RRN3_YEAST - dbPTM
RRN3_YEAST - PTM Information in dbPTM
Basic Information of Protein
UniProt ID RRN3_YEAST
UniProt AC P36070
Protein Name RNA polymerase I-specific transcription initiation factor RRN3
Gene Name RRN3
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length 627
Subcellular Localization Nucleus .
Protein Description Required for efficient transcription initiation by RNA polymerase I. Interacts with Pol I in the absence of template DNA and stimulates recruitment of Pol I, but does not remain as part of stable preinitiation complex..
Protein Sequence MMAFENTSKRPPQDFVAPIDQKKRKVQFSDSTGLVTLQPEEIKDEVFSAAMYSRFVKSALDDLDKNDSTQIGIIANQVALPSKNPERINDKNLNILLDILSSNINRIESSRGTFLIQSIINFEKWWELPPHTLSKYIYFIKILCSSIPKWWQDVSMILVSCFILPIKQTVCHHDMLKYFLRMIPSSMGFIDTYLAKFFPNKNDTRRKLVNYTSNLLKLRGYCSELGFQIWSLLIEKIISIDVELQNELDELDDDVDDDDLEEVDLEDDDDLDDDSGDDDDENCGNSNEELRSGAADGSQSDSEDMDIIEGMDGTEEYNVELTQGIKELSTKLDSILTLVSTHVEEQVTPESLESGEGVGVFNTLTTLFKTHVLPTYYTRSIQYIMFHVSQQQLELMDSFLVTLIDISFAVNEAAEKKIKSLQYLGSYIARAKKLSRTQIIFVASYLTSWLNRYVIEREEEVDQRGGMERFKHFYAAFQALCYIFCFRHNIFRDTDGNWECELDKFFQRMVISKFNPLKFCNENVMLMFARIAQQESVAYCFSIIENNNNERLRGIIGKADSDKKENSAQANTTSSSWSLATRQQFIDLQSYFPYDPLFLKNYKILMKEYYIEWSEASGEYESDGSDD
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
186PhosphorylationFLRMIPSSMGFIDTY
HHHHCHHHHCHHHHH		19.9930377154
193PhosphorylationSMGFIDTYLAKFFPN
HHCHHHHHHHHHCCC		10.8330377154
567PhosphorylationDSDKKENSAQANTTS
CCCCCCCCCCCCCCC		23.8927017623
572PhosphorylationENSAQANTTSSSWSL
CCCCCCCCCCCHHHH		30.9427017623
573PhosphorylationNSAQANTTSSSWSLA
CCCCCCCCCCHHHHH		26.8127017623
574PhosphorylationSAQANTTSSSWSLAT
CCCCCCCCCHHHHHH		21.9727017623
575PhosphorylationAQANTTSSSWSLATR
CCCCCCCCHHHHHHH		33.4627017623
576PhosphorylationQANTTSSSWSLATRQ
CCCCCCCHHHHHHHH		22.0527017623
578PhosphorylationNTTSSSWSLATRQQF
CCCCCHHHHHHHHHH		15.2927017623
581PhosphorylationSSSWSLATRQQFIDL
CCHHHHHHHHHHCCH		34.0127017623
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of RRN3_YEAST !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of RRN3_YEAST !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of RRN3_YEAST !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
RRN6_YEASTRRN6physical
11032814
TAF12_YEASTTAF12physical
12015311
RPA43_YEASTRPA43genetic
11032814
RPA49_YEASTRPA49genetic
18086878
NOP53_YEASTNOP53physical
18631361
FBRL_YEASTNOP1physical
20421203
DPOA_YEASTPOL1physical
20421203
RRN3_YEASTRRN3physical
21940764
GPN2_YEASTGPN2genetic
23267056
RPA43_YEASTRPA43physical
23640330
GPR1_YEASTGPR1genetic
27708008
MRM2_YEASTMRM2genetic
27708008
KPC1_YEASTPKC1genetic
27708008
APC11_YEASTAPC11genetic
27708008
FAD1_YEASTFAD1genetic
27708008
DBF4_YEASTDBF4genetic
27708008
SNU56_YEASTSNU56genetic
27708008
GPI8_YEASTGPI8genetic
27708008
UTP5_YEASTUTP5genetic
27708008
MOB2_YEASTMOB2genetic
27708008
ACT_YEASTACT1genetic
27708008
ALG2_YEASTALG2genetic
27708008
CDC20_YEASTCDC20genetic
27708008
PRP18_YEASTPRP18genetic
27708008
PRP38_YEASTPRP38genetic
27708008
FDFT_YEASTERG9genetic
27708008
UTP9_YEASTUTP9genetic
27708008
RRN7_YEASTRRN7genetic
27708008
CDC11_YEASTCDC11genetic
27708008
UTP15_YEASTUTP15genetic
27708008
NOP2_YEASTNOP2genetic
27708008
CH10_YEASTHSP10genetic
27708008
MED4_YEASTMED4genetic
27708008
SEC63_YEASTSEC63genetic
27708008
IF6_YEASTTIF6genetic
27708008
ATC3_YEASTDRS2genetic
27708008
BUD31_YEASTBUD31genetic
27708008
RPA14_YEASTRPA14genetic
27708008
YD249_YEASTYDR249Cgenetic
27708008
IES5_YEASTIES5genetic
27708008
IES1_YEASTIES1genetic
27708008
YFF2_YEASTYFL052Wgenetic
27708008
LSB3_YEASTLSB3genetic
27708008
PUF4_YEASTPUF4genetic
27708008
VAM7_YEASTVAM7genetic
27708008
STF2_YEASTSTF2genetic
27708008
GTR2_YEASTGTR2genetic
27708008
TNA1_YEASTTNA1genetic
27708008
OPI1_YEASTOPI1genetic
27708008
SNF6_YEASTSNF6genetic
27708008
STB5_YEASTSTB5genetic
27708008
RPA34_YEASTRPA34genetic
27708008
SIC1_YEASTSIC1genetic
27708008
YL149_YEASTYLR149Cgenetic
27708008
LIPB_YEASTLIP2genetic
27708008
SYM1_YEASTSYM1genetic
27708008
ROM2_YEASTROM2genetic
27708008
ATP18_YEASTATP18genetic
27708008
HDA1_YEASTHDA1genetic
27708008
OCA2_YEASTOCA2genetic
27708008
RL9B_YEASTRPL9Bgenetic
27708008
NST1_YEASTNST1genetic
27708008
OCA1_YEASTOCA1genetic
27708008
YNO0_YEASTYNL140Cgenetic
27708008
YO029_YEASTYOL029Cgenetic
27708008
STI1_YEASTSTI1genetic
27708008
SFL1_YEASTSFL1genetic
27708008
HSP7F_YEASTSSE1genetic
27708008
YP013_YEASTCMR3genetic
27708008
MED1_YEASTMED1genetic
27708008
YP089_YEASTYPR089Wgenetic
27708008
HDA3_YEASTHDA3genetic
27708008
RPA1_YEASTRPA190physical
28262097
RPAC1_YEASTRPC40physical
28262097
RPAC2_YEASTRPC19physical
28262097
RPA43_YEASTRPA43physical
28262097
RPA14_YEASTRPA14physical
28262097
RPA2_YEASTRPA135physical
28262097
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of RRN3_YEAST

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Related Literatures of Post-Translational Modification

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