RL26A_YEAST - dbPTM
RL26A_YEAST - PTM Information in dbPTM
Basic Information of Protein
UniProt ID RL26A_YEAST
UniProt AC P05743
Protein Name 60S ribosomal protein L26-A {ECO:0000303|PubMed:9559554}
Gene Name RPL26A {ECO:0000303|PubMed:9559554}
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length 127
Subcellular Localization Cytoplasm .
Protein Description Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules. The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain. The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel..
Protein Sequence MAKQSLDVSSDRRKARKAYFTAPSSQRRVLLSAPLSKELRAQYGIKALPIRRDDEVLVVRGSKKGQEGKISSVYRLKFAVQVDKVTKEKVNGASVPINLHPSKLVITKLHLDKDRKALIQRKGGKLE
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
32-Hydroxyisobutyrylation-----MAKQSLDVSS
-----CCCCCCCCCC		38.84-
3Succinylation-----MAKQSLDVSS
-----CCCCCCCCCC		38.8423954790
5Phosphorylation---MAKQSLDVSSDR
---CCCCCCCCCCHH		26.3225704821
9PhosphorylationAKQSLDVSSDRRKAR
CCCCCCCCCHHHHHH		26.6230377154
10PhosphorylationKQSLDVSSDRRKARK
CCCCCCCCHHHHHHH		34.6827214570
14UbiquitinationDVSSDRRKARKAYFT
CCCCHHHHHHHHHCC		54.1322817900
17UbiquitinationSDRRKARKAYFTAPS
CHHHHHHHHHCCCCH		52.9122817900
17AcetylationSDRRKARKAYFTAPS
CHHHHHHHHHCCCCH		52.9124489116
19PhosphorylationRRKARKAYFTAPSSQ
HHHHHHHHCCCCHHH		12.4222369663
21PhosphorylationKARKAYFTAPSSQRR
HHHHHHCCCCHHHCE		25.6122369663
24PhosphorylationKAYFTAPSSQRRVLL
HHHCCCCHHHCEEEE		36.3220377248
25PhosphorylationAYFTAPSSQRRVLLS
HHCCCCHHHCEEEEC		27.0120377248
32PhosphorylationSQRRVLLSAPLSKEL
HHCEEEECCCCCHHH		24.5522369663
36PhosphorylationVLLSAPLSKELRAQY
EEECCCCCHHHHHHH		24.0322369663
37UbiquitinationLLSAPLSKELRAQYG
EECCCCCHHHHHHHC		69.3323749301
37SuccinylationLLSAPLSKELRAQYG
EECCCCCHHHHHHHC		69.3323954790
37AcetylationLLSAPLSKELRAQYG
EECCCCCHHHHHHHC		69.3324489116
462-HydroxyisobutyrylationLRAQYGIKALPIRRD
HHHHHCCCEEECCCC		39.24-
46UbiquitinationLRAQYGIKALPIRRD
HHHHHCCCEEECCCC		39.2424961812
46SuccinylationLRAQYGIKALPIRRD
HHHHHCCCEEECCCC		39.2423954790
46AcetylationLRAQYGIKALPIRRD
HHHHHCCCEEECCCC		39.2424489116
62PhosphorylationEVLVVRGSKKGQEGK
EEEEEECCCCCCCCC		22.1922369663
63UbiquitinationVLVVRGSKKGQEGKI
EEEEECCCCCCCCCC		64.8422817900
64UbiquitinationLVVRGSKKGQEGKIS
EEEECCCCCCCCCCC		68.4722817900
69UbiquitinationSKKGQEGKISSVYRL
CCCCCCCCCCEEEEE		38.3723749301
71PhosphorylationKGQEGKISSVYRLKF
CCCCCCCCEEEEEEE		19.7621440633
72PhosphorylationGQEGKISSVYRLKFA
CCCCCCCEEEEEEEE		27.0020377248
772-HydroxyisobutyrylationISSVYRLKFAVQVDK
CCEEEEEEEEEEEEE		23.44-
77AcetylationISSVYRLKFAVQVDK
CCEEEEEEEEEEEEE		23.4424489116
84AcetylationKFAVQVDKVTKEKVN
