KTR1_YEAST - dbPTM
KTR1_YEAST - PTM Information in dbPTM
Basic Information of Protein
UniProt ID KTR1_YEAST
UniProt AC P27810
Protein Name Alpha-1,2 mannosyltransferase KTR1
Gene Name KTR1
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length 393
Subcellular Localization Golgi apparatus membrane
Single-pass type II membrane protein.
Protein Description Mannosyltransferase that transfers a mannose residue from GDP-mannose to a range of acceptors in vitro, forming an alpha-(1->2)-D-mannosyl-D-mannose linkage..
Protein Sequence MAKIMIPASKQPVYKKLGLLLVAVFTVYVFFHGAQYARGSAPSPKYSTVLSSGSGYKYSKVELPKYTGPREKATFVTLVRNRDLYSLAESIKSVEDRFNSKFNYDWVFLNDEEFTDEFKNVTSALVSGTTKYGVIPKEHWSFPEWIDEEKAAQVRKEMGEKRIIYGDSISYRHMCRFESGFFYRHPLMDDYDWYWRVEPDIKLHCDIDYDVFKFMKDNKKKYAFAISIKEYEATIPTLWETTRKFMEAHPELIHENNMLDFVSDDQGLSYNLCHFWSNFEIAALDLWRSPAYSAYFDYLDREGGFFYERWGDAPVHSIGAALFLDRSEIHHFGDIGYYHVPFHSCPIDTSIRLANKCDCDPSKDFTWHSYSCTTKFYNINKLPKPAGWQNHIG
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
3Ubiquitination-----MAKIMIPASK
-----CCCCEECCCC		31.3524961812
10UbiquitinationKIMIPASKQPVYKKL
CCEECCCCCHHHHHH		61.8123749301
15UbiquitinationASKQPVYKKLGLLLV
CCCCHHHHHHHHHHH		41.5822817900
45AcetylationRGSAPSPKYSTVLSS
CCCCCCCCCEEEECC		57.0524489116
45UbiquitinationRGSAPSPKYSTVLSS
CCCCCCCCCEEEECC		57.0523749301
57AcetylationLSSGSGYKYSKVELP
ECCCCCCCEEEEECC		46.7224489116
57UbiquitinationLSSGSGYKYSKVELP
ECCCCCCCEEEEECC		46.7217644757
60UbiquitinationGSGYKYSKVELPKYT
CCCCCEEEEECCCCC		36.3217644757
65UbiquitinationYSKVELPKYTGPREK
EEEEECCCCCCCCHH		68.9817644757
72UbiquitinationKYTGPREKATFVTLV
CCCCCCHHCEEEEEE		54.7417644757
92UbiquitinationYSLAESIKSVEDRFN
HHHHHHHHCHHHHHH		58.7017644757
101UbiquitinationVEDRFNSKFNYDWVF
HHHHHHCCCCCCEEE		38.4417644757
120N-linked_GlycosylationEFTDEFKNVTSALVS
HHCHHHCHHHHHHHC		47.85-
131UbiquitinationALVSGTTKYGVIPKE
HHHCCCCCCCCCCHH		39.5817644757
137UbiquitinationTKYGVIPKEHWSFPE
CCCCCCCHHHCCCHH		51.6017644757
150UbiquitinationPEWIDEEKAAQVRKE
HHHCCHHHHHHHHHH		47.1517644757
156UbiquitinationEKAAQVRKEMGEKRI
HHHHHHHHHHCCCEE		53.8717644757
161UbiquitinationVRKEMGEKRIIYGDS
HHHHHCCCEEEECCC		43.0717644757
202UbiquitinationWRVEPDIKLHCDIDY
EECCCCEEEEEEECH		39.2917644757
213UbiquitinationDIDYDVFKFMKDNKK
EECHHHHHHHHCCCC		44.3817644757
221UbiquitinationFMKDNKKKYAFAISI
HHHCCCCEEEEEEEH		43.3417644757
229UbiquitinationYAFAISIKEYEATIP
EEEEEEHHEEEECCC		47.6717644757
244UbiquitinationTLWETTRKFMEAHPE
CHHHHHHHHHHHCHH		47.1517644757
356UbiquitinationTSIRLANKCDCDPSK
CHHHHHHCCCCCCCC		26.3317644757
363UbiquitinationKCDCDPSKDFTWHSY
CCCCCCCCCCCEEEE		63.3517644757
375UbiquitinationHSYSCTTKFYNINKL
EEEEEEEEEEECCCC		27.9117644757
381UbiquitinationTKFYNINKLPKPAGW
EEEEECCCCCCCCCC		63.4717644757
381AcetylationTKFYNINKLPKPAGW
EEEEECCCCCCCCCC		63.4722865919
384UbiquitinationYNINKLPKPAGWQNH
EECCCCCCCCCCCCC		58.9217644757
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of KTR1_YEAST !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of KTR1_YEAST !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of KTR1_YEAST !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
THDH_YEASTILV1genetic
21623372
TPS2_YEASTTPS2genetic
21623372
SPEE_YEASTSPE3genetic
21623372
GGPPS_YEASTBTS1genetic
21623372
SVP26_YEASTSVP26physical
24585773
MMS2_YEASTMMS2genetic
27708008
RTG2_YEASTRTG2genetic
27708008
CKS1_YEASTCKS1genetic
27708008
NOP14_YEASTNOP14genetic
27708008
TCPZ_YEASTCCT6genetic
27708008
RSP5_YEASTRSP5genetic
27708008
CDC4_YEASTCDC4genetic
27708008
SWC4_YEASTSWC4genetic
27708008
NOP56_YEASTNOP56genetic
27708008
TAD3_YEASTTAD3genetic
27708008
SEC65_YEASTSEC65genetic
27708008
PSB5_YEASTPRE2genetic
27708008
CUE3_YEASTCUE3genetic
27708008
RTF1_YEASTRTF1genetic
27708008
VMA21_YEASTVMA21genetic
27708008
SNF6_YEASTSNF6genetic
27708008
PTK2_YEASTPTK2genetic
27708008
RAD1_YEASTRAD1genetic
27708008
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of KTR1_YEAST

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Related Literatures of Post-Translational Modification

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