDISAIIEDSISSNEKLTFYEEVQPGTINEIYMKETIYDADIDTGDIVSFEVPGAVLPDTFPVYATIKDFYSYLRYRVKLKFSKFDGSSEEYGVSNEIPESFEFWISAYAPYDDLARMVSKYAHVKPEYLKIIALYSNGRFVLKSTSLLNDYLLKDFNCDQIPPFAFEVLSVPLKELERLRPIKLYWLKNSYIHYQCFEFEVANDYTESQFLEKVQHKIGFTDEEKENILLWTNTNFQFQGLLSDQNTFKDVSKHSLLFGRILPEESKLFKELNRLENVQTSSLEDFMDDENATDRPMDDEQDLGMAIEHSEDMKGRIVVVQQYFKDLENRHGISFLFNLIPDETFPKTKDRLHAKFGLGQKEFSKIKLSIGYSTEEGTVFRSLQGFSDEELDKVILYDIMSNLDYIYMDHPDRLRSHSSYDRPMIIKN
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
2Phosphorylation------MSSEDELGS
------CCCHHHCCC		54.4628152593
9PhosphorylationSSEDELGSIGTVFPG
CCHHHCCCCCCCCCC		30.3930377154
12PhosphorylationDELGSIGTVFPGSPI
HHCCCCCCCCCCCCC		19.8030377154
17PhosphorylationIGTVFPGSPIDKSIG
CCCCCCCCCCCCHHH		20.9428152593
81UbiquitinationFPQGNHNKGVAVYLE
ECCCCCCCCEEEEEC		47.4117644757
157UbiquitinationLIDLNNLKHPSKGRP
CCCCCCCCCCCCCCC		56.4417644757
227UbiquitinationLQSYFFTKYFRKLVY
HHHHHHHHHHHHHHH		36.9217644757
242PhosphorylationEIPTEHESPNNSVPL
CCCCCCCCCCCCCCH		34.5319779198
303UbiquitinationDRLENNMKGTPVEGK
HHHHHCCCCCCCCCC		62.8523749301
508UbiquitinationCDRLPDEKVRTMTRG
CCCCCCHHHEECCHH		44.3823749301
511PhosphorylationLPDEKVRTMTRGEYQ
CCCHHHEECCHHHHH		26.3627017623
635PhosphorylationKLSDIFASIKETMNI
CHHHHHHHHHHHCCC		24.3624930733
687PhosphorylationLKKEKKRTMQTQYGE
HHHHHHHHHHHHCCC		23.6329688323
690PhosphorylationEKKRTMQTQYGEEGV
HHHHHHHHHCCCCCC		16.9729688323
692PhosphorylationKRTMQTQYGEEGVAS
HHHHHHHCCCCCCCC		29.8627017623
699PhosphorylationYGEEGVASTEEDDKA
CCCCCCCCCHHHHHH		33.6729688323
700PhosphorylationGEEGVASTEEDDKAL
CCCCCCCCHHHHHHH		33.3929688323
771UbiquitinationPVFATDNKSNLLFVK
EEEECCCCCCEEEEE		43.4623749301
1019AcetylationFLEKVQHKIGFTDEE
HHHHHHHHHCCCHHH		27.6822865919
1055AcetylationNTFKDVSKHSLLFGR
CCHHCHHHHHHHHCC		36.7424489116
1083PhosphorylationRLENVQTSSLEDFMD
HHHCCCCCCHHHHCC		18.8127017623
1084PhosphorylationLENVQTSSLEDFMDD
HHCCCCCCHHHHCCC		38.8819779198
1095PhosphorylationFMDDENATDRPMDDE
HCCCCCCCCCCCCCH		44.0927017623
1127AcetylationVVVQQYFKDLENRHG
EEEEEHHHHHHHCCC		57.3724489116
1127UbiquitinationVVVQQYFKDLENRHG
EEEEEHHHHHHHCCC		57.3723749301
1149UbiquitinationIPDETFPKTKDRLHA
CCCCCCCCCHHHHHH		65.1117644757
1163UbiquitinationAKFGLGQKEFSKIKL
HHCCCCCHHHCEEEE		59.9523749301
1163AcetylationAKFGLGQKEFSKIKL
HHCCCCCHHHCEEEE		59.9524489116
1218PhosphorylationDHPDRLRSHSSYDRP
CCCHHHHCCCCCCCC		32.1127017623
1220PhosphorylationPDRLRSHSSYDRPMI
CHHHHCCCCCCCCCC		31.6630377154
1221PhosphorylationDRLRSHSSYDRPMII
HHHHCCCCCCCCCCC		26.1527017623
1229UbiquitinationYDRPMIIKN------
CCCCCCCCC------		45.7617644757
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of UBP15_YEAST !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of UBP15_YEAST !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of UBP15_YEAST !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
ACE2_YEASTACE2physical
11805826