EEEEEEEECCHHHCC		53.6124489116
84UbiquitinationKFAVQVDKVTKEKVN
EEEEEEEECCHHHCC		53.6123749301
86PhosphorylationAVQVDKVTKEKVNGA
EEEEEECCHHHCCCE		38.9521440633
87UbiquitinationVQVDKVTKEKVNGAS
EEEEECCHHHCCCEE		59.5322817900
87AcetylationVQVDKVTKEKVNGAS
EEEEECCHHHCCCEE		59.5324489116
89UbiquitinationVDKVTKEKVNGASVP
EEECCHHHCCCEECC		42.4223749301
89AcetylationVDKVTKEKVNGASVP
EEECCHHHCCCEECC		42.4224489116
94PhosphorylationKEKVNGASVPINLHP
HHHCCCEECCCEECH		29.8022369663
102PhosphorylationVPINLHPSKLVITKL
CCCEECHHHEEEEEE		28.0721440633
103SuccinylationPINLHPSKLVITKLH
CCEECHHHEEEEEEE		51.7523954790
103AcetylationPINLHPSKLVITKLH
CCEECHHHEEEEEEE		51.7524489116
108AcetylationPSKLVITKLHLDKDR
HHHEEEEEEEECHHH		23.8424489116
1082-HydroxyisobutyrylationPSKLVITKLHLDKDR
HHHEEEEEEEECHHH		23.84-
113SuccinylationITKLHLDKDRKALIQ
EEEEEECHHHHHHHH		66.8323954790
113AcetylationITKLHLDKDRKALIQ
EEEEEECHHHHHHHH		66.8324489116
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of RL26A_YEAST !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of RL26A_YEAST !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of RL26A_YEAST !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
RL26B_YEASTRPL26Bgenetic
22377630
RL26B_YEASTRPL26Bgenetic
22688513
YCY0_YEASTYCR090Cgenetic
27708008
RMD5_YEASTRMD5genetic
27708008
MED20_YEASTSRB2genetic
27708008
RS21A_YEASTRPS21Agenetic
27708008
HDA1_YEASTHDA1genetic
27708008
RDL1_YEASTRDL1genetic
27708008
RL21B_YEASTRPL21Bgenetic
27708008
PNG1_YEASTPNG1genetic
27708008
NCBP2_YEASTCBC2genetic
27708008
YAR1_YEASTYAR1genetic
27708008
CDC37_YEASTCDC37genetic
27708008
CDC4_YEASTCDC4genetic
27708008
MED6_YEASTMED6genetic
27708008
SPC97_YEASTSPC97genetic
27708008
NTR2_YEASTNTR2genetic
27708008
NUF2_YEASTNUF2genetic
27708008
IPL1_YEASTIPL1genetic
27708008
RL19A_YEASTRPL19Bgenetic
27708008
RL19B_YEASTRPL19Bgenetic
27708008
SNF5_YEASTSNF5genetic
27708008
ABP1_YEASTABP1genetic
27708008
YCZ2_YEASTYCR102Cgenetic
27708008
RM01_YEASTMRPL1genetic
27708008
LSM6_YEASTLSM6genetic
27708008
MGDP1_YEASTYER134Cgenetic
27708008
YGS6_YEASTYGL176Cgenetic
27708008
STF2_YEASTSTF2genetic
27708008
MOG1_YEASTMOG1genetic
27708008
VPS51_YEASTVPS51genetic
27708008
YL149_YEASTYLR149Cgenetic
27708008
SCS7_YEASTSCS7genetic
27708008
LSM7_YEASTLSM7genetic
27708008
MSB4_YEASTMSB4genetic
27708008
KTR1_YEASTKTR1genetic
27708008
PALA_YEASTRIM20genetic
27708008
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of RL26A_YEAST

loading...

Related Literatures of Post-Translational Modification

TOP
© 2024 Institute of Bioinformatics and Systems Biology, NYCU | Designed by : BiOmics Laboratory