UTP12_YEAST - dbPTM
UTP12_YEAST - PTM Information in dbPTM
Basic Information of Protein
UniProt ID UTP12_YEAST
UniProt AC Q12220
Protein Name U3 small nucleolar RNA-associated protein 12
Gene Name DIP2
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length 943
Subcellular Localization Nucleus, nucleolus .
Protein Description Involved in nucleolar processing of pre-18S ribosomal RNA..
Protein Sequence MVKSYQRFEQAAAFGVIASNANCVWIPASSGNSNGSGPGQLITSALEDVNIWDIKTGDLVSKLSDGLPPGASDARGAKPAECTYLEAHKDTDLLAVGYADGVIKVWDLMSKTVLLNFNGHKAAITLLQFDGTGTRLISGSKDSNIIVWDLVGEVGLYKLRSHKDSITGFWCQGEDWLISTSKDGMIKLWDLKTHQCIETHIAHTGECWGLAVKDDLLITTGTDSQVKIWKLDIENDKMGGKLTEMGIFEKQSKQRGLKIEFITNSSDKTSFFYIQNADKTIETFRIRKEEEIARGLKKREKRLKEKGLTEEEIAKSIKESYSSFILHPFQTIRSLYKIKSASWTTVSSSKLELVLTTSSNTIEYYSIPYEKRDPTSPAPLKTHTIELQGQRTDVRSIDISDDNKLLATASNGSLKIWNIKTHKCIRTFECGYALTCKFLPGGLLVILGTRNGELQLFDLASSSLLDTIEDAHDAAIWSLDLTSDGKRLVTGSADKTVKFWDFKVENSLVPGTKNKFLPVLKLHHDTTLELTDDILCVRVSPDDRYLAISLLDNTVKVFFLDSMKFYLSLYGHKLPVLSIDISFDSKMIITSSADKNIKIWGLDFGDCHKSLFAHQDSIMNVKFLPQSHNFFSCSKDAVVKYWDGEKFECIQKLYAHQSEVWALAVATDGGFVVSSSHDHSIRIWEETEDQVFLEEEKEKELEEQYEDTLLTSLEEGNGDDAFKADASGEGVEDEASGVHKQTLESLKAGERLMEALDLGIAEIEGLEAYNRDMKLWQRKKLGEAPIKPQGNAVLIAVNKTPEQYIMDTLLRIRMSQLEDALMVMPFSYVLKFLKFIDTVMQNKTLLHSHLPLICKNLFFIIKFNHKELVSQKNEELKLQINRVKTELRSALKSTEDDLGFNVQGLKFVKQQWNLRHNYEFVDEYDQQEKESNSARKRVFGTVI
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
237AcetylationKLDIENDKMGGKLTE
EEECCCCCCCCEEEE		51.5324489116
350MethylationWTTVSSSKLELVLTT
EEEECCCEEEEEEEC		48.1820137074
375PhosphorylationPYEKRDPTSPAPLKT
CCCCCCCCCCCCCEE		52.1919684113
376PhosphorylationYEKRDPTSPAPLKTH
CCCCCCCCCCCCEEE		25.1819684113
515AcetylationLVPGTKNKFLPVLKL
CCCCCCCCCEEEEEE		50.2424489116
562PhosphorylationVKVFFLDSMKFYLSL
EEEEEECHHHHHHHH		26.4729688323
566PhosphorylationFLDSMKFYLSLYGHK
EECHHHHHHHHHCCC		7.0029688323
568PhosphorylationDSMKFYLSLYGHKLP
CHHHHHHHHHCCCCC		14.2529688323
570PhosphorylationMKFYLSLYGHKLPVL
HHHHHHHHCCCCCEE		17.5129688323
635AcetylationHNFFSCSKDAVVKYW
CCCCCCCCCEEEEEC		54.7724489116
727PhosphorylationDAFKADASGEGVEDE
CCCCCCCCCCCCCCC		37.6122369663
736PhosphorylationEGVEDEASGVHKQTL
CCCCCCCCCCCHHHH		39.0221551504
909AcetylationVQGLKFVKQQWNLRH
CCHHHHHHHHHHCCC		39.6524489116
929AcetylationDEYDQQEKESNSARK
CCHHHHHHHCHHHHH		63.2024489116