BCK1_YEASTBCK1physical
11805826
CDC11_YEASTCDC11physical
11805826
ECM30_YEASTECM30physical
11805826
MNL1_YEASTMNL1physical
11805826
IML1_YEASTIML1physical
11805826
MTR4_YEASTMTR4physical
11805826
MYO2_YEASTMYO2physical
11805826
SEC3_YEASTSEC3physical
11805826
YBE4_YEASTYBL044Wphysical
11805826
ALAT_YEASTALT2physical
11805826
NOL10_YEASTENP2physical
11805826
YJ68_YEASTYJR098Cphysical
11805826
DRE2_YEASTDRE2physical
11805826
EMW1_YEASTEMW1physical
11805826
RGC1_YEASTRGC1physical
11805826
UBP14_YEASTUBP14physical
16554755
IDHP_YEASTIDP1physical
16554755
DHE2_YEASTGDH2physical
16554755
SAC3_YEASTSAC3physical
16554755
SSD1_YEASTSSD1physical
16554755
PAD1_YEASTPAD1physical
16554755
SNU13_YEASTSNU13physical
16554755
MLC1_YEASTMLC1physical
16554755
2ABA_YEASTCDC55physical
16554755
ASK10_YEASTASK10physical
16554755
NOP56_YEASTNOP56physical
16554755
ECM30_YEASTECM30physical
16554755
DED1_YEASTDED1physical
16429126
UBP4_YEASTDOA4physical
16429126
ECM30_YEASTECM30physical
16429126
TBB_YEASTTUB2physical
16429126
PYR1_YEASTURA2physical
16429126
DBF4_YEASTDBF4genetic
17314980
DDR48_YEASTDDR48genetic
17314980
SRB8_YEASTSRB8genetic
17314980
NUP84_YEASTNUP84genetic
17314980
SWD3_YEASTSWD3genetic
17314980
RAD3_YEASTRAD3genetic
17314980
SLX5_YEASTSLX5genetic
17314980
UBP3_YEASTUBP3genetic
17314980
DOA1_YEASTDOA1genetic
17314980
UBC4_YEASTUBC4genetic
17314980
MED11_YEASTMED11genetic
17314980
UBP6_YEASTUBP6genetic
17314980
HSP42_YEASTHSP42physical
19536198
ECM30_YEASTECM30physical
20093466
YM35_YEASTYMR160Wphysical
20093466
ECM30_YEASTECM30physical
20620961
CDH1_YEASTCDH1physical
21710968
UBP15_YEASTUBP15physical
22940862
PYR1_YEASTURA2physical
22940862
PEX6_YEASTPEX6physical
21665945
UBI4P_YEASTUBI4physical
21665945
PEX5_YEASTPEX5physical
21665945
SECU_YEASTPDS1physical
22072716
RL40_HUMANUBA52physical
10527495
CGS5_YEASTCLB5genetic
25877870
CDH1_YEASTCDH1physical
25877870
CGS5_YEASTCLB5physical
25877870
RSP5_YEASTRSP5genetic
27708008
CHO2_YEASTCHO2genetic
27708008
ILM1_YEASTILM1genetic
27708008
DHOM_YEASTHOM6genetic
27708008
GTR1_YEASTGTR1genetic
27708008
UBP4_YEASTDOA4genetic
28298493
UBP3_YEASTUBP3genetic
28298493
ECM30_YEASTECM30physical
28298493
STE12_YEASTSTE12physical
28298493
DIG1_YEASTDIG1physical
28298493
DIG2_YEASTDIG2physical
28298493
TEC1_YEASTTEC1physical
28298493
ECM21_YEASTECM21physical
28298493
FPK1_YEASTFPK1physical
28298493
MLF3_YEASTMLF3physical
28298493
YAK1_YEASTYAK1physical
28298493
HPH1_YEASTFRT1physical
28298493
LST4_YEASTLST4physical
28298493
CLA4_YEASTCLA4physical
28298493
SBE22_YEASTSBE22physical
28298493
PMD1_YEASTPMD1physical
28298493
ROD1_YEASTROD1physical
28298493
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of UBP15_YEAST

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Related Literatures of Post-Translational Modification

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