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of UTP12_YEAST !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of UTP12_YEAST !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of UTP12_YEAST !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
MPP10_YEASTMPP10physical
12068309
UBP10_YEASTUBP10physical
18467557
UTP21_YEASTUTP21physical
18725399
UTP13_YEASTUTP13physical
18725399
RPB1_YEASTRPO21genetic
27708008
PRS8_YEASTRPT6genetic
27708008
RPF1_YEASTRPF1genetic
27708008
NOP2_YEASTNOP2genetic
27708008
RPC6_YEASTRPC34genetic
27708008
STU1_YEASTSTU1genetic
27708008
CDC27_YEASTCDC27genetic
27708008
SLI15_YEASTSLI15genetic
27708008
KRR1_YEASTKRR1genetic
27708008
FBRL_YEASTNOP1genetic
27708008
FAD1_YEASTFAD1genetic
27708008
NHP2_YEASTNHP2genetic
27708008
YRB1_YEASTYRB1genetic
27708008
DAD1_YEASTDAD1genetic
27708008
FAL1_YEASTFAL1genetic
27708008
CDC37_YEASTCDC37genetic
27708008
CDC1_YEASTCDC1genetic
27708008
FCF1_YEASTFCF1genetic
27708008
UTP5_YEASTUTP5genetic
27708008
UTP6_YEASTUTP6genetic
27708008
RMRP_YEASTSNM1genetic
27708008
SMT3_YEASTSMT3genetic
27708008
SP105_YEASTSPC105genetic
27708008
DAM1_YEASTDAM1genetic
27708008
RRP3_YEASTRRP3genetic
27708008
RRP4_YEASTRRP4genetic
27708008
UTP9_YEASTUTP9genetic
27708008
ATC7_YEASTNEO1genetic
27708008
NUP85_YEASTNUP85genetic
27708008
KTHY_YEASTCDC8genetic
27708008
IMB1_YEASTKAP95genetic
27708008
UTP15_YEASTUTP15genetic
27708008
RRP5_YEASTRRP5genetic
27708008
HAS1_YEASTHAS1genetic
27708008
NAT10_YEASTKRE33genetic
27708008
NSL1_YEASTNSL1genetic
27708008
DIM1_YEASTDIM1genetic
27708008
SEC23_YEASTSEC23genetic
27708008
ATG15_YEASTATG15genetic
27708008
NOP6_YEASTNOP6genetic
27708008
RRP8_YEASTRRP8genetic
27708008
ACL4_YEASTYDR161Wgenetic
27708008
CP56_YEASTDIT2genetic
27708008
MSH4_YEASTMSH4genetic
27708008
DAL81_YEASTDAL81genetic
27708008
RL1D1_YEASTUTP30genetic
27708008
HBS1_YEASTHBS1genetic
27708008
RM39_YEASTMRPL39genetic
27708008
SCS7_YEASTSCS7genetic
27708008
DOM34_YEASTDOM34genetic
27708008
MAS5_YEASTYDJ1genetic
27708008
BUD21_YEASTBUD21genetic
27708008
WHI5_YEASTWHI5genetic
27708008
SUR1_YEASTSUR1genetic
27708008
HSP7F_YEASTSSE1genetic
27708008
NIP80_YEASTNIP100genetic
27708008
HDA3_YEASTHDA3genetic
27708008
UTP13_YEASTUTP13physical
27330138
UTP21_YEASTUTP21physical
27330138
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of UTP12_YEAST

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Related Literatures of Post-Translational Modification

